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Cisco SecureX [EOL] vs Microsoft Defender XDR comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Endpoint Detection and Response (EDR) (5th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco SecureX [EOL]
Average Rating
9.0
Reviews Sentiment
8.2
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Microsoft Defender XDR
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Endpoint Detection and Response (EDR) (9th), Extended Detection and Response (XDR) (5th), Microsoft Security Suite (4th)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Dene Lewis - PeerSpot reviewer
Head of Technical Strategy and Direction CAE Technology Services Ltd at CAE Technology Services Limited
A scalable SaaS based platform that helps with cyber threat intelligence and automated hunting
I would rate Cisco SecureX a ten out of ten. I find the product to be a fantastic platform. If you are eligible, start using it straight away. The best way to evaluate it is to start using it and see where it fits within your organization. I think it helps our customers really deliver their SecOps goals, and I see it as a core foundation of CAE's own security strategy going forward. Our partnership with Cisco is one that was built on trust over a long period of time. This has enabled us to work together to be able to provide the solutions that our customers need to drive their organizations forward. The value we add as a reseller is being able to work closer with our customers, understand them, and get intimate with their organizations. That enables us to offer them the right solutions that will help them achieve their goals.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable feature is that you can select remote access of any machine for sandboxing."
"I like the centralized console and the predictive analysis it does of malware. It is very stable and also scalable."
"We can visualize and control the activities in the environment from anywhere."
"Cortex XDR by Palo Alto Networks is easy to use and does not consume a lot of hardware resources."
"One of the main benefits of the solution is its intelligence to correlate the events into an incident."
"We can use Cortex XDR to get the entire graph of the incidents from source to destination, and we can take remedial action."
"The solution allows control over the user and his machine through Cortex XDR security policies."
"After installing this solution, it identified, blocked, and provided the complete attack chain, which was very helpful."
"When it comes as a business bundle, we come to customers to provide a one-stop shop, and we provide a return of value on human resources, with an XDR SecureX platform offer that customers love."
"SecureX enables us to have all the threat intelligence and threat event data in one place."
"Using SecureX, a tool provided by Cisco, we can easily integrate it with many of our other Cisco products such as Cisco ISE and many networking devices."
"It has evolved a lot, just that monitoring piece to the current Orchestrator piece. The additional analytics are there. They now have something called Insight, which can basically take data from Microsoft Azure AD and Intune to give us information about our endpoints. This is detailed information about the endpoints, from Secure Endpoint and all these different products. So, it is just constantly evolving. Every time that it evolves, we have more information with more visibility. There are more features that we have that just make everything so much easier, and it is in one place. I don't have to keep going back and forth. I don't have to go to Secure Endpoint and ISE to get the data. I don't have to go to Intune on Microsoft to get the information. It is all in one place."
"This solution definitely helps us meet our cyber security goals and we haven't had any problems so far."
"Our customers find the product's third-party integrations valuable. Our customers are also impressed with the tool's capability to pick up third-party threat feeds and use that as part of the decision-making process."
"The forensics are amazing because when you have enrichment, and the solutions talk with each other, when you need it, you have the ability to know everything in the organization: when, why, whatever."
"The SecureX solution has the best impact for the customer because it has all the visibility of my applications and my users' applications."
"I like Defender XDR's reports and alerts. They give you updates about the latest hotfixes and zero-day vulnerabilities, which gives me all the information I need to maintain my servers."
"Microsoft Defender XDR is very comprehensive, covering a lot of the services, tools, and applications that we use, so it's very efficient, and it works out of the box."
"Microsoft Defender XDR's capability to automatically disrupt advanced cyber attacks is very effective."
"Among the most valuable features are the alert timeline, the alert story, which is pretty detailed. It gives us complete insight into what exactly happened on the endpoint. It doesn't just say, "Malware detected." It tells us what caused that malware to be detected and how it was detected. It gives us a complete timeline from beginning to end."
"The most valuable feature is the DLP because that's where we can have an added data protection layer and extend it not just to emails but to the documents that users are working on. We can make sure that sensitive data is tagged and flagged if unauthorized parties are using it."
"For technical support, I would definitely give a rating of nine out of ten."
"We use Microsoft 365 Defender to help secure threats of the Office package, such as Word, Excel, and PowerPoint, and additionally, it can fix issues."
"One of the most valuable features of Microsoft Defender XDR is its ability to provide preemptive reports regarding excessive privileged access."
 

Cons

"It would be better if they could educate the customers more. Some sort of seminars and roadshows will help educate the customers and show what the product can do. The price could be better. It would also help if they had a team for deployment and support."
"Cortex XDR by Palo Alto Networks is a very good product, but financially, it is very expensive, so the company should look into that area."
"Cortex XDR by Palo Alto Networks can improve mobile integration to allow access to the console."
"It's not an ideal choice for smaller businesses, as you need a minimum of 200 endpoints to even use the solution at all."
"I would like to see some additional features related to email protection included."
"Cortex XDR by Palo Alto Networks could improve by adding a sandbox feature to better compete with their competitors which have it."
"Technology evolves every day, so it would be nice if it gets more secure. It can also have more integration with other platforms."
"One thing that was missing was the integration part. Currently, they don't have out-of-box integration with IBM QRadar, or if they have the integration, the integration doesn't work well."
"They could expand into more areas."
"Remediation stuff could be integrated into the product's automation."
"The automation and orchestration could be simpler."
"It is good that it provides information. However, I think that there needs to be more actionable items for us based on the information provided."
"The playbooks provided with the product are great, although I would appreciate having more playbooks available. Threats are constantly evolving, so having access to updated playbooks is crucial."
"I'm not sure that I would call it a bug, but sometimes the solution is a little slow."
"One of the improvements the product needs is more integration with collaboration platforms."
"They could put in more third-party [integrations]... also more playbooks, out-of-the-box, for automation [would be helpful]."
"The documentation on their website is somewhat outdated and doesn't show properly. I wanted to try a query in Microsoft Defender 365. When I opened the related documentation from the security blog on the Microsoft website, the figures were not showing. It was difficult to understand the article without having the figures. The figures were there in the article, but they were not getting loaded, which made the article obsolete."
"These days, in the security industry, there is a buzzword called zero trust. I personally have not seen much evidence of how Defender can enhance the story of Zero Trust for enterprises."
"The capability to not only thwart attacks but also to adapt to evolving threats is crucial."
"The initial time spent setting up and configuring Defender XDR is a bit longer than the other solutions. If everything were on one portal, the platforms for managing policies or alerts would be simpler. We must automate and manage policies on Intune rather than the same portal."
"Some of our older hardware experienced a slight bump in CPU and memory usage. Although I don't have empirical data to back that up, I would suggest possibly more streamlining in the software."
"The solution can improve the rules and privileges it offers."
"The web filtering solution needs to be improved because currently, it is very simple."
"There are a few technical issues with Defender XDR that can be improved. Sometimes, the endpoint devices are not reporting properly to the Defender 365 portal. When you're getting all the information from the Microsoft portal, the devices are sometimes not in sync. We have hundreds of endpoint devices, some needing to be onboarded again."
 

Pricing and Cost Advice

"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"Our customers have expressed that the price is high."
"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"Licensing for Palo Alto Networks Cortex XDR can be costly, especially when it comes to a hundred users. A license is required for each user, and the subscription must be renewed on a yearly basis."
"When we first bought it, it was a bit expensive, but it was worth it. The licensing was straightforward."
"If one wishes to work with another team or large number of users at a future point, he must purchase a license for them."
"I feel it is fairly priced."
"It's about $55 per license on a yearly basis."
"The pricing is the best part of this solution. It is free if you buy Umbrella or Duo Security. It is also a good solution."
"The pricing is competitive, especially for education institutions. Licensing can be a little bit difficult to navigate, especially with resellers with Cisco, but for us it has been pretty easy."
"It is free. It can't get any better than that."
"For the value you get, the pricing of the solution is excellent."
"Cisco SecureX is more expensive than Trend Micro. However, considering the integration capabilities with other solutions and the quality of technical support, I believe there's justification for the price difference."
"The product is absolutely free to any customer. As such, the only thing one must keep in mind is that as long as he already has one Cisco security product, irregardless of what that product is, SecureX is available for free."
"You can spend less money for another solution, but if you really want to have a good solution you have to pay. We are happy that we are getting such a good solution for what we are spending."
"It comes free with all Cisco products. So, it is a good price."
"The functionality is fantastic, but for medium and small-sized companies it's overpriced. It would be better if it were a little bit cheaper."
"For Defender, they have Endpoint Plan 1 and Endpoint Plan 2, but I don't know on what basis they have classified Endpoint Plan 1 and Plan 2, but it has given me enough pain to pick and design Endpoint Plan 1 or Endpoint Plan 2 for my organization. In fact, we are still struggling with it. Too many SKUs are confusing. There should not be too many SKUs, and they shouldn't charge for every new feature."
"Microsoft is not competitive with the pricing of the solution. The competitors are able to offer lower discounts. The price of the solution is higher."
"The price of the solution is high compared to others and we have lost some customers because of it."
"They have moved from a licensing model to pay-per-use... The question is: What happens if, for any reason, there's not enough budget to accept this model? That could be a great problem."
"It has consistently offered highly appealing academic pricing, with distinct rates for higher education and general educational purposes."
"Microsoft Defender XDR is already included in our Office 365 licensing. It is better because we're saving money by using it."
"Understanding the subscription model has been a bit challenging, as every feature or requirement comes with an additional cost."
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Financial Services Firm
9%
Outsourcing Company
24%
Construction Company
14%
Marketing Services Firm
8%
Comms Service Provider
6%
Financial Services Firm
9%
Computer Software Company
8%
Outsourcing Company
8%
Comms Service Provider
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise7
Large Enterprise3
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
 

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What is your experience regarding pricing and costs for Microsoft 365 Defender?
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What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
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Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Kenna.AppSec, Kenna.VI
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
NHS, Rackspace, UNC Pembroke, University of North Carolina at Charlotte, Missing Piece
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Find out what your peers are saying about SentinelOne, TrendAI, Wazuh and others in Extended Detection and Response (XDR). Updated: September 2026.
913,806 professionals have used our research since 2012.