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Cisco SecureX [EOL] vs Microsoft Defender XDR comparison

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Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
108
Ranking in other categories
Endpoint Protection Platform (EPP) (5th), Endpoint Detection and Response (EDR) (7th), Extended Detection and Response (XDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (2nd)
Cisco SecureX [EOL]
Average Rating
9.0
Reviews Sentiment
8.2
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Microsoft Defender XDR
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
107
Ranking in other categories
Endpoint Detection and Response (EDR) (8th), Extended Detection and Response (XDR) (4th), Microsoft Security Suite (4th)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Dene Lewis - PeerSpot reviewer
Head of Technical Strategy and Direction CAE Technology Services Ltd at CAE Technology Services Limited
A scalable SaaS based platform that helps with cyber threat intelligence and automated hunting
I would rate Cisco SecureX a ten out of ten. I find the product to be a fantastic platform. If you are eligible, start using it straight away. The best way to evaluate it is to start using it and see where it fits within your organization. I think it helps our customers really deliver their SecOps goals, and I see it as a core foundation of CAE's own security strategy going forward. Our partnership with Cisco is one that was built on trust over a long period of time. This has enabled us to work together to be able to provide the solutions that our customers need to drive their organizations forward. The value we add as a reseller is being able to work closer with our customers, understand them, and get intimate with their organizations. That enables us to offer them the right solutions that will help them achieve their goals.
KO
House security operator at Cypress Creek Renewables
Advanced threat hunting saves significant time in tracking and responding to incidents
Microsoft Defender XDR could be improved with a lower price. My main suggestion would essentially be what Copilot is providing, which is a single pane of glass, so I don't have to go to different windows. That's just a workflow consideration for me. It would be great to have all the information centralized into one particular data app. If I need to open up extra ones, I can, however, I would appreciate a future where everything I need is right there on one single pane of glass. Beyond that, there's really nothing else I see that I would want Microsoft to improve.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"They have a new GUI which is just fantastic."
"The solution allows us to make investigations. Other XDR solutions also provide similar capabilities but for investigation, Cortex XDR is better."
"After deploying Traps, we saw the performance of the network improve by 65 to 70 percent."
"The positive impacts I see from Cortex XDR by Palo Alto Networks include a complete 360-degree view of our security posture altogether, being a uniform platform where we are ingesting logs from multiple resources."
"It'll not slow down your system when compared to others."
"Cortex XDR is a simple platform that's easy for administrators and users. You have a lot of flexibility to change or customize the features."
"Cortex XDR is stable, offering high quality and reliable performance."
"After installing this solution, it identified, blocked, and provided the complete attack chain, which was very helpful."
"Using SecureX, a tool provided by Cisco, we can easily integrate it with many of our other Cisco products such as Cisco ISE and many networking devices."
"I like that I don't have to jump around to five different products and log into five different places to view the data that it returns."
"SecureX enables us to have all the threat intelligence and threat event data in one place."
"It has evolved a lot, just that monitoring piece to the current Orchestrator piece. The additional analytics are there. They now have something called Insight, which can basically take data from Microsoft Azure AD and Intune to give us information about our endpoints. This is detailed information about the endpoints, from Secure Endpoint and all these different products. So, it is just constantly evolving. Every time that it evolves, we have more information with more visibility. There are more features that we have that just make everything so much easier, and it is in one place. I don't have to keep going back and forth. I don't have to go to Secure Endpoint and ISE to get the data. I don't have to go to Intune on Microsoft to get the information. It is all in one place."
"One of the most valuable features is the simplicity of deploying SecureX. It's very easy to do that and then you gain very detailed visibility into everything that's going on in your network and, obviously, at the device level. There's just a wealth of information that you can pull from all of these products that are part of SecureX. You know exactly if you have an issue or not."
"The automation and orchestration tools are the most valuable features."
"The most beneficial feature of Cisco SecureX for cybersecurity efforts is its integration with other Cisco solutions and the environment. This sets it apart, as its APIs and overall integration capabilities are very strong. Additionally, its detection capabilities are commendable."
"The most valuable feature is its ability to manage all the applications and visibility. For example, if there is malware, spam, or another component that wants to attack the company in my servers, network, or applications, then SecureX will react to the problem."
"The most valuable features are machine learning, AI, and auto-remediation of none malicious alerts."
"The portal is quite user-friendly. There is integration with Office, Intune, and other products from the same portal. From there, we can see which policies are installed on a particular machine. We also can manage devices, groups, and tagging."
"You can configure the product very easily."
"The incident threat response and its ability to facilitate effective remediation against threats are the standout features."
"We are able to consolidate licences and make use of many Microsoft products using this solution. If we have any Microsoft customers, we encourage them to use this solution for enterprise defence."
"Within advanced threat hunting, the tables that have already been defined by Microsoft are helpful. In the advanced threat hunting tab, there were different tables, and one of the tables was related to device info, device alert, and device events. That was very helpful. Another feature that I liked but didn't have access to was deep analysis."
"I like Defender XDR's automation capabilities. XDR isn't automated by default, but you can automate it to respond. If an attack is performed anywhere within the organization, you can isolate that instance from the network. This is what I can figure out for it. When integrated with Sentinel, you can set up playbooks to automate all the alerts gathered on Sentinel from different Microsoft solutions. Sentinel has a wider range of capabilities than XDR."
"The most valuable aspect is undoubtedly the exploration capability"
 

Cons

"Cortex XDR by Palo Alto Networks could improve by adding a sandbox feature to better compete with their competitors which have it."
"It is an enterprise-level solution. Its price could be less expensive."
"The solution lacks real-time, on-demand antivirus."
"Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth."
"I would like to see some additional features related to email protection included."
"Cortex XDR by Palo Alto Networks can improve mobile integration to allow access to the console."
"The encryption is not up to the mark."
"The main issue I could point out is the offline agents and the way that it is missing."
"The front-end work controls the new algorithm and the firewall rules. The search feature of these rules could be improved."
"I'm not sure that I would call it a bug, but sometimes the solution is a little slow."
"what's missing right now is the multi-tenant capability."
"If they could make the Cisco Umbrella piece a little bit more advanced or easier to manage, that would help. We use it for filtering and when you compare it to a normal content filter, it lacks some functionality."
"One of the improvements the product needs is more integration with collaboration platforms."
"Remediation stuff could be integrated into the product's automation."
"They could expand into more areas. The more third-parties that we have tied into it, the better. The capabilities are there. As they just continue to involve the product, the more things that you can look into, then the more analytics that you can get. Also, the more data that we can get, then the better off we will be."
"The playbooks provided with the product are great, although I would appreciate having more playbooks available. Threats are constantly evolving, so having access to updated playbooks is crucial."
"The abundance of sub-dashboards and sub-areas within the main dashboard can be confusing, even if it all technically makes sense."
"There is no comprehensive visibility, making it less user-friendly."
"At times, when we have an incident email and we click on the link for that incident, it opens a pop-up, but there is nothing. It has happened a couple of times."
"Defender's AI for identifying suspicious activity could be improved. Also, I do a lot of home updates. Maybe there is a way to set it up faster. For example, let's say that I want to automatically update seven computers, servers, etc. I wouldn't do it to a user, but maybe the server. I don't mind if the server restarts automatically."
"Microsoft Defender is slow to adapt to evolving threats."
"There are a few technical issues with Defender XDR that can be improved. Sometimes, the endpoint devices are not reporting properly to the Defender 365 portal. When you're getting all the information from the Microsoft portal, the devices are sometimes not in sync. We have hundreds of endpoint devices, some needing to be onboarded again."
"We struggle sometimes with tier one support agents who give canned responses."
"The documentation on their website is somewhat outdated and doesn't show properly. I wanted to try a query in Microsoft Defender 365. When I opened the related documentation from the security blog on the Microsoft website, the figures were not showing. It was difficult to understand the article without having the figures. The figures were there in the article, but they were not getting loaded, which made the article obsolete."
 

Pricing and Cost Advice

"It's way too expensive, but security is expensive. You pay for your licensing, and then you pay for someone to monitor the stuff."
"The cost depends on your chosen license type, like Pro or other licenses."
"The pricing is a little high. It is per user per year."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"The solution has one subscription for endpoint protection and one subscription for detection and response. The two licenses combined give you the BRO version."
"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"Licensing for Palo Alto Networks Cortex XDR can be costly, especially when it comes to a hundred users. A license is required for each user, and the subscription must be renewed on a yearly basis."
"It would be nice if they had a different pricing model. Most of our budget for projects goes towards Cisco."
"You can spend less money for another solution, but if you really want to have a good solution you have to pay. We are happy that we are getting such a good solution for what we are spending."
"The pricing is competitive, especially for education institutions. Licensing can be a little bit difficult to navigate, especially with resellers with Cisco, but for us it has been pretty easy."
"For the value you get, the pricing of the solution is excellent."
"It comes free with all Cisco products. So, it is a good price."
"Cisco SecureX is more expensive than Trend Micro. However, considering the integration capabilities with other solutions and the quality of technical support, I believe there's justification for the price difference."
"The product is absolutely free to any customer. As such, the only thing one must keep in mind is that as long as he already has one Cisco security product, irregardless of what that product is, SecureX is available for free."
"It is free. It can't get any better than that."
"The license cost for a year is approximately forty-four thousand, and this annual saving is a significant factor in our decision to switch."
"It is fairly priced because we get complete integrated services with the E5 license."
"The pricing of Microsoft 365 Defender is definitely on the costly side, but with the features and services that Microsoft provides, such as the seamless integration of all the Defender tools, while the price is on the higher side, there is no alternative."
"It has consistently offered highly appealing academic pricing, with distinct rates for higher education and general educational purposes."
"I believe that the pricing of the licensing is fair."
"Microsoft 365 Defender offers competitive pricing."
"The bundling of software makes it easier to manage our setup, but Microsoft purposefully obfuscates this through marketing ploys to hide costs."
"Microsoft Defender XDR is already included in our Office 365 licensing. It is better because we're saving money by using it."
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Top Industries

By visitors reading reviews
Computer Software Company
9%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Computer Software Company
19%
Marketing Services Firm
11%
Government
8%
Outsourcing Company
7%
Computer Software Company
12%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business44
Midsize Enterprise20
Large Enterprise47
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise7
Large Enterprise3
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise26
Large Enterprise39
 

Questions from the Community

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Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
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What do you like most about Microsoft 365 Defender?
Microsoft Defender XDR provides strong identity protection with comprehensive insights into risky user behavior and p...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with pricing, setup, costs, and licensing of Microsoft Defender XDR is tied to our E5 subscription, whi...
What needs improvement with Microsoft 365 Defender?
I am not aware of a mobile app that would be available for my team. With a single analyst, if she is ever away, it wo...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Kenna.AppSec, Kenna.VI
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
NHS, Rackspace, UNC Pembroke, University of North Carolina at Charlotte, Missing Piece
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Find out what your peers are saying about CrowdStrike, SentinelOne, TrendAI and others in Extended Detection and Response (XDR). Updated: February 2026.
884,933 professionals have used our research since 2012.