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Microsoft Defender XDR vs Uptycs comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
5th
Ranking in Extended Detection and Response (XDR)
3rd
Average Rating
8.6
Reviews Sentiment
6.7
Number of Reviews
122
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Endpoint Detection and Response (EDR)
9th
Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Microsoft Security Suite (4th)
Uptycs
Ranking in Endpoint Detection and Response (EDR)
46th
Ranking in Extended Detection and Response (XDR)
43rd
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Endpoint Protection Platform (EPP) (43rd), Container Security (36th), Cloud Workload Protection Platforms (CWPP) (22nd), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (22nd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of November 2026, in the Endpoint Detection and Response (EDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, down from 3.8% compared to the previous year. The mindshare of Microsoft Defender XDR is 2.0%, down from 2.9% compared to the previous year. The mindshare of Uptycs is 0.7%, up from 0.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Detection and Response (EDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.8%
Microsoft Defender XDR2.0%
Uptycs0.7%
Other93.5%
Endpoint Detection and Response (EDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution doesn't need a high level of technical training."
"I don't have to do much monitoring with it; I don't have to have anybody manually looking at this, it gives us reports, and it lets us know if something needs to be addressed, and we can easily address it."
"It is an easy-to-use tool."
"The live terminal is probably the best thing ever. It gives you the access to get straight onto any machine."
"Threat identification and detection are the most valuable features of this solution."
"The solution allows control over the user and his machine through Cortex XDR security policies."
"Implementing Cortex XDR by Palo Alto Networks has had a significant impact on my security analyst workload because it becomes much easier."
"The ability to kind of stitch everything together and see the actual complete picture is very useful. I guess you'd call it a playbook. Some people call it the forensics analysis of what was happening on particular endpoints when they detected some malicious behavior, and what transpired before that to cause that. It is also very user friendly. The way they have done everything and integrated all the solutions that they've purchased over the years to make it a very seamless, effective product is very good. One thing about Palo Alto is that they take the products or services that they purchase and make them seamless for the end user as compared to some companies that purchase other companies and then just kind of have their products off to the side or keep different interfaces. Palo Alto doesn't do that."
"Its most significant advantage lies in its affordability."
"Microsoft Defender is stable."
"The unified view of the threat landscape on a central dashboard is the most valuable feature."
"The integration, visibility, vulnerability management, and device identification are valuable."
"The most valuable features are machine learning, AI, and auto-remediation of none malicious alerts."
"If you are considering Microsoft Defender XDR, my advice is that if you are looking for an XDR tool, Microsoft Defender XDR is the easiest to use."
"The support provides a 24 hrs service which I am completely satisfied with."
"Another noteworthy feature that I find appealing in Microsoft Defender is the credit-backed simulation. This feature enables organizations to train their users on effectively responding to phishing emails through a simulated training environment."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
"They have multiple great features."
 

Cons

"The connection to the internet has not performed as expected."
"They've been having some issues with updating their endpoint agents, and it has been quite frustrating."
"There are some default policies which sometimes affect our applications and cause them to run around."
"When it comes to core analysis, and security analysis, Cortex needs to provide more information."
"Impact on system performance is horrible, adding a lot of delays for users."
"It is an enterprise-level solution. Its price could be less expensive."
"It would be better if they could educate the customers more. Some sort of seminars and roadshows will help educate the customers and show what the product can do. The price could be better. It would also help if they had a team for deployment and support."
"Cortex XDR by Palo Alto Networks is a very good product, but financially, it is very expensive, so the company should look into that area."
"The console is missing some features that would be helpful for a managed services provider, like device and user management."
"Advanced attacks could use an improvement."
"The web filtering solution needs to be improved because currently, it is very simple."
"I'd like to see a wider solution that includes not only desktop devices but also other devices, such as servers, storage cabinets, switching equipment, et cetera."
"The licensing process needs improvement and clarification, as it is currently difficult to understand which features are licensed to which users."
"The documentation on their website is somewhat outdated and doesn't show properly. I wanted to try a query in Microsoft Defender 365. When I opened the related documentation from the security blog on the Microsoft website, the figures were not showing. It was difficult to understand the article without having the figures. The figures were there in the article, but they were not getting loaded, which made the article obsolete."
"The design of the user interface could use some work. Sometimes it's hard to find the exact information you need."
"The support team is not competent or responsive."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
"We end up facing a lot of issues after upgrades."
 

Pricing and Cost Advice

"Its pricing is kind of in line with its competitors and everybody else out there."
"It is "expensive" and flexible."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"The price of the product is not very economical."
"It is cost-effective compared to similar solutions. It fits for the small businesses through to the big businesses."
"The price is on the higher side, but it's okay."
"Cortex XDR by Palo Alto Networks is quite an expensive solution."
"I don't have any issues with the pricing. We are satisfied with the price."
"Microsoft Defender XDR is priced high."
"The pricing of Microsoft 365 Defender is definitely on the costly side, but with the features and services that Microsoft provides, such as the seamless integration of all the Defender tools, while the price is on the higher side, there is no alternative."
"It can be complex to navigate since customers have varying licensing agreements across Microsoft. If they go straightforward with E5 for all users, it's simple, but combinations based on budget constraints can complicate things."
"We've managed to navigate it effectively through our enterprise agreement, and Microsoft's academic discounts have proven to be quite generous."
"The bundling of software makes it easier to manage our setup, but Microsoft purposefully obfuscates this through marketing ploys to hide costs."
"The solution is affordable, and we haven't been hit with any hidden costs. The subscription model is straightforward, and it's easy to understand how much additional features cost. If we need to cancel a license or feature, we do that well in advance to avoid being charged for it, but overall, the pricing and licensing are simple and easy."
"The most valuable licensing option is expensive, so pricing could be improved. Licensing options for this solution also need to be consolidated, because they frequently change."
"Its licensing and pricing are handled by someone else. My role is limited to incidents or issues with the portal, but you get what you pay for. It is worth the cost."
Information not available
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Top Industries

By visitors reading reviews
Comms Service Provider
14%
Outsourcing Company
12%
Construction Company
10%
Manufacturing Company
10%
Financial Services Firm
8%
Outsourcing Company
8%
Comms Service Provider
8%
Computer Software Company
8%
Comms Service Provider
14%
Computer Software Company
13%
Construction Company
11%
Financial Services Firm
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business50
Midsize Enterprise21
Large Enterprise57
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

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Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender XDR vs. Uptycs and other solutions. Updated: September 2026.
920,574 professionals have used our research since 2012.