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Microsoft Defender for Endpoint vs Uptycs comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Ranking in Endpoint Detection and Response (EDR)
5th
Average Rating
8.6
Reviews Sentiment
6.7
Number of Reviews
122
Ranking in other categories
Extended Detection and Response (XDR) (3rd), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
2nd
Ranking in Endpoint Detection and Response (EDR)
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Advanced Threat Protection (ATP) (6th), Anti-Malware Tools (1st), Microsoft Security Suite (3rd), Agentic Endpoint Security (3rd)
Uptycs
Ranking in Endpoint Protection Platform (EPP)
43rd
Ranking in Endpoint Detection and Response (EDR)
46th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Container Security (36th), Cloud Workload Protection Platforms (CWPP) (22nd), Extended Detection and Response (XDR) (43rd), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (22nd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of November 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, up from 3.6% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 6.4%, down from 9.5% compared to the previous year. The mindshare of Uptycs is 0.5%, up from 0.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.4%
Cortex XDR by Palo Alto Networks3.8%
Uptycs0.5%
Other89.3%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The information the dashboard provides is very clear."
"The product's most valuable features are massive user and feature intelligence exploit detection."
"Cortex covers everything I need. It's a perfect solution. Cortex provides a different level of visibility because it's an extended EDR, allowing you to grab logs from the network and firewalls. Palo Alto invented the concept of the extended EDR or XDR."
"It is a simple platform to use."
"Palo Alto is the core of the security infrastructure in the environment."
"The solution allows control over the user and his machine through Cortex XDR security policies."
"The user interface of the solution is sophisticated and straightforward."
"The initial setup is pretty easy."
"Microsoft Defender for Endpoint has been leading the field in EDR, and there are so many benefits to how that is managed versus the traditional products; that's huge."
"It is quite stable. We have not had any cases, i.e., viruses, that would require a reboot, etc. We have never had a situation where we needed to reinstall the tools as a result of the Defender application or a feature being corrupt."
"It works well with different solutions from Microsoft."
"Defender provides useful alerts and groups them. It sends an alert to your portal if it detects any malicious activity, and you can group multiple alerts to form an incident."
"Windows is a great tool that I have used; it has helped my organisation in achieving what it does daily and protected our data in a great way."
"The solution's latest features for threat analysis are updated to provide us with future protection against the latest threats worldwide."
"Web filtering is the most valuable feature of Microsoft Defender for Endpoint because it effectively maintains security for website access."
"The most valuable aspect lies in its automation capabilities, particularly within security automation."
"They have multiple great features."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
 

Cons

"The MAC agent is not as robust feature-wise as the PC version."
"I would like to see some additional features related to email protection included."
"However, if you do not have Palo Alto in your environment, you are paying these additional services just for Cortex XDR by Palo Alto Networks, so it is not a cost-effective solution."
"The server sometimes stops continuously to check things so it would be helpful to receive access updates or technical reasons."
"On the pricing aspect, Cortex XDR by Palo Alto Networks needs to have a more reasonable rate, particularly for customers in Sri Lanka and Asian countries."
"There are some limitations on the Traps agents."
"The tool needs to be improved in terms of integration and interface."
"Previously, the endpoint would leave the environment, not being on our VPN, essentially unable to interact with the server to upload files. It was unable to retrieve new file verdicts. It was using a thing called "local analysis" to determine if something was a malicious file or not. There was no dynamic analysis."
"In the next release, I would like to see better management reporting."
"We had some issues where phishing and malware were not detected and were allowed to pass unless I mentioned it or we forced the phishing or malware to be blocked, I can't rely on that alone."
"Sometimes it is a little lacking, but for the most part, they are able to provide exactly what I need."
"I would like to see the next generation of the tool improved to work with other operating systems, like Linux."
"Cortex... has good investigation capabilities, out-of-the-box, in case there is an event that you'd like to investigate. It's quite convenient. Microsoft has those capabilities as well, but you need a bit more training on the product to get the basic information that you can get out-of-the-box with Cortex."
"There are alternative solutions that offer a greater range of dashboard insights when compared to Microsoft Defender for Endpoint."
"Lacks some additional integration."
"The time it takes to implement policies has room for improvement."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
"We end up facing a lot of issues after upgrades."
 

Pricing and Cost Advice

"It's way too expensive, but security is expensive. You pay for your licensing, and then you pay for someone to monitor the stuff."
"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"Cortex XDR's pricing is ok."
"Traps pays for itself within the first 16 months of a three-year subscription. This is attributed to OPEX savings, as security teams spent less time trying to identify and isolate malware for analysis as a result of a reduction in malware incidents, false positives, and breach avoidance."
"The tool's price is moderate."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"The price of the solution is high for the license and in general."
"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"Currently, for us, Windows Defender is free with the purchase of Windows Server. Pricing is an important point for us when we are looking at the competitors of this solution. If we choose to go with another vendor, we will have to pay some license fees."
"For me, the pricing is very good, but for management it's very expensive. Other solutions are less expensive. But when I present all the information and all the reports they say, "Well, it's expensive, but the cost-benefit is very good.""
"The price is fair for the features Microsoft delivers. If you want tailor-made features, you have to mix different licenses. It isn't straightforward."
"When compared with other vendors, the pricing is very high."
"The product is free of charge and comes integrated into Windows."
"The solution is free."
"Microsoft Defender is an expensive product in my country."
"The license for Microsoft Defender for Endpoint is included in the license for the Microsoft Windows operating system."
Information not available
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Top Industries

By visitors reading reviews
Comms Service Provider
14%
Outsourcing Company
12%
Construction Company
10%
Manufacturing Company
10%
Manufacturing Company
10%
Financial Services Firm
9%
Comms Service Provider
8%
Outsourcing Company
8%
Comms Service Provider
14%
Computer Software Company
13%
Construction Company
11%
Financial Services Firm
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business50
Midsize Enterprise21
Large Enterprise57
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise97
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior sol...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never pu...
What is your experience regarding pricing and costs for Microsoft Defender for Endpoint?
We have been discussing pricing, setup cost, and licensing, and we are currently on an E3. We are discussing going to...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
No data available
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Petrofrac, Metro CSG, Christus Health
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Uptycs and other solutions. Updated: October 2026.
920,574 professionals have used our research since 2012.