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Microsoft Defender for Endpoint vs VirusTotal comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Anti-Malware Tools
1st
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Advanced Threat Protection (ATP) (5th), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
VirusTotal
Ranking in Anti-Malware Tools
5th
Average Rating
8.8
Reviews Sentiment
7.3
Number of Reviews
10
Ranking in other categories
Threat Intelligence Platforms (TIP) (7th)
 

Mindshare comparison

As of August 2026, in the Anti-Malware Tools category, the mindshare of Microsoft Defender for Endpoint is 6.3%, down from 15.1% compared to the previous year. The mindshare of VirusTotal is 3.1%, down from 4.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Anti-Malware Tools Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.3%
VirusTotal3.1%
Other90.6%
Anti-Malware Tools
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
reviewer2588199 - PeerSpot reviewer
Security Specialist at a tech vendor with 10,001+ employees
Improves security alerts and analysis with comprehensive insights
I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the category of websites. The addition of a file selection option to analyze files would also enhance the service.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Microsoft Defender for Endpoint has helped free up our SOC team to work on other projects or tasks."
"The investigation aspect is the most useful. It's user friendly and has a good user interface."
"The most likable feature of Microsoft Defender for Endpoint is the sheer number of features and data it provides."
"We have not had any attacks, in terms of viruses, worms, or ransomware, in the last three years."
"Microsoft Defender for Endpoint's WCS function, a content filtering solution, has proven to be the most useful, stable, and reliable option for our current needs."
"We found that because the endpoint devices are based on Microsoft Windows devices and Windows Defender is integrated with the foundation and the core layer, it makes it more integrated and more agile in terms of responding to any security threats or changes or development."
"Microsoft's technical support is fantastic."
"The visibility into threats that the solution provides is pretty awesome... This is something that makes me think, "Wow, okay. If I had my own organization, I would probably get this too." It stops the threat before an employee gets phished or something gets downloaded to their computer."
"It can scan the dark web and find if an email ID has been compromised. This is another area that we have not explored yet."
"The most valuable feature is the worldwide malware information database."
"It allows us to see if there have been previous reports on certain indicators of compromise, providing insights from other security professionals."
"The product is easy to use with coding, such as Python or Java, via its API."
"It is quite simple for anyone if they just want to check some suspicious URLs."
"It provides detailed insights into possible malicious behavior, dropped files, and TCP connections."
"I have never had any problems with stability or bugs while using VirusTotal."
"With VirusTotal, I can check for any hash, malware, file, domain, IP URL, or malicious URL, and Kaspersky stays clean."
 

Cons

"Our team's knowledge of the solution needs to be improved, and Microsoft could do a better job conveying the necessary information to users. We could proactively use the tool more and explore capabilities we are not yet utilizing."
"There are alternative solutions that offer a greater range of dashboard insights when compared to Microsoft Defender for Endpoint."
"The most problematic part of this program is the difficult customer service."
"More integration with different platforms is an area for improvement for this product, and should be included in its next release."
"There's scanning going on that occasionally topples the memory, causing everything to freeze. This should be fixed."
"The product should reduce updates since it is hard to keep up."
"It is inexpensive but could be cheaper like anything else."
"The biggest issue I had with Microsoft Defender for Endpoint was the antivirus and ransomware. I wanted central visibility over all the machines that we operate."
"There should be room for improvement, particularly in the API side of things."
"VirusTotal needs better advertisement and promotion, especially in the Middle East, since it is not yet widely recognized or popular in that region."
"I would like to see improvements in the score consistency and accuracy."
"I would like to see improved correlation with other threat intelligence sources, not just reliant on its own database, to enhance the database of threat intelligence that VirusTotal offers."
"The platform could improve in the areas of endpoints and networks."
"There is room for improvement, particularly in making some of the most useful features more accessible in the non-paid version."
"VirusTotal is hard to understand because you need to know Google Docs to create queries, and it doesn't have documentation for that."
"VirusTotal has predefined reports, but there is a lot of manual effort involved."
 

Pricing and Cost Advice

"It is affordable and comes in the Office 365 bundle."
"Because Microsoft Defender comes as an add-on, it can be a bit expensive if you're trying to buying it separately. Another option is to upgrade, but the enterprise licenses for Microsoft can also be quite a bit pricey. Overall, the cost of Microsoft Defender compared to that of other endpoint detection solutions is slightly higher."
"The solution comes as part of Microsoft Windows."
"Microsoft has different plans for buying this product. The price depends on the configuration of the full set of products that you buy and on the licensing program in your contract."
"The solution is free and comes with Windows."
"The license cost is around $35 per machine, which is not expensive compared to other products."
"If you don't purchase the advanced threat protection then there is no additional charge."
"It came with Windows."
"The pricing is reasonable."
"VirusTotal is an expensive solution."
"We are using VirusTotal with free licenses, managing the license limits across three or four accounts, thus incurring no costs."
"The pricing is very economical."
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Top Industries

By visitors reading reviews
Manufacturing Company
10%
Financial Services Firm
9%
Computer Software Company
8%
Comms Service Provider
8%
Computer Software Company
12%
Financial Services Firm
10%
Comms Service Provider
10%
Manufacturing Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise2
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What is your experience regarding pricing and costs for VirusTotal?
I do not know about the pricing or licensing as our organization services VirusTotal for our clients.
What needs improvement with VirusTotal?
I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the categ...
What is your primary use case for VirusTotal?
As I work in an incident response role, my daily task is to mitigate the security alert and perform the analysis part. When any alerts come, I check the IPs from where they originate and the locati...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Information Not Available
Find out what your peers are saying about Microsoft Defender for Endpoint vs. VirusTotal and other solutions. Updated: June 2026.
908,834 professionals have used our research since 2012.