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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
7th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
108
Ranking in other categories
Endpoint Protection Platform (EPP) (5th), Extended Detection and Response (XDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (2nd)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
25th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (34th), Cisco Security Portfolio (7th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
75th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It can automatically correlate events and logs, which is very helpful for an IT administrator. It can correlate different kinds of malware activities over a network, agent, or host system. You do not need to do it manually. It is a good feature. It is also a user-friendly solution. We have deployed it on the cloud because our space does not provide any flexibility for on-premises deployment, but Palo Alto has added some flexibility to install it on-premises. It must be like the same Cortex XDR agent for all the VPN services, web filtering services, and everything else."
"The stability of this product is very good."
"WildFire AI is the best option for this product."
"They did what they said. This solution could apply to any scenario."
"We have a complete overview of all our PCs and it's very easy to handle and to use the interface. It has a lot of benefits for us."
"The solution helps find bugs, and it is safe to use to prevent attacks by hackers."
"The management capabilities, allow an IT organization to get quite a good picture of attempted cyber attacks."
"Cortex XDR by Palo Alto Networks is easy to use and does not consume a lot of hardware resources."
"It provides real-time visibility and control over endpoints, allowing its users to promptly respond to any security incidents and remediate any vulnerabilities."
"It is a very stable program."
"For the initial first level of support, we provide it from our side. If there's escalation required, we use Cisco tech for the AMP. And again, they are perfect. I mean, one of the best, compared to any other vendors."
"The solution's integration capabilities are excellent. It's one of the best features."
"Another of my favorite features is called the Device Trajectory, where it shows everything that's going on, on a computer. It shows the point in time when a virus is downloaded, so you can see if the user was surfing the internet or had a program open. It shows every running process and file access on the computer and saves it like a snapshot when it detects something malicious. It also has a File Trajectory, so you can even see if that file has been found on any of your other computers that have AMP."
"The product provides sandboxing options like file reputation and file analysis."
"Its most valuable features are its scalability and advanced threat protection for customers."
"The VPN is most valuable. It's the best thing in the market today. We can use two-factor authentication with another platform, and we can authenticate with two-factor."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"Product might have some bugs."
"We have found that there are times Cortex XDR by Palo Alto Networks does not detect some of the viruses, we have to use another protection solution called Kaspersky."
"It is not easy to sell Cortex XDR, not because it isn't a good tool. Its marketing needs to be improved."
"I recommend adding a data loss prevention (DLP) solution to Cortex XDR by Palo Alto Networks. The inclusion of this feature would allow the application of DLP policies alongside antivirus policies via a single agent and console, making it more competitive as other OEMs often offer DLP solutions as part of their antivirus products."
"There are a large number of false positives."
"A little bit more automation would be nice."
"Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth."
"Enhancing UI simplicity and playbook flexibility are areas that could benefit from more low-code automation options for smoother integrations."
"I would like more seamless integration."
"We would like to have an API integration with a SIEM solution, because as far as I know, it currently hasn't yet been released."
"The integration of the Cisco products for security could be better in the sense that not everything is integrated, and they aren't working together. In addition, not all products are multi-tenant, so you can't separate different customer environments from each other, which makes it a little bit hard for a managed service provider to deliver services to the customers."
"Due to the complexity of the technology that is used and its advanced threat detection capabilities, it is possible to encounter many delays in operation."
"In the next release, I would for it to have back up abilities. I would like the ability to go back to a point in time to when my PC was uninfected and to the moment of when the infection happened."
"The thing I hate the most, which they have not fixed, is when it creates duplicate entries within a console. If you have a computer and you upgrade from Windows 7 to Windows 10, or you upgrade your agent from version 6 to 7, it creates a new instance in there instead of updating the information. Instead of paying a license for one computer, I have to license two computers until I manually go in, search for all the duplicate entries, and clean them out myself."
"Maybe there is room for improvement in some of the automated remediation. We have other tools in place that AMP feeds into that allow for that to happen, so I look at it as one seamless solution. But if you're buying AMP all by itself, I don't know if it can remove malicious software after the fact or if it requires the other tools that we use to do some of that."
"Logging could be better in terms of sending more logs to Cisco Firepower or Cisco ASA. That's an area where it could be made better."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"It is present, but when compared to other competitive products, I would say it is not less expensive; however, when all of the other added values are considered, the price is reasonable."
"In terms of the cost Cortex XDR by Palo Alto Networks is very expensive because we are a Mexican company and when you translate dollars to pesos the cost is very high. The solution is very expensive for Mexican companies. I understand that they have international prices, but I do not think it offsets the price enough for many companies in countries, such as Mexico. The amount it is reduced is not a massive percentage."
"It has a higher cost than other solutions, like CrowdStrike or Microsoft’s EDR tools, but it reduces the cost of our operations because it’s a new generation antivirus tool."
"Cortex XDR's pricing is ok."
"We pay about $50,000 USD per year for a bundle that includes Cortex XDR."
"It's the most expensive solution, but features-wise, it's quite strong. It's very good for protection, so the results are very good in the case of protection. I would rate it a two out of ten in terms of pricing."
"Licensing for Palo Alto Networks Cortex XDR can be costly, especially when it comes to a hundred users. A license is required for each user, and the subscription must be renewed on a yearly basis."
"It has a yearly renewal."
"The price is very fair to the customer."
"There are a couple of different consumption models: Pay up front, or if you have an enterprise agreement, you can do a monthly thing. Check your licensing possibilities and see what's best for your organization."
"Its price is fair for us."
"The solution's price is about the same as that of Palo Alto solutions."
"The Enterprise Agreement is like an all-you-can-eat buffet of Cisco products. In that vein, it was very affordable."
"The solution is highly affordable; I believe we pay $2 or $3 per endpoint. It's significantly cheaper than the competitors on the market."
"We had faced some license issues, but it has been improved. At the beginning of the implementation, we faced a lot of licensing issues, but now, we have EA licensing, which gives us an opportunity to grow."
"The costs of 50 licenses of AMP for three years is around $9,360."
Information not available
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Top Industries

By visitors reading reviews
Computer Software Company
9%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Manufacturing Company
10%
Computer Software Company
10%
Government
8%
Healthcare Company
7%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business44
Midsize Enterprise20
Large Enterprise47
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise14
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What do you like most about Cisco Secure Endpoint?
The product's initial setup phase was very simple.
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
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