In my opinion, all gateways including Mimecast or Defender for O365 or ProofPoint work hand-in-hand in their respective mechanics and algorithms built. And definitely has its own advantages. However, I have been using it for my customers' MDO which is far better. I would say relying on gateways is important but at the same time USER education and reporting back to the IT administrator far important as well.
Senior IT Security Specialist at a tech services company with 1,001-5,000 employees
Real User
Apr 25, 2023
Greetings Matingou, Defender for O365 I would say would suffice as it has all the tools included in Mimecast in just one single tool, may take some time to navigate at first as it gives a lot of information in just one tool but once you know your way around, you will be able to have good visibility on your email threats landscape by provides a range of protections against email-based threats such as spam, phishing, malware, and etc. It also includes features such as URL protection and attachment scanning to prevent users from clicking on malicious links or downloading harmful files. but on the other hand, Mimecast might be needed, if you require compliance measures, including data loss prevention, archiving, and encryption. It also provides greater visibility and control over email security, allowing you to monitor and manage threats in real-time. Hope this helps.
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Mimecast Email and Collaboration Threat Protection and other solutions. Updated: February 2026.
Mimecast Advanced Email Security and Microsoft Defender for Office 365 compete in the email security market. Users generally favor Microsoft Defender for its integration with Office 365 and cost-effectiveness.
Features: Mimecast is praised for its sandboxing, archiving, and advanced threat protection capabilities, handling suspicious emails and attachments effectively. Microsoft Defender for Office 365 offers anti-phishing, Safe Links, and Safe Attachments with strong integration across...
In my opinion, all gateways including Mimecast or Defender for O365 or ProofPoint work hand-in-hand in their respective mechanics and algorithms built. And definitely has its own advantages. However, I have been using it for my customers' MDO which is far better. I would say relying on gateways is important but at the same time USER education and reporting back to the IT administrator far important as well.
Greetings Matingou, Defender for O365 I would say would suffice as it has all the tools included in Mimecast in just one single tool, may take some time to navigate at first as it gives a lot of information in just one tool but once you know your way around, you will be able to have good visibility on your email threats landscape by provides a range of protections against email-based threats such as spam, phishing, malware, and etc. It also includes features such as URL protection and attachment scanning to prevent users from clicking on malicious links or downloading harmful files. but on the other hand, Mimecast might be needed, if you require compliance measures, including data loss prevention, archiving, and encryption. It also provides greater visibility and control over email security, allowing you to monitor and manage threats in real-time. Hope this helps.