Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

Cisco and Nutanix are both solutions in the HCI category. Additionally, 89% of Cisco users are willing to recommend the solution, compared to 94% of Nutanix users who would recommend it.

Cisco HyperFlex HX-Series [...

Read 90 Cisco HyperFlex HX-Series [EOL] reviews

89% willing to recommend

Nutanix Cloud Infrastructur...

Read 200 Nutanix Cloud Infrastructure (NCI) reviews

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7,305 Comparison Views

94% willing to recommend

Cisco HyperFlex HX-Series [...

Nutanix Cloud Infrastructur...

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Executive SummaryUpdated on Nov 2, 2025

Nutanix Cloud Infrastructure (NCI) and Cisco HyperFlex HX-Series are leaders in hyper-converged infrastructure solutions, competing in enterprise IT environments. NCI seems to have an edge in ease of management and cost-effectiveness, whereas HyperFlex stands out with its strong integration and high availability.

Features: NCI boasts high performance, ease of administration, and seamless integration with its distributed file system. Valued features include data protection, storage auto-tiering, and one-click upgrades. HyperFlex, however, integrates compute, storage, and network, excelling in its ability to integrate with Cisco’s network solutions and offers robust support for various hypervisors, with high availability being a notable strength.

Room for Improvement: NCI could improve network switch convergence, DRC solutions, and enhance built-in backup features, with demands for a more user-friendly interface. HyperFlex's scalability options require enhancement, along with integration tools for external solutions, and users have highlighted the high cost and complexity as deterrents. Better analytics and cloud integration would benefit HyperFlex further.

Ease of Deployment and Customer Service: NCI enables rapid deployment with its intuitive interface and outstanding technical support, consistently appreciated for responsiveness and expertise. HyperFlex's deployment, while effective, can seem complex, with a need for better guidance and documentation. Cisco’s comprehensive support is perceived as slightly less agile than Nutanix, affecting the customer service experience.

Pricing and ROI: NCI is seen as cost-effective, benefiting deployment and operational expenses through inclusive features and reduced infrastructure needs, contributing to faster ROI. Nutanix’s licensing simplicity is favored, albeit with notable upfront costs. HyperFlex, with a higher initial cost, is justified by its integrations and support, although annual subscription costs and licensing complexities suggest areas for improvement.

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HCI

December 2025

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Cisco HyperFlex HX-Series [...

Average Rating

8.0

Reviews Sentiment

6.7

Number of Reviews

Ranking in other categories

No ranking in other categories

Nutanix Cloud Infrastructur...

Average Rating

8.6

Reviews Sentiment

7.3

Number of Reviews

200

Ranking in other categories

Software Defined Storage (SDS) (6th), HCI (5th), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)

Featured Reviews

reviewer2133501

Assistant VP, Information Technology at a financial services firm with 1,001-5,000 employees

Effective deduplication feature, but lacks a unified architecture

Cisco HyperFlex HX-Series could be improved by reducing the number of nodes. Currently, the architecture separates data, computing, memory, and storage into different parts. For example, if I need around 200 servers with a requirement of TB of storage, I would need 200 clusters, which can be quite cumbersome. Other solutions like Dell and Nutanix have a single combined unit that includes computing, memory, and storage, which can reduce the number of nodes required and also reduce licensing and power consumption. Therefore, I suggest improving the architecture of the Cisco HyperFlex HX-Series by combining computing, memory, and storage into a single unit, making it more efficient and easier to manage. It will also reduce the number of nodes required and licensing costs and help to reduce power consumption. I would like to see improved internal integration capabilities in the next release. Currently, it is constrained only to VMware only. So, there is no integration part of the RAC or IEL or anything, and it isn't easy to manage it. If I want to hold another partner, then that part will not be possible. So, you have to manage that particular integration. Another feature could be in terms of memory usage.

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Obasanjo Biliaminu

Head Systems Administration/Security at Nigeria Inter-Bank Settlement System PLC

Infrastructure efficiency has improved significantly with quick server provisioning, though physical to virtual migrations need a streamlined in-house tool

From my experience with Nutanix Cloud Infrastructure (NCI), there is one area that needs improvement. When moving a critical infrastructure from a physical machine to Nutanix Cloud Infrastructure (NCI), we currently have to use a third-party tool to convert the physical machine to a VM. We have to use VMware converter to perform this conversion before moving it to Nutanix Cloud Infrastructure (NCI). I would suggest that Nutanix Cloud Infrastructure (NCI) should develop their own P2V (physical to VM) tools instead of requiring users to rely on third-party solutions.

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Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"Cisco HyperFlex is helping us to put everything in centrally so that we can manage in one place."

"The compression and deduplication are very high. Therefore, we can use the size of the product more efficiently than other storage solutions."

"It is a hyper-converged solution which integrates with the network instead of the product."

"Cisco technical support is very skilled. From what I've had to access, there were quick responses and the necessary escalation."

"It allows us to authorize our residents to come in using their own personal devices to access any of our clinical applications and ensure that the PHI is secure and protected."

"With our four HyperFlex HX hosts (consisting of processor, memory, and disk), the performance is very fast and we have no problems at all. In all of the five years that we have been using HyperFlex, we haven't needed to increase our budget to buy additional hosts."

"Cisco HyperFlex HX has improved the way our organization functions on the storage side by having one big storage space for hosting VMs. We do not have to provision other ones. That's a positive aspect of it."

"Cisco offers very good quality."

More Cisco HyperFlex HX-Series [EOL] pros

"It has been stable so far."

"I definitely find the reduced power consumption very valuable."

"The snapshots, cloning, and replication are all effective in helping to reduce downtime. It can replicate cluster data for disaster recovery and it provides high availability in case a node or a disk fails."

"The product is easy to manage."

"Nutanix Acropolis AOS makes it easy to use and manage projects and it has a good reputation."

"It has seamless expandability."

"Scaling is very easy and no limitations are set."

"Their Google operating system is more mature, so their results are much better."

More Nutanix Cloud Infrastructure (NCI) pros

Cons

"Their technical support is very bad. We had an issue where instead of an engineer we got a PDF "doctor" that didn't know anything about our problem which was very frustrating."

"This solution is lacking in replication and backup abilities that I would like to see in a future release similar to HPE SimpliVity."

"The initial setup can be complex."

"Cisco is a bit more challenging in terms of deployment. The admin must be knowledgeable in order to complete the task. Without that knowledge, it will be difficult to complete."

"The initial setup of profiles and templates could be improved. Maybe some end profiles that you can use based on your type of deployment would be good."

"I haven't been too impressed with the Cisco HyperFlex HX, honestly. It's a hard concept."

"I would like to see them expand onto the cloud."

"The product does not have a cloud version...The product should be made more flexible in terms of integration capabilities."

More Cisco HyperFlex HX-Series [EOL] cons

"We would like to see a cloud version of Acropolis AOS. Currently, we're trying to implement an AWS environment for some solutions, but we would like to use another technology also to enhance our organization, so we are looking for another technology for this, especially a cloud solution."

"I feel like the flow chart and the automated processes have some room for improvement. They're nearly there, and the rest is fine. They've improved a lot over the past few years."

"It would be ideal if it was more secure."

"Areas for improvement would be the memory setting and the CPU setting reserve features, which are not available on Acropolis. I also feel that the DR solution, the reporting, and the component that is combined with the Nutanix OSP need to be improved."

"The new features are not free. You need to pay for each feature."

"Regarding third-party backup solutions, the only agentless option is Commvault, which is expensive, complex, and requires intensive vendor training."

"I'm not very technical, so I don't know if there are any features that are really lacking. Our customers seem pleased with it, and I haven't heard of any downsides."

"I'd like it to be more API-based."

More Nutanix Cloud Infrastructure (NCI) cons

Pricing and Cost Advice

"We currently have a perpetual license, which is kind of unlimited, so we don't have the normal licensing cost, yet."

"I would like a clearer licensing model. It should explain a bit more what you receive if you buy the more expensive license rather than the standard one."

"Cisco HyperFlex HX-Series is a bit pricier compared to other brands in the market...There is a need to make additional payments towards the maintenance and support of the solution."

"Cisco HyperFlex HX-Series is expensive. It's a standard license, and we pay for it yearly. I think we pay about 700."

"Our licensing is Hybrid. We have all of our applications for billing and outage management through this."

"One of the challenges we have with HyperFlex is that they have a subscription fee for the operating system that runs on it, and if I remember correctly, it costs approximately $15,000 USD per month."

"There is no additional licensing cost other than the cost for each part."

"HyperFlex is relatively expensive, but you get good value for money."

More Cisco HyperFlex HX-Series [EOL] pricing and cost advice

"The one disadvantage is relative, financially Nutanix Acropolis AOS is a little bit more expensive than the old solution."

"Many of my customers have issues with Acropolis' licensing model because they are charging the customers based on two things— the CPUs and the capacity in the solid stack disk — and that's a problem. Nutanix's competitors are not licensing that layer, so this is something that they should change. They should abandon this licensing model because it's too complex. Technical support is bundled with the subscription."

"It is not cheap, but if you look at the return on investment and the total cost of ownership, it is worth the price."

"I think it's cheaper than VMware in terms of cost."

"The product’s licensing fee is moderately expensive."

"Nutanix Acropolis AOS price includes no additional costs for features."

"This product is expensive, but they do have discounts. At one point, I saw that they were giving a 70% or 80% discount, which is a good thing, but maybe they should have a more realistic price and then a 5% to 10% discount."

"The software only licensing model is priced normally, but the licensing model that comes with hardware is priced very high. You can choose to pay the license yearly, or you can pay every three years, or every five years."

More Nutanix Cloud Infrastructure (NCI) pricing and cost advice

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Comparison Review

it_user244362

Managing Consultant with 51-200 employees

Aug 30, 2015

Nutanix vs. VMware EVO:RAIL vs. FlexPod

Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…

Read full review

Answers from the Community

Netanya Carmi

Content Manager at PeerSpot

Aug 2, 2022

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

See 2 answers

Leah Fainchtein Buenavida

Tech Blogger

Oct 17, 2021

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.

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Steffen Hornung

Administrator at Neuberger Gebäudeautomation GmbH

Aug 2, 2022

With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.

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Top Industries

By visitors reading reviews

Computer Software Company

12%

Educational Organization

Manufacturing Company

Financial Services Firm

Computer Software Company

13%

Manufacturing Company

Government

Financial Services Firm

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	24
Midsize Enterprise	17
Large Enterprise	57

By reviewers
Company Size	Count
Small Business	92
Midsize Enterprise	77
Large Enterprise	82

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...

See all answers

How does VxRail compare with Cisco HyperFlex HX Series?

VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...

See all answers

What makes Nutanix Cloud Infrastructure (NCI) worth using?

NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...

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Have you received reliable help from Nutanix Cloud Infrastructure's support when you contacted them?

NCI is one of the best out there. For any software, no matter how good it is, technical support makes it or breaks it for me. You may have an amazing product but if there is not anyone to help you ...

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Do you think Nutanix Cloud Infrastructure (NCI) is a secure solution?

Nutanix Cloud Infrastructure is a very secure solution and ensures this through its Flow Network Security feature. The platform establishes a foundation through a Zero Trust strategy that is compat...

See all answers

Comparisons

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Compared 14% of the time

VxRail vs Cisco HyperFlex HX-Series [EOL]

Compared 14% of the time

Dell PowerFlex vs Cisco HyperFlex HX-Series [EOL]

Compared 12% of the time

Sangfor HCI - Hyper Converged Infrastructure vs Cisco HyperFlex HX-Series [EOL]

Compared 12% of the time

HPE Alletra dHCI vs Cisco HyperFlex HX-Series [EOL]

Compared 10% of the time

More Cisco HyperFlex HX-Series [EOL] Competitors

VMware vSAN vs Nutanix Cloud Infrastructure (NCI)

Compared 8% of the time

VxRail vs Nutanix Cloud Infrastructure (NCI)

Compared 7% of the time

HPE SimpliVity vs Nutanix Cloud Infrastructure (NCI)

Compared 7% of the time

Sangfor HCI - Hyper Converged Infrastructure vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Azure Local vs Nutanix Cloud Infrastructure (NCI)

Compared 5% of the time

More Nutanix Cloud Infrastructure (NCI) Competitors

Product Reports

Buyer's Guide

Cisco HyperFlex HX-Series [EOL]

January 2026

Download Cisco HyperFlex HX-Series [EOL] product report

Buyer's Guide

Nutanix Cloud Infrastructure (NCI)

January 2026

Nutanix Cloud Infrastructure (NCI) report

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Also Known As

No data available

Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis

Overview

The Cisco HyperFlex HX Data Platform is a purpose-built, high-performance, scale-out file system with a wide array of enterprise-class data management services. The data platform’s innovations redefine distributed storage technology, giving you complete hyper-convergence with enterprise storage features:

Enterprise-class data management
Continuous data optimization
Securely encrypted storage
Dynamic data placement
Clusterwide parallel data distribution
Linear and incremental scaling
API-based data platform architecture
A simplified approach

Cisco

Nutanix Cloud Infrastructure delivers high performance and scalability with central management and one-click upgrades. It enhances data protection and reduces deployment complexities, perfect for businesses seeking efficient virtualization.

Nutanix Cloud Infrastructure offers a comprehensive platform integrating compute, storage, and network for optimal infrastructure management. It supports multiple hypervisors, offering flexibility, efficiency, and ease of use. With features like Prism for centralized management, organizations can manage resources effectively while benefiting from data protection enhancements such as deduplication and compression. Hyper-convergence enables seamless integration, reducing operational costs and increasing scalability. Though the pricing is high, and setup and administration can be complex, the ability to support hybrid cloud implementations and critical infrastructures like VDI and databases provides notable advantages.

What are the key features of Nutanix Cloud Infrastructure?

Prism for Centralized Management: Simplifies resource management with a single control interface.
High Performance: Offers efficient I/O operations to enhance processing efficiency.
Scalability: Easily adjusts to growing business needs with one-click upgrades.
Data Protection: Uses deduplication and compression for secure data handling.
Hyper-Convergence: Integrates compute, storage, and network to optimize infrastructure.
Multi-Hypervisor Support: Provides flexibility to choose preferred hypervisors.

What benefits should users look for in Nutanix Cloud Infrastructure?

Cost Effectiveness: Reduces operational costs through resource optimization.
Ease of Management: Centralized control enhances administrative efficiency.
Scalability: Grows seamlessly with business demand.
Data Protection: Increases security and reliability of data management.
Performance Improvement: Streamlines server provisioning and resource management.

Nutanix Cloud Infrastructure finds adoption across industries for virtualization, cloud services, and infrastructure consolidation. Organizations utilize it for hybrid clouds and virtual server hosting, supporting applications like databases and virtual desktop infrastructures. They report enhanced data protection, disaster recovery capabilities, and improved performance, facilitating effective resource management.

Nutanix

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest

St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.

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