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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
5th
Average Rating
8.6
Reviews Sentiment
6.7
Number of Reviews
120
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (3rd), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
26th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (26th), Cisco Security Portfolio (7th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
69th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of October 2026, in the Endpoint Detection and Response (EDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.7%, down from 3.9% compared to the previous year. The mindshare of Cisco Secure Endpoint is 1.3%, down from 1.6% compared to the previous year. The mindshare of MetaDefender Endpoint is 0.4%, up from 0.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Detection and Response (EDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks3.7%
Cisco Secure Endpoint1.3%
MetaDefender Endpoint0.4%
Other94.6%
Endpoint Detection and Response (EDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The tool's use cases are relevant to security."
"My advice for anybody who is considering Cortex XDR is that it is a complete solution, and has very good features."
"The most valuable features of this product are the management capabilities, which allow an IT organization to get quite a good picture of attempted cyber attacks, and its out-of-the-box investigation capabilities."
"We've had a significant increase in blocking with a decrease in false positives, because it's looking at how the files work, not just a list of files that it's been told to look for."
"WildFire AI is the best option for this product."
"The level of security I get for my endpoints and servers is extremely valuable."
"Cortex XDR can integrate the firewalls and determine the tendencies of the attacks. It's a new generation antivirus, with protection endpoints and detection response. It is very easy to use and everybody can operate the solution."
"Since using Cortex XDR by Palo Alto Networks, our MTTR has reduced, which means the mean time to resolve any ticket has been reduced."
"[It has helped our organization] tremendously. First of all, because we are always on-point in terms of our solution. We are proactively looking into the alerts and Cisco Secure Endpoint is already taking care of looking into it, provisioning it, and fixing it."
"With Cisco Secure Endpoint, we now have visibility over what is happening on the endpoint side."
"The most valuable feature of the solution is its technical support."
"Integration is a key selling factor for Cisco security products. We have a Cisco Enterprise Agreement with access to Cisco Email Security, Cisco Firepower, Cisco Stealthwatch, Cisco Talos, Cisco Threat Grid, Cisco Umbrella, and also third-party solutions. This is key to our security and maximizing operations. Because we do have the Email Security appliance and it is integrated with Threat Response, we have everything tied together. Additionally, we are using the Cisco SecureX platform, as we were a beta test for that new solution. With SecureX, we are able to pull all those applications into one pane for visibility and maintenance. This greatly maximizes our security operations."
"The solution is easy to deploy and applies multi-factor authentication."
"The most valuable features of this solution are the IPS and the integration with ISE."
"The solution makes it possible to see a threat once and block it everywhere across all endpoints and the entire security platform. It has the ability to block right down to the file and application level across all devices based on policies, such as, blacklisting and whitelisting of software and applications. This is good. Its strength is the ability to identify threats very quickly, then lock them and the network down and block the threats across the organization and all devices, which is what you want. You don't want to be spending time working out how to block something. You want to block something very quickly, letting that flow through to all the devices and avoiding the same scenario on different operating systems."
"We are estimating 5 to 10 percent staff productivity increases."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"They are charging for Network Traffic Analyzer (NTA) services, so if the per GB data could be provided at a certain level free of cost or at the same cost which the customer is taking for the entire bundle, that would be better."
"A potential area of improvement for Cortex XDR by Palo Alto Networks is the cost."
"One thing that was missing was the integration part. Currently, they don't have out-of-box integration with IBM QRadar, or if they have the integration, the integration doesn't work well."
"It would be better if they could educate the customers more. Some sort of seminars and roadshows will help educate the customers and show what the product can do. The price could be better. It would also help if they had a team for deployment and support."
"Currently, we are monitoring all USB drives and ports but we would like to improve our device control capabilities."
"However, if you do not have Palo Alto in your environment, you are paying these additional services just for Cortex XDR by Palo Alto Networks, so it is not a cost-effective solution."
"Whenever the tool releases a new version when deploying the product across the organization, I feel like there are some disturbances in the CPU usage after upgrading the tool to the latest version."
"Impact on system performance is horrible, adding a lot of delays for users."
"The thing I hate the most, which they have not fixed, is when it creates duplicate entries within a console. If you have a computer and you upgrade from Windows 7 to Windows 10, or you upgrade your agent from version 6 to 7, it creates a new instance in there instead of updating the information. Instead of paying a license for one computer, I have to license two computers until I manually go in, search for all the duplicate entries, and clean them out myself."
"The room for improvement would be on event notifications. I have mine tuned fairly well. I do feel that if you subscribe to all the event notification types out-of-the-box, or don't really go through and take the time to filter out events, the notifications can become overwhelming with information. Sometimes, when you're overwhelmed with information, you just say, "I'm not going to look at anything because I'm receiving so much." I recommend the vendor come up with a white paper on the best practices for event notifications."
"The technical support is very slow."
"Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with third-party tools need improvement."
"Cisco is good in terms of threat intelligence plus machine learning-based solutions, but we feel Cisco is lagging behind in using artificial intelligence in its systems."
"We would like to have an API integration with a SIEM solution, because as far as I know, it currently hasn't yet been released."
"The integration of the Cisco products for security could be better in the sense that not everything is integrated, and they aren't working together. In addition, not all products are multi-tenant, so you can't separate different customer environments from each other, which makes it a little bit hard for a managed service provider to deliver services to the customers."
"The solution needs more in-depth analytics."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"The pricing is a little high. It is per user per year."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"We pay about $50,000 USD per year for a bundle that includes Cortex XDR."
"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"I feel it is fairly priced."
"I don't recall what the cost was, but it wasn't really that expensive."
"In terms of the cost Cortex XDR by Palo Alto Networks is very expensive because we are a Mexican company and when you translate dollars to pesos the cost is very high. The solution is very expensive for Mexican companies. I understand that they have international prices, but I do not think it offsets the price enough for many companies in countries, such as Mexico. The amount it is reduced is not a massive percentage."
"I don't like that they have different types of licenses."
"Cisco Secure Endpoint is not too expensive and it's not cheap. It's quite fair."
"The price is very good."
"The price is very fair to the customer."
"It is quite cost-effective. I would rate it ten out of ten."
"The pricing and licensing of the security solutions of Cisco are very good in comparison with the competitors, but sometimes, it's difficult to see all the discounts and other kinds of things. So, you have to be careful, but the pricing is good."
"The solution's price is about the same as that of Palo Alto solutions."
"There is also the Cisco annual subscription plus my management time in terms of what I do with the Cisco product. I spend a minimal amount of time on it though, just rolling out updates as they need them and monitoring the console a couple of times a day to ensure nothing is out of control. Cost-wise, we are quite happy with it."
"We can know if something bad is potentially happening instantaneously and prevent it from happening. We can go to a device and isolate it before it infects other devices. In our environment, that's millions of dollars saved in a matter of seconds."
Information not available
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Top Industries

By visitors reading reviews
Comms Service Provider
13%
Outsourcing Company
12%
Construction Company
11%
Manufacturing Company
10%
Manufacturing Company
12%
Financial Services Firm
9%
Outsourcing Company
8%
Construction Company
8%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business48
Midsize Enterprise21
Large Enterprise56
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise15
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What is your primary use case for Cisco Secure Endpoint?
We deployed Cisco Secure Endpoint for our customers two to three years back. The use case was to secure their endpoin...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
Find out what your peers are saying about CrowdStrike, SentinelOne, Microsoft and others in Endpoint Detection and Response (EDR). Updated: October 2026.
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