Senior Cybersecurity Engineer at a financial services firm with 11-50 employees
Real User
Top 5
Jul 29, 2025
The main use case for Cisco Secure Email Threat Defense is as a gateway for email traffic into and out of the organization. It serves as the primary conduit for emails, providing content filtering, compliance-based email filtering, and DLP features. Users can manage their own email, especially for interactions with clients and vendors, reducing reliance on help desk support.
I use Cisco Secure Email Threat Defense as a customer. I can explain that I'm using Cisco Secure Email Threat Defense for advanced email threats, such as business email compromise and phishing attacks. The solution also handles clawback functionality.
Learn what your peers think about Cisco Secure Email Threat Defense. Get advice and tips from experienced pros sharing their opinions. Updated: May 2026.
IT Professional at a construction company with 1,001-5,000 employees
Real User
Top 20
Aug 4, 2022
You need to have email security on your entry point. It helps us to avoid all the spam mails and getting your domain blacklisted, et cetera. In the initial stages, the security solution provided by Microsoft was not strong enough or not mature enough. So we had this in place and were able to see if mail received on the domain is spam mail or not. If there is malware within an attachment, it goes for analysis and is sandboxed, and sends back the attachment once it is cleared.
Product Manager-Cyber Security & Networking Active at a tech services company with 501-1,000 employees
Reseller
Dec 14, 2021
I am a solution provider. When it comes to email security, the main threat factor today is email. So we follow the rule of thumb that any and all customer emails must be malware-free. That is how we intend to approach it.
Systems Administrator at a university with 10,001+ employees
Real User
Jun 28, 2020
We're using it to collect data. We haven't fully implemented any of the features to stop any attacks. At this point we're using it for informational purposes, until we get a better grasp on everything. It's gathering any spam messages or malicious email messages that come through. It's in the cloud and hosted by Cisco.
Our primary use case is the ability to see email activity in the east-west traffic. It does internal email tracking as well as leveraging it as another layer of email defense. We utilize Microsoft 365 (enterprise service) and its Advanced Threat Protection solution, which networks inline with Cisco Secure Email Cloud Mailbox. Then, Cisco Secure Email Cloud Mailbox does an additional layer of detection and protection against malicious email. Business email compromise is the internal user use case, then phishing and malware delivery are certainly others. They are pretty common and definitely answered by Cisco Secure Email Cloud Mailbox. After several months of use, Cisco Secure Email Cloud Mailbox has provided additional capabilities (and value) which enables much faster mal-email remediation times.
Cisco Secure Email Threat Defense offers robust email security with features like east-west traffic visibility and seamless SaaS deployment. It enhances cloud email protection by integrating Threat Grid sandboxing and AMP for malware defense, supported by Cisco Talos threat intelligence.Enhancing email security for Microsoft 365 and cloud emails, Cisco Secure Email Threat Defense acts as an email gateway, blocking phishing, malware, and business email compromise. Users benefit from a...
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
The main use case for Cisco Secure Email Threat Defense is as a gateway for email traffic into and out of the organization. It serves as the primary conduit for emails, providing content filtering, compliance-based email filtering, and DLP features. Users can manage their own email, especially for interactions with clients and vendors, reducing reliance on help desk support.
I use Cisco Secure Email Threat Defense as a customer. I can explain that I'm using Cisco Secure Email Threat Defense for advanced email threats, such as business email compromise and phishing attacks. The solution also handles clawback functionality.
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger.
We use the solution for email security.
We use the solution for email security. We used cloud ESA and Microsoft Office 365 for email filtering, especially for spam.
We are using the solution as a secure mailbox. We do provide this solution to customers. The main use case is for email protection.
You need to have email security on your entry point. It helps us to avoid all the spam mails and getting your domain blacklisted, et cetera. In the initial stages, the security solution provided by Microsoft was not strong enough or not mature enough. So we had this in place and were able to see if mail received on the domain is spam mail or not. If there is malware within an attachment, it goes for analysis and is sandboxed, and sends back the attachment once it is cleared.
I am a solution provider. When it comes to email security, the main threat factor today is email. So we follow the rule of thumb that any and all customer emails must be malware-free. That is how we intend to approach it.
My primary use case is to protect cloud-based emails.
It can be deployed either on-premise or in the cloud. We have two options if it is in the cloud, a private cloud or a public cloud.
We're using it to collect data. We haven't fully implemented any of the features to stop any attacks. At this point we're using it for informational purposes, until we get a better grasp on everything. It's gathering any spam messages or malicious email messages that come through. It's in the cloud and hosted by Cisco.
Our primary use case is the ability to see email activity in the east-west traffic. It does internal email tracking as well as leveraging it as another layer of email defense. We utilize Microsoft 365 (enterprise service) and its Advanced Threat Protection solution, which networks inline with Cisco Secure Email Cloud Mailbox. Then, Cisco Secure Email Cloud Mailbox does an additional layer of detection and protection against malicious email. Business email compromise is the internal user use case, then phishing and malware delivery are certainly others. They are pretty common and definitely answered by Cisco Secure Email Cloud Mailbox. After several months of use, Cisco Secure Email Cloud Mailbox has provided additional capabilities (and value) which enables much faster mal-email remediation times.