Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

Cisco and Nutanix are both solutions in the HCI category. Additionally, 89% of Cisco users are willing to recommend the solution, compared to 94% of Nutanix users who would recommend it.

Cisco HyperFlex HX-Series [...

Read 90 Cisco HyperFlex HX-Series [EOL] reviews

89% willing to recommend

Nutanix Cloud Infrastructur...

Read 200 Nutanix Cloud Infrastructure (NCI) reviews

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7,893 Comparison Views

94% willing to recommend

Cisco HyperFlex HX-Series [...

Nutanix Cloud Infrastructur...

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Executive SummaryUpdated on Nov 2, 2025

Nutanix Cloud Infrastructure (NCI) and Cisco HyperFlex HX-Series are leaders in hyper-converged infrastructure solutions, competing in enterprise IT environments. NCI seems to have an edge in ease of management and cost-effectiveness, whereas HyperFlex stands out with its strong integration and high availability.

Features: NCI boasts high performance, ease of administration, and seamless integration with its distributed file system. Valued features include data protection, storage auto-tiering, and one-click upgrades. HyperFlex, however, integrates compute, storage, and network, excelling in its ability to integrate with Cisco’s network solutions and offers robust support for various hypervisors, with high availability being a notable strength.

Room for Improvement: NCI could improve network switch convergence, DRC solutions, and enhance built-in backup features, with demands for a more user-friendly interface. HyperFlex's scalability options require enhancement, along with integration tools for external solutions, and users have highlighted the high cost and complexity as deterrents. Better analytics and cloud integration would benefit HyperFlex further.

Ease of Deployment and Customer Service: NCI enables rapid deployment with its intuitive interface and outstanding technical support, consistently appreciated for responsiveness and expertise. HyperFlex's deployment, while effective, can seem complex, with a need for better guidance and documentation. Cisco’s comprehensive support is perceived as slightly less agile than Nutanix, affecting the customer service experience.

Pricing and ROI: NCI is seen as cost-effective, benefiting deployment and operational expenses through inclusive features and reduced infrastructure needs, contributing to faster ROI. Nutanix’s licensing simplicity is favored, albeit with notable upfront costs. HyperFlex, with a higher initial cost, is justified by its integrations and support, although annual subscription costs and licensing complexities suggest areas for improvement.

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January 2026

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Cisco HyperFlex HX-Series [...

Average Rating

8.0

Reviews Sentiment

6.7

Number of Reviews

Ranking in other categories

No ranking in other categories

Nutanix Cloud Infrastructur...

Average Rating

8.6

Reviews Sentiment

7.3

Number of Reviews

200

Ranking in other categories

Software Defined Storage (SDS) (6th), HCI (5th), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (4th)

Featured Reviews

reviewer2133501

Assistant VP, Information Technology at a financial services firm with 1,001-5,000 employees

Effective deduplication feature, but lacks a unified architecture

Cisco HyperFlex HX-Series could be improved by reducing the number of nodes. Currently, the architecture separates data, computing, memory, and storage into different parts. For example, if I need around 200 servers with a requirement of TB of storage, I would need 200 clusters, which can be quite cumbersome. Other solutions like Dell and Nutanix have a single combined unit that includes computing, memory, and storage, which can reduce the number of nodes required and also reduce licensing and power consumption. Therefore, I suggest improving the architecture of the Cisco HyperFlex HX-Series by combining computing, memory, and storage into a single unit, making it more efficient and easier to manage. It will also reduce the number of nodes required and licensing costs and help to reduce power consumption. I would like to see improved internal integration capabilities in the next release. Currently, it is constrained only to VMware only. So, there is no integration part of the RAC or IEL or anything, and it isn't easy to manage it. If I want to hold another partner, then that part will not be possible. So, you have to manage that particular integration. Another feature could be in terms of memory usage.

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Obasanjo Biliaminu

Head Systems Administration/Security at Nigeria Inter-Bank Settlement System PLC

Infrastructure efficiency has improved significantly with quick server provisioning, though physical to virtual migrations need a streamlined in-house tool

From my experience with Nutanix Cloud Infrastructure (NCI), there is one area that needs improvement. When moving a critical infrastructure from a physical machine to Nutanix Cloud Infrastructure (NCI), we currently have to use a third-party tool to convert the physical machine to a VM. We have to use VMware converter to perform this conversion before moving it to Nutanix Cloud Infrastructure (NCI). I would suggest that Nutanix Cloud Infrastructure (NCI) should develop their own P2V (physical to VM) tools instead of requiring users to rely on third-party solutions.

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Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"The flexibility is its most valuable feature; the ability to quickly deploy a number of help machines. It is not constrained by what we want to do."

"It has reduced the time it takes to put the servers in production by half the time."

"I love the Cisco design, the visual interface to manage and use the platform."

"The product is stable. No one complains about the stability, which is fabulous."

"The feature that we are most interested in is the scalability. When needed, we are able to add more nodes and scale it up further."

"It saves space for data centers, which is good."

"The price of the solution is good, especially when it comes to complex network solutions, such as UCS and Connect."

"Easy to spin up and operate virtual machines without the overhead of managing a storage network."

More Cisco HyperFlex HX-Series [EOL] pros

"Great flexibility and scalability."

"There are a lot of features in Nutanix that are different from other hyper-converged solutions, such as site-to-site replication. VM-based site-to-site replication is bundled with the software licensing. For the DR, it has the availability groups, which is one of the key features that Nutanix provides."

"It consolidates our servers, and improves our electricity consumption and cooling as well."

"The initial setup is straightforward."

"It is 100% stable. It's the most stable infrastructure that we have."

"We like that the size of the box is 1U or 2U only, and all the servers are fit into that box. The ease of operation is there. All the servers and the SAN storage are inside the box."

"The feature that I have found most valuable is its software Move, which we use to migrate virtual info from another platform to the Nutanix platform."

"The most valuable feature is the integration of all parts in Prism Element, the browser-based management tool."

More Nutanix Cloud Infrastructure (NCI) pros

Cons

"Lacks some integration and documentation could be improved."

"Technical support is very good. Not excellent, but good. There's still not enough data available on the web. For example, for the integration to VMware, I had a case recently and I searched for more information but didn't find any."

"I would rate the installation of Cisco HyperFlex HX-Series an eight out of ten. It can be complex."

"The architecture separates data, computing, memory, and storage into different parts."

"The setup was complex, especially since we usually do all the planning, sizing, and workflows before integration."

"Sometimes when there are multiple technologies involved in a support case, this is when there is a bit of a lag."

"If we compare it with VMware, the VMware product is basically very open, and it can be easily integrated with any platform. VMware product is also available on the cloud and is not an appliance-based product, whereas Cisco HyperFlex is an appliance-based product. Companies that want to use HCI as a platform or as a service would prefer something without an appliance. A SaaS-based product is better for a customer who is using the cloud and has multiple resources, workflows, and devices on the cloud and wants to go for a hyper-converged solution. This is where improvement is needed. In addition to an appliance-based product, Cisco should provide a SaaS-based product. Its price should be lower. Cisco needs to work on the pricing model for this product. Its price is a big road blocker when competing against Nutanix and VMware, which are its main competitors."

"One aspect that really needs to be looked at, is to fix the bugs issue."

More Cisco HyperFlex HX-Series [EOL] cons

"I believe that improvements could be made in regards to the DR in addition to deduplication and integration with others platforms. They also do not offer opportunities for network virtualization so it would be nice to see that in the future."

"The GUI for this solution needs improvement."

"If we can have certified compatibility with other companies, such as Oracle, then it would let us know that they function correctly together."

"I feel like the flow chart and the automated processes have some room for improvement. They're nearly there, and the rest is fine. They've improved a lot over the past few years."

"There is a lot of functionality in Prism Central, but sometimes you want to see those features in Prism Element."

"Nutanix Cloud Infrastructure's LTS version needs to be more reliable."

"In a hybrid cloud setup, we should be able to port our floors from on-premises to the public cloud and from the public cloud to on-premises."

"Regarding third-party backup solutions, the only agentless option is Commvault, which is expensive, complex, and requires intensive vendor training."

More Nutanix Cloud Infrastructure (NCI) cons

Pricing and Cost Advice

"The price is a bit high. It could be better, but the product is worth the cost."

"The pricing is a bit expensive."

"Our licensing is Hybrid. We have all of our applications for billing and outage management through this."

"There is a license required to use this solution."

"Cisco is quite expensive, but not in the initial first buy."

"The price is a bit too high."

"We would not have invested if we didn't feel the return was there for our customers."

"The product is expensive. Other solutions are cheaper."

More Cisco HyperFlex HX-Series [EOL] pricing and cost advice

"I would rate the price seven out of ten with ten being the most expensive."

"It is less expensive than the VMware alternative."

"The cost of Nutanix Acropolis AOS is reasonable."

"Nutanix price is high because it bundles all the components into single deals rather than allowing you to select the features that you want/will use."

"The solution could be a little less expensive."

"Nutanix Cloud Infrastructure could be cheaper. It's costly to upgrade the solution. There are no additional costs aside from the license."

"Nutanix Cloud Infrastructure is expensive."

"The product’s licensing fee is moderately expensive."

More Nutanix Cloud Infrastructure (NCI) pricing and cost advice

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Comparison Review

it_user244362

Managing Consultant with 51-200 employees

Aug 30, 2015

Nutanix vs. VMware EVO:RAIL vs. FlexPod

Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…

Read full review

Answers from the Community

Netanya Carmi

Content Manager at PeerSpot

Aug 2, 2022

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

See 2 answers

Leah Fainchtein Buenavida

Tech Blogger

Oct 17, 2021

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.

Read full answer

Steffen Hornung

Administrator at Neuberger Gebäudeautomation GmbH

Aug 2, 2022

With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.

Read full answer

Top Industries

By visitors reading reviews

Marketing Services Firm

14%

Computer Software Company

10%

Educational Organization

Manufacturing Company

Computer Software Company

12%

Manufacturing Company

Financial Services Firm

Government

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	24
Midsize Enterprise	17
Large Enterprise	57

By reviewers
Company Size	Count
Small Business	92
Midsize Enterprise	77
Large Enterprise	82

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...

See all answers

How does VxRail compare with Cisco HyperFlex HX Series?

VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...

See all answers

What makes Nutanix Cloud Infrastructure (NCI) worth using?

NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...

See all answers

Have you received reliable help from Nutanix Cloud Infrastructure's support when you contacted them?

NCI is one of the best out there. For any software, no matter how good it is, technical support makes it or breaks it for me. You may have an amazing product but if there is not anyone to help you ...

See all answers

Do you think Nutanix Cloud Infrastructure (NCI) is a secure solution?

Nutanix Cloud Infrastructure is a very secure solution and ensures this through its Flow Network Security feature. The platform establishes a foundation through a Zero Trust strategy that is compat...

See all answers

Comparisons

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VxRail vs Cisco HyperFlex HX-Series [EOL]

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Sangfor HCI - Hyper Converged Infrastructure vs Cisco HyperFlex HX-Series [EOL]

Compared 9% of the time

HPE Alletra dHCI vs Cisco HyperFlex HX-Series [EOL]

Compared 8% of the time

More Cisco HyperFlex HX-Series [EOL] Competitors

VMware vSAN vs Nutanix Cloud Infrastructure (NCI)

Compared 9% of the time

VxRail vs Nutanix Cloud Infrastructure (NCI)

Compared 7% of the time

HPE SimpliVity vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Sangfor HCI - Hyper Converged Infrastructure vs Nutanix Cloud Infrastructure (NCI)

Compared 5% of the time

Azure Local vs Nutanix Cloud Infrastructure (NCI)

Compared 5% of the time

More Nutanix Cloud Infrastructure (NCI) Competitors

Product Reports

Buyer's Guide

Cisco HyperFlex HX-Series [EOL]

February 2026

Download Cisco HyperFlex HX-Series [EOL] product report

Buyer's Guide

Nutanix Cloud Infrastructure (NCI)

January 2026

Nutanix Cloud Infrastructure (NCI) report

Download Nutanix Cloud Infrastructure (NCI) product report

Also Known As

No data available

Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis

Overview

The Cisco HyperFlex HX Data Platform is a purpose-built, high-performance, scale-out file system with a wide array of enterprise-class data management services. The data platform’s innovations redefine distributed storage technology, giving you complete hyper-convergence with enterprise storage features:

Enterprise-class data management
Continuous data optimization
Securely encrypted storage
Dynamic data placement
Clusterwide parallel data distribution
Linear and incremental scaling
API-based data platform architecture
A simplified approach

Cisco

Nutanix Cloud Infrastructure delivers high performance and scalability with central management and one-click upgrades. It enhances data protection and reduces deployment complexities, perfect for businesses seeking efficient virtualization.

Nutanix Cloud Infrastructure offers a comprehensive platform integrating compute, storage, and network for optimal infrastructure management. It supports multiple hypervisors, offering flexibility, efficiency, and ease of use. With features like Prism for centralized management, organizations can manage resources effectively while benefiting from data protection enhancements such as deduplication and compression. Hyper-convergence enables seamless integration, reducing operational costs and increasing scalability. Though the pricing is high, and setup and administration can be complex, the ability to support hybrid cloud implementations and critical infrastructures like VDI and databases provides notable advantages.

What are the key features of Nutanix Cloud Infrastructure?

Prism for Centralized Management: Simplifies resource management with a single control interface.
High Performance: Offers efficient I/O operations to enhance processing efficiency.
Scalability: Easily adjusts to growing business needs with one-click upgrades.
Data Protection: Uses deduplication and compression for secure data handling.
Hyper-Convergence: Integrates compute, storage, and network to optimize infrastructure.
Multi-Hypervisor Support: Provides flexibility to choose preferred hypervisors.

What benefits should users look for in Nutanix Cloud Infrastructure?

Cost Effectiveness: Reduces operational costs through resource optimization.
Ease of Management: Centralized control enhances administrative efficiency.
Scalability: Grows seamlessly with business demand.
Data Protection: Increases security and reliability of data management.
Performance Improvement: Streamlines server provisioning and resource management.

Nutanix Cloud Infrastructure finds adoption across industries for virtualization, cloud services, and infrastructure consolidation. Organizations utilize it for hybrid clouds and virtual server hosting, supporting applications like databases and virtual desktop infrastructures. They report enhanced data protection, disaster recovery capabilities, and improved performance, facilitating effective resource management.

Nutanix

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest

St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.

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