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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
6th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
110
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (5th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
26th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (32nd), Cisco Security Portfolio (8th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
70th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The product is very good, it has caught a lot of exploits that most products would not."
"Cortex is the best tool for endpoint detection, and I have used it to verify hashes or domains to identify malicious activity, trigger playbooks that automate and gather endpoint logs, block malicious processes, and update incident tickets, showcasing end-to-end processes with automation in investigation and reducing the analysis workflow."
"Cortex XDR is a very capable solution for protecting large networks and a lot of endpoints. It's very useful because the automation is very high, and if you combine it with the features on Palo Alto firewalls, it provides very strong protection."
"When the pandemic started, Palo Alto came up with many solutions, which helped with the quick shift from on-premises to the cloud."
"Cortex is the best solution for avoiding security breaches, malware attacks, and other kinds of security issues."
"The normal protection was really effective, and we detected situations that if we didn't have Cortex XDR by Palo Alto Networks, it's highly likely that we would have been affected, but it protected the infrastructure."
"They did what they said. This solution could apply to any scenario."
"WildFire AI is the best option for this product."
"The ability to detonate a particular problem in a sandbox environment and understand what the effects are, is helpful. We're trying, for example, to determine, when people send information in, if an attachment is legitimate or not. You just have to open it. If you can do that in a secure sandbox environment, that's an invaluable feature. What you would do otherwise would be very risky and tedious."
"We have seen a measurable decrease in the mean time to detect or respond to threats by 90 percent, blocking a vast majority of threats."
"With Cisco Secure Endpoint, we now have visibility over what is happening on the endpoint side."
"The most valuable feature is its threat protection and data privacy, including its cyber attack and data protection, as we need to cover and protect data on user devices."
"The product provides sandboxing options like file reputation and file analysis."
"There are no issues or drops in the solution's performance...The solution's technical support was helpful."
"The implementation was performed, with support from Cisco partners, in a few hours and in the following days AMP 4 Endpoints found many things that the old antivirus solution missed, which was a very huge advantage for us."
"AMP and the rest of the security stack from Cisco give me peace of mind that the network is taking care of itself and that the endpoints are protected."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth."
"The product's pricing needs improvement. They could provide more discounts. Additionally, the dashboard and control panel could be enhanced."
"There are some third-party solutions that are difficult to integrate with, which is something that can be improved."
"The connection to the internet has not performed as expected."
"I feel that it should not be a licensed activity because a feature should allow us to see applications running on end devices."
"The dashboard could use some significant improvement, just making it more useful with more information. It has a limited amount of information right now. It is customizable, but I'd love to see a better out-of-box dashboard."
"Previously, the endpoint would leave the environment, not being on our VPN, essentially unable to interact with the server to upload files. It was unable to retrieve new file verdicts. It was using a thing called "local analysis" to determine if something was a malicious file or not. There was no dynamic analysis."
"This product has not improved my organization - in fact, we are in the process of moving back to another product as a result of Cortex's horrible impact on system performance."
"We would like to have an API integration with a SIEM solution, because as far as I know, it currently hasn't yet been released."
"We don't have issues. We think that Cisco covers all of the security aspects on the market. They continue to innovate in the right way."
"Logging could be better in terms of sending more logs to Cisco Firepower or Cisco ASA. That's an area where it could be made better."
"I would like them to add whatever makes filtering more advanced in scanning and blocking for malware in emails."
"The room for improvement would be on event notifications. I have mine tuned fairly well. I do feel that if you subscribe to all the event notification types out-of-the-box, or don't really go through and take the time to filter out events, the notifications can become overwhelming with information. Sometimes, when you're overwhelmed with information, you just say, "I'm not going to look at anything because I'm receiving so much." I recommend the vendor come up with a white paper on the best practices for event notifications."
"One of the things that Cisco Secure Endpoint really needs is that it's not just Secure Endpoint, it's a point product, and I think we really need to move into solution-based selling, designing, and architecting. So that we're not worried about putting things on endpoints and selling 'x' amount of endpoints, but to provide a solution that covers all of the remote access and sell them as solutions that cover multiple things."
"I would like to see integration with Cisco Analytics."
"The thing I hate the most, which they have not fixed, is when it creates duplicate entries within a console."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"We didn't have to pay any additional fee for the cloud instance. It just came with the renewal, which was nice."
"It has reasonable pricing for the use cases it provides to the company."
"I don't have any issues with the pricing. We are satisfied with the price."
"The return on investment is from the user side because we have seen the performance of it increase the delivery time of the product if we are using too many web-based and on-premise applications. In indirect ways, we saw the return of investment in terms of performance and user satisfaction increase."
"This is an expensive solution."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"It's way too expensive, but security is expensive. You pay for your licensing, and then you pay for someone to monitor the stuff."
"When we first bought it, it was a bit expensive, but it was worth it. The licensing was straightforward."
"The Enterprise Agreement is like an all-you-can-eat buffet of Cisco products. In that vein, it was very affordable."
"It is quite cost-effective. I would rate it ten out of ten."
"In our case, it is a straightforward annual payment through our Enterprise Agreement."
"Pricing is a big issue."
"Licensing fees are on a yearly basis and I am happy with the pricing."
"Our company was very happy with the price of Cisco AMP. It was about a third of what we were paying for System Center Endpoint Protection."
"The pricing and licensing are reasonable. The cost of AMP for Endpoints is inline with all the other software that has a monthly endpoint cost. It might be a little bit higher than other antivirus type products, but we're only talking about a dollar a month per user. I don't see that cost as being an issue if it's going to give us the confidence and security that we're looking for. We have had a lot of success and happiness with what we're using, so there's no point in changing."
"My company does make annual payments towards the licensing costs of the solution. Cisco Secure Endpoint is a little bit expensive."
Information not available
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Top Industries

By visitors reading reviews
Financial Services Firm
12%
Construction Company
12%
Comms Service Provider
9%
Manufacturing Company
8%
Manufacturing Company
10%
Comms Service Provider
8%
Government
8%
Financial Services Firm
7%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business45
Midsize Enterprise21
Large Enterprise48
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise14
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What do you like most about Cisco Secure Endpoint?
The product's initial setup phase was very simple.
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
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