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Microsoft Defender XDR vs Uptycs comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
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Ranking in Endpoint Detection and Response (EDR)
5th
Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Endpoint Detection and Response (EDR)
9th
Ranking in Extended Detection and Response (XDR)
5th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Microsoft Security Suite (4th)
Uptycs
Ranking in Endpoint Detection and Response (EDR)
48th
Ranking in Extended Detection and Response (XDR)
40th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Endpoint Protection Platform (EPP) (44th), Container Security (36th), Cloud Workload Protection Platforms (CWPP) (23rd), Cloud Security Posture Management (CSPM) (32nd), Cloud-Native Application Protection Platforms (CNAPP) (23rd), Cloud Detection and Response (CDR) (12th)
 

Mindshare comparison

As of September 2026, in the Endpoint Detection and Response (EDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.6%, down from 3.9% compared to the previous year. The mindshare of Microsoft Defender XDR is 2.1%, down from 2.9% compared to the previous year. The mindshare of Uptycs is 0.6%, up from 0.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Detection and Response (EDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.6%
Microsoft Defender XDR2.1%
Uptycs0.6%
Other93.7%
Endpoint Detection and Response (EDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The tool's use cases are relevant to security."
"Automation and playbooks have helped me significantly, as Cortex Xnor's playbooks predefine the workflow of the automation, such as response processes, alert triggering, and enriching the context, efficiently detecting and blocking malicious attacks with firewalls while eliminating workload and speeding responses for next-generation operations."
"WildFire AI is the best option for this product."
"Cortex XDR by Palo Alto Networks's ability to block sophisticated threats in real time is quite good and is on par with SentinelOne's."
"It's a perfect solution. It integrates well into the environment."
"It is an easy-to-use tool."
"We think that this product will help us grow, as it meets our needs currently and we can grow with it over time."
"Cortex XDR alerts us on the dashboard when there's a threat, which allows us to restrict that user and helps secure our infrastructure."
"The support provides a 24 hrs service which I am completely satisfied with."
"The most valuable features of Microsoft 365 Defender are the combination of all the capabilities and centralized management."
"The incident-level visibility across the cyber attack chain when using Microsoft Defender XDR is great."
"I like that it's stable. It's been stable for a long time, and Microsoft Defender has done a good job there."
"Microsoft 365 Defender is a good solution and easy to use."
"Microsoft Defender XDR is scalable."
"Vulnerability assessment and just-in-time access are some valuable features of Defender for server plans."
"What I found most valuable in Microsoft 365 Defender is that it's able to scan emails and protect users from dangerous links or attachments."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
"They have multiple great features."
 

Cons

"Enhancing UI simplicity and playbook flexibility are areas that could benefit from more low-code automation options for smoother integrations."
"There are some third-party solutions that are difficult to integrate with, which is something that can be improved."
"There are some default policies which sometimes affect our applications and cause them to run around. In the hotel industry, we use a different type of data versus Oracle and SQL. By default, there are some policies which stop us from running properly. Because of this, the support level is also not that strong. We have to wait to get a results."
"Cortex XDR by Palo Alto Networks is not only pricey; it is extremely expensive."
"The downside to the solution is that there are a large number of false positives."
"There's room for improvement with Mac device installations, which can be challenging."
"In terms of areas of improvement, we have not completed our review of the product. We're also looking at other products. So, it's a little bit hard to tell what could be different because we have not completed the review of this product, but based on our experience so far, its implementation is quite complex."
"In reporting they should have a customizable dashboard due to the fact that C-level people don't like reporting to the IT department. They prefer to have a real-time dashboard. That kind of dashboard needs to have various customizations."
"Every now and then, Microsoft Defender XDR seems to go through and aggregates almost a week's worth of incidents and wraps them up, indicating a huge problem."
"What could be improved in Microsoft 365 Defender is its licensing; it needs to be more consolidated, because there are so many plans for Microsoft 365 Defender, and every other year, there will be new licensing options that become more and more different from each other."
"From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigger host isolation on one machine."
"The support could be more knowledgable to improve their offering."
"Their response time is okay, it works fine, but the time it takes to resolve escalated cases needs improvement."
"The solution can improve the rules and privileges it offers."
"Defender also lacks automated detection and response. You need to resolve issues manually. You can manage multiple Microsoft security products from a single portal, and all your security recommendations are in one place. It's easy to understand and manage. However, I wouldn't say Defender is a single pane of glass. You still need to switch between all of the available Microsoft tools. You can see all the alerts in one panel, but you can't automate remediation."
"There's still some more work to be done there. Additionally, the limited terminal live access an analyst has is very restricted."
"We end up facing a lot of issues after upgrades."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
 

Pricing and Cost Advice

"Our license will require renewal in August, after which the maintenance will continue as usual."
"Its pricing is kind of in line with its competitors and everybody else out there."
"The pricing is a little bit on the expensive side."
"The price of the product is not very economical."
"I don't like that they have different types of licenses."
"We pay about $50,000 USD per year for a bundle that includes Cortex XDR."
"The price of the solution could be reduced. I have customers that have voiced that the solution is good for the value but if I want to sell more of the solution the price reduction would help."
"The price was fine."
"While Microsoft Defender XDR carries a higher cost, its ease of use compared to Defender may justify the investment."
"I find the pricing to be quite competitive, especially considering its inclusion in our E5 subscription, which provides a comprehensive set of functionalities."
"The licensing fee for Microsoft 365 Defender is fair."
"The solution is affordable, and we haven't been hit with any hidden costs. The subscription model is straightforward, and it's easy to understand how much additional features cost. If we need to cancel a license or feature, we do that well in advance to avoid being charged for it, but overall, the pricing and licensing are simple and easy."
"The license cost for a year is approximately forty-four thousand, and this annual saving is a significant factor in our decision to switch."
"Microsoft is not competitive with the pricing of the solution. The competitors are able to offer lower discounts. The price of the solution is higher."
"Defender XDR is included in the E5 license, but it's a bit too expensive."
"365 Defender can get expensive because you pay per gigabyte of data ingested. On the other hand, much of the data available in the other Microsoft security solutions are made available relatively cheaply—sometimes at cost or for free. Integrating only a limited set of third-party solutions with Sentinel would be cost-effective. It's much more affordable if companies only have Microsoft stuff."
Information not available
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Financial Services Firm
9%
Financial Services Firm
9%
Computer Software Company
8%
Outsourcing Company
8%
Comms Service Provider
8%
Computer Software Company
14%
Financial Services Firm
12%
Construction Company
12%
Comms Service Provider
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
What needs improvement with Uptycs?
Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current...
What is your primary use case for Uptycs?
I use Uptycs as part of cloud security threat detection, vulnerability management, and security operations initiative...
What advice do you have for others considering Uptycs?
My advice for others looking into using Uptycs is that if you are looking for a centralized solution for all security...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender XDR vs. Uptycs and other solutions. Updated: September 2026.
913,683 professionals have used our research since 2012.