No more typing reviews! Try our Samantha, our new voice AI agent.

Microsoft Defender XDR vs Uptycs comparison

Sponsored
 

Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
6th
Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
112
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Endpoint Detection and Response (EDR)
8th
Ranking in Extended Detection and Response (XDR)
5th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Microsoft Security Suite (4th)
Uptycs
Ranking in Endpoint Detection and Response (EDR)
65th
Ranking in Extended Detection and Response (XDR)
45th
Average Rating
7.6
Reviews Sentiment
6.9
Number of Reviews
2
Ranking in other categories
Endpoint Protection Platform (EPP) (65th), Container Security (55th), Cloud Workload Protection Platforms (CWPP) (34th), Cloud Security Posture Management (CSPM) (45th), Cloud-Native Application Protection Platforms (CNAPP) (23rd), Cloud Detection and Response (CDR) (15th)
 

Mindshare comparison

As of June 2026, in the Endpoint Detection and Response (EDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.5%, down from 4.0% compared to the previous year. The mindshare of Microsoft Defender XDR is 2.5%, down from 2.8% compared to the previous year. The mindshare of Uptycs is 0.5%, up from 0.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Detection and Response (EDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.5%
Microsoft Defender XDR2.5%
Uptycs0.5%
Other93.5%
Endpoint Detection and Response (EDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
SangramGupta - PeerSpot reviewer
Security Consultant at Deloitte
Centralized visibility has improved risk-based vulnerability management but onboarding still needs simplification
From my perspective, the features of Uptycs that stand out more for my projects and organization are the vulnerability management, endpoint visibility, and asset inventory management features. I can share two specific outcomes that show this positive impact using Uptycs. First, it reduces significant time and effort from the asset inventory point of view because previously I needed to scan all of the assets which were in scope, but now I only scan those assets that are currently active and in scope, and the CMDB and asset inventory receive proper updates of those assets. Secondly, in vulnerability prioritization, I receive all the prioritized vulnerabilities so I can prioritize and mitigate or remediate them as soon as possible, which reduces the overall time of remediation as well.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"If you are looking for security, mainly for advanced threat prevention from ransomware and malware attacks, I would recommend Cortex."
"We can use Cortex XDR to get the entire graph of the incidents from source to destination, and we can take remedial action."
"Cortex XDR by Palo Alto Networks should be a stable solution."
"From the Palo Alto side, whatever they buy, they integrate that really well into their integration suite, and that makes a massive difference."
"The one feature of Palo Alto Networks Traps that our organization finds most valuable is the App ID service."
"The positive impacts I see from Cortex XDR by Palo Alto Networks include a complete 360-degree view of our security posture altogether, being a uniform platform where we are ingesting logs from multiple resources."
"Stability is one of the features we like the most."
"Stability is a primary factor, and then there's the ease of distribution and policy management; Cortex XDR by Palo Alto Networks is very easy to work with, and we're quite happy with them."
"The 'Incidents and Alerts' tab is a valuable feature where we can find triggered alerts."
"The common and advanced security policies for threat hunting and blocking attacks are valuable."
"Microsoft 365 Defender is a stable solution."
"From an attack chain perspective, Defender XDR handles phishing and spam emails easily, while Defender for Endpoint manages endpoints effectively. We've drastically improved our user experience."
"Many people don't realize that Microsoft Azure, Exchange Online, and the security and compliance portal all sync together. For instance, within the Azure portal you can set security restrictions and policies to help secure your tenants... The good part of it is that these products have already been integrated. When you sign on as an admin you have global admin rights and that gives you access to all these features."
"The most valuable feature of all is the full integration with the rest of the software in the operating system and Office 365, as well as Microsoft SCCM. It is quite easy for us to work with the whole instance of Microsoft products. This integration improves the benefits of the whole suite of products."
"I like that Defender is easy to use and the alerts are all in one central location."
"I have found the ability to delete unwanted threats beneficial."
"They have multiple great features."
"I have seen a return on investment from using Uptycs, saving almost 25 to 30 percent in terms of asset investigations or asset inventory management and vulnerability prioritization, which is significant."
 

Cons

"In the next release, I would like to see more UI improvements. Their UI is a bit basic. When we are speaking about Palo Alto Networks they are the big company, so they can improve the UI a little bit. The UI, the reports, the log system can all be improved."
"There is also no recovery feature; if some endpoint is under attack there must be the possibility of recovering it or restoring it to a normal state."
"Cortex XDR by Palo Alto Networks could improve by offering remote management. It would be useful to look at the client's issue to fix it."
"Palo Alto Networks Cortex XDR does not detect malicious activity like in other anti-virus solutions like Trend Micro and Windows with Cisco."
"As an improvement, I would like to see enhanced connection speeds."
"I don't like that they have different types of licenses. For example, if users select a license, they think they will have all the platforms they need to improve their network or security. But after some time, Palo Alto Networks changed their licensing, and some of the features that, for example, were free at the beginning now have a cost. I think the integration can be improved. For example, a lot of tools are just integrated through APIs."
"Impact on system performance is horrible, adding a lot of delays for users."
"The technical support is not very good. I find the process difficult."
"Improving scalability, especially for very large tenants, could be beneficial for Microsoft Defender XDR."
"The price should be adjustable by region."
"It would be highly beneficial if CoPilot could identify anomalies within the network and notify the IT team."
"Defender also lacks automated detection and response. You need to resolve issues manually. You can manage multiple Microsoft security products from a single portal, and all your security recommendations are in one place. It's easy to understand and manage. However, I wouldn't say Defender is a single pane of glass. You still need to switch between all of the available Microsoft tools. You can see all the alerts in one panel, but you can't automate remediation."
"There could be a way to proactively monitor unusual activity ."
"The tool gives inconsistent answers and crashes a lot."
"There should be better information for experts on features in the solution. What I see when reading about features in Microsoft 365 Defender is that it is always general information. If Microsoft could go deeper into details for the experts about how to use the tools, usage of it would be more familiar and it would be easier to use."
"The console is missing some features that would be helpful for a managed services provider, like device and user management."
"Regarding improvements for Uptycs, I suggest simplified onboarding for complex cloud environments because the current onboarding method is complex and requires checks with the support team."
"We end up facing a lot of issues after upgrades."
 

Pricing and Cost Advice

"This is an expensive solution."
"I am using the Community edition."
"I don't have any issues with the pricing. We are satisfied with the price."
"It has a higher cost than other solutions, like CrowdStrike or Microsoft’s EDR tools, but it reduces the cost of our operations because it’s a new generation antivirus tool."
"When we first bought it, it was a bit expensive, but it was worth it. The licensing was straightforward."
"We pay about $50,000 USD per year for a bundle that includes Cortex XDR."
"Our customers have expressed that the price is high."
"Licensing for Palo Alto Networks Cortex XDR can be costly, especially when it comes to a hundred users. A license is required for each user, and the subscription must be renewed on a yearly basis."
"There are no issues with pricing, but sometimes, the clarity in licensing is a concern."
"With the little idea I have about the costs, I can say that XDR tools tend to be a bit expensive. If you are using Microsoft Defender XDR, then you need to go for a subscription-based pricing model."
"We have a lot of problems in Latin America regarding the price of Microsoft 365 Defender, because the relationship between dollars and the money of the different countries, it's is a lot. Many customers that have small businesses say that they would like the solution but it is too expensive. However, large companies do not find the cost an issue."
"We've managed to navigate it effectively through our enterprise agreement, and Microsoft's academic discounts have proven to be quite generous."
"It is 15 dollars per server per month. It is worth it, but it can be costly. It depends on the company's size."
"The pricing of Microsoft 365 Defender is definitely on the costly side, but with the features and services that Microsoft provides, such as the seamless integration of all the Defender tools, while the price is on the higher side, there is no alternative."
"365 Defender is billed per account. I don't know the exact price, but my supervisor told me that Microsoft Defender is cheaper than the alternatives. It's bundled, so you get all the features in one place."
"I would like to have more security features in the lower licenses because not every customer is able to buy E5 licenses. The bundling isn't always easy for our customers to understand. Compared to other tools, it's a good price."
Information not available
report
Use our free recommendation engine to learn which Endpoint Detection and Response (EDR) solutions are best for your needs.
900,644 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
10%
Comms Service Provider
9%
Computer Software Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Manufacturing Company
7%
Financial Services Firm
20%
Construction Company
13%
Computer Software Company
6%
Insurance Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise20
Large Enterprise52
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
Ask a question
Earn 20 points
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Comcast, Crossbeam, Flexport, Greenlight Financial, Lookout Security, PayNearMe
Find out what your peers are saying about Microsoft Defender XDR vs. Uptycs and other solutions. Updated: June 2026.
900,644 professionals have used our research since 2012.