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Microsoft Defender for Endpoint vs VirusTotal comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Anti-Malware Tools
1st
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Advanced Threat Protection (ATP) (4th), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
VirusTotal
Ranking in Anti-Malware Tools
5th
Average Rating
8.8
Reviews Sentiment
7.3
Number of Reviews
10
Ranking in other categories
Threat Intelligence Platforms (TIP) (6th)
 

Mindshare comparison

As of September 2026, in the Anti-Malware Tools category, the mindshare of Microsoft Defender for Endpoint is 6.0%, down from 14.1% compared to the previous year. The mindshare of VirusTotal is 3.0%, down from 4.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Anti-Malware Tools Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.0%
VirusTotal3.0%
Other91.0%
Anti-Malware Tools
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
reviewer2588199 - PeerSpot reviewer
Security Specialist at a tech vendor with 10,001+ employees
Improves security alerts and analysis with comprehensive insights
I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the category of websites. The addition of a file selection option to analyze files would also enhance the service.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Microsoft Defender for Endpoint comes pre-installed in Microsoft Windows."
"Defender provides useful alerts and groups them. It sends an alert to your portal if it detects any malicious activity, and you can group multiple alerts to form an incident."
"Microsoft Defender for Endpoint is a robust platform."
"You can query and access useful information from logs and events, which is powerful and efficient."
"We had certain compliance and usage issues. For example, our company wanted to go with CIS, but we didn't have a proper way of measuring whether the endpoints have the right standards in place or whether they were compliant with CIS. Microsoft Defender was like a one-stop for most things because it gave us the vulnerability and patching scores so that our vulnerability management teams can focus on covering up the vulnerabilities and the patching team can check the vulnerable versions and deploy the right versions."
"The initial setup is not difficult or complex; it's very simple and straightforward."
"The advanced threat protection has a large cloud presence in Azure that we can take advantage of, and they update their product frequently."
"Microsoft Defender for Endpoint has helped free up my SOC team to work on other projects and tasks, and the automated reporting and dashboarding has saved them a lot of time, amounting to several man-hours."
"It allows us to see if there have been previous reports on certain indicators of compromise, providing insights from other security professionals."
"VirusTotal provides 95% to 98% accurate information."
"The feature I like the most is the ability to see the MD5 or SHA-256 signature of the file, and also the composition of the file according to its segments."
"With VirusTotal, I can check for any hash, malware, file, domain, IP URL, or malicious URL, and Kaspersky stays clean."
"I have never had any problems with stability or bugs while using VirusTotal."
"The product is easy to use with coding, such as Python or Java, via its API."
"It provides detailed insights into possible malicious behavior, dropped files, and TCP connections."
"It is quite simple for anyone if they just want to check some suspicious URLs."
 

Cons

"It is currently more suitable for end-users rather than enterprises with lots of other processes and third-party tools. It needs improvement on that front. We had many issues while integrating it with our enterprise solutions, such as Splunk, and third-party tools. It provides everything via APIs. Other vendors provide integration with third-party tools, but Microsoft doesn't do that. It is also logging too much and is not serialized from the process aspect. It has all the data, but it is not in a proper format or not properly indexed, which doesn't make it easier for enterprises to use this data. Other vendors provide troubleshooting information that can be used to troubleshoot issues, but Microsoft doesn't provide anything like that."
"Integrating this with third-party systems has some complexity involved."
"The alerting is something that needs to be improved. Alerts need to be sent immediately because as it is now, you see some of them without delay and others arrive perhaps 30 minutes later, and it leaves important gaps in terms of information gathering."
"The onboarding and deployment could be more user-friendly, and there is room to grow in some of the reports. I don't want them to be oversimplified or overly complex, but there is room for improvement in the reporting it can do. It's relatively minor."
"Microsoft Defender for Endpoint can have more options and more AI capabilities in the future, because everything keeps changing."
"I would like MDE to have the ability to isolate a certain amount of time on the timeline."
"Microsoft Windows Defender doesn't have a game mode."
"I'm not too sure of its current capabilities, but I'm pretty sure they are doing a good job on Windows and Mac. However, I'm not sure whether they covered Linux. If I remember correctly, Microsoft Defender didn't have anything proper on Linux back then, but if they have improved it from that aspect, it would already be ticking all the boxes."
"VirusTotal has predefined reports, but there is a lot of manual effort involved."
"VirusTotal is hard to understand because you need to know Google Docs to create queries, and it doesn't have documentation for that."
"There should be room for improvement, particularly in the API side of things."
"I would like to see improved correlation with other threat intelligence sources, not just reliant on its own database, to enhance the database of threat intelligence that VirusTotal offers."
"I would like to see improvements in the score consistency and accuracy."
"They can improve the telemetry. Whenever we handle a sample, they cannot provide any information about a victim."
"I would like to see an improved user interface and some automation."
"The platform could improve in the areas of endpoints and networks."
 

Pricing and Cost Advice

"This is an expensive product and licensing for all Microsoft products is a big issue."
"It's included with the Windows Operating System, I don't pay for any licensing fees."
"It is within the same range as other products. It is not too expensive, and it is also not cheap. Its price can be better, but, well, it is Microsoft."
"Microsoft Defender for Endpoint comes with Windows 10, and it's free. But for you to be able to manage it in the cloud and use the console, you need to have either an Office 365 E5 subscription or a Microsoft M365 subscription. You need to buy an extra license."
"I got it with the Microsoft Windows license."
"The subscription is part of Windows, so we don't have to pay anything extra for this product."
"It came with Windows."
"The solution is free with Windows."
"The pricing is reasonable."
"The pricing is very economical."
"We are using VirusTotal with free licenses, managing the license limits across three or four accounts, thus incurring no costs."
"VirusTotal is an expensive solution."
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Top Industries

By visitors reading reviews
Manufacturing Company
10%
Financial Services Firm
9%
Comms Service Provider
8%
Computer Software Company
8%
Comms Service Provider
12%
Computer Software Company
11%
Financial Services Firm
10%
Manufacturing Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise97
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise2
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What is your experience regarding pricing and costs for VirusTotal?
I do not know about the pricing or licensing as our organization services VirusTotal for our clients.
What needs improvement with VirusTotal?
I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the categ...
What is your primary use case for VirusTotal?
As I work in an incident response role, my daily task is to mitigate the security alert and perform the analysis part. When any alerts come, I check the IPs from where they originate and the locati...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Information Not Available
Find out what your peers are saying about Microsoft Defender for Endpoint vs. VirusTotal and other solutions. Updated: September 2026.
913,806 professionals have used our research since 2012.