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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
6th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
112
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
26th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (29th), Cisco Security Portfolio (9th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
69th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"We use it for malicious connections from malicious websites, to identify payloads that might be inside the traffic, to identify malicious processes or bugs that are running on the network, and any activities that tend to lead to data infiltration."
"I recognize that Cortex XDR by Palo Alto Networks is one of the best products in its category regarding capabilities."
"It's a perfect solution. It integrates well into the environment."
"From a single pane of glass, you can easily manage all of your endpoints."
"Cortex XDR by Palo Alto Networks's ability to block sophisticated threats in real time is quite good and is on par with SentinelOne's."
"The product's most valuable features are massive user and feature intelligence exploit detection."
"The tool is easy to use."
"Cortex XDR is a simple platform that's easy for administrators and users. You have a lot of flexibility to change or customize the features."
"With Cisco Secure Endpoint, we now have visibility over what is happening on the endpoint side."
"The Cisco environment has been perfect."
"It provides real-time visibility and control over endpoints, allowing its users to promptly respond to any security incidents and remediate any vulnerabilities."
"The visibility and insight this solution gives you into threats is pretty granular. It has constant monitoring. You can get onto the device trajectory to look at a threat, but you can also see what happened prior to the threat. You can see what happened after the threat. You can see what other applications were incorporated into the execution of the threat. For example, you have the event, but you see that the event was launched by Google Chrome, which was launched by something else. Then, after the event, something else was launched by whatever the threat was. Therefore, it gives you great detail, a timeline, and continuity of events leading up to whatever the incident is, and then, after. This helps you understand and nail down what the threat is and how to fix it."
"Its most valuable features are its scalability and advanced threat protection for customers."
"If somebody has been compromised, the question always is: How has it affected other devices in the network? Cisco AMP gives you a very neat view of that."
"The simplicity of use is its most valuable feature. You can very clearly see things."
"AMP and the rest of the security stack from Cisco give me peace of mind that the network is taking care of itself and that the endpoints are protected."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"For working with the solution, you only really need a web browser, however, we've found that working on Chrome, for example, is horrible."
"When it comes to malware files, it should be a little quick because, at times, it would give a wrong result in the sense of what it might be on malware, even if it still might be a normal one."
"Cortex XDR is trickier to configure than other Palo Alto products. This is one area where we are not so satisfied."
"It's more focused on network communication. If a customer wants to increase the level of protection and start working with documents, it's impossible to integrate these features into the system. It's more of a communication-oriented system than a content security-oriented system."
"Based on our experience so far, its implementation is quite complex."
"There is also no recovery feature; if some endpoint is under attack there must be the possibility of recovering it or restoring it to a normal state."
"The installation should be easier and the Palo Alto pre-sales and sales teams should have more information on the product because they don't know what they are selling."
"The only issues that we have are, one the cost, two the dashboard is not very intuitive, even though you can drill down within the dashboard, we usually have to gather information from other sources to determine locations and if its a false positive."
"Maybe there is room for improvement in some of the automated remediation."
"Cisco is good in terms of threat intelligence plus machine learning-based solutions, but we feel Cisco is lagging behind in using artificial intelligence in its systems."
"They could improve the main dashboard to more clearly show me the things that I want to see. When I open the dashboard right now, I see a million things and they are not always the things that I need."
"The pricing policy could be more competitive, similar to Cisco's offerings."
"...the greatest value of all, would be to make the security into a single pane of glass. Whilst these products are largely integrated from a Talos perspective, they're not integrated from a portal perspective. For example, we have to look at an Umbrella portal and a separate AMP portal. We also have to look at a separate portal for the firewalls. If I could wave a magic wand and have one thing, I would put all the Cisco products into one, simple management portal."
"It's pretty good as it is, but its cost could be improved."
"In the next version of this solution, I would like to see the addition of local authentication."
"I would like more seamless integration."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"The pricing seems fair, and I do like the licensing model. You use wherever they are, and it is elastic."
"If one wishes to work with another team or large number of users at a future point, he must purchase a license for them."
"I don't recall what the cost was, but it wasn't really that expensive."
"We pay about $50,000 USD per year for a bundle that includes Cortex XDR."
"It has a yearly renewal."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"Every customer has to pay for a license because it doesn't work with what you get from a managed services provider."
"This is an expensive solution."
"In our case, it is a straightforward annual payment through our Enterprise Agreement."
"Licensing fees are on a yearly basis and I am happy with the pricing."
"We have a license for 3,000 users and if we get up to 3,100 users, it doesn't stop working, but on the next renewal date you're supposed to go in there and add that extra 100 licenses. It's really good that they let you grow and expand and then pay for it. Sometimes, with other products, you overuse a license and they just don't work."
"It is a subscription-based product."
"The price is very fair to the customer."
"There are a couple of different consumption models: Pay up front, or if you have an enterprise agreement, you can do a monthly thing. Check your licensing possibilities and see what's best for your organization."
"The solution's price is about the same as that of Palo Alto solutions."
"Whenever you are doing the licensing process, I would highly advise to look at what other Cisco solutions you have in your organization, then evaluate if an Enterprise Agreement is the best way to go. In our case, it was the best way to go. Since we had so many other Cisco products, we were able to tie those in. We were actually able to get several Cisco security solutions for less than if we had bought three or four Cisco security solutions independently or ad hoc."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
10%
Comms Service Provider
9%
Manufacturing Company
10%
Financial Services Firm
8%
Government
7%
Construction Company
7%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise20
Large Enterprise52
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise15
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
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Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What is your primary use case for Cisco Secure Endpoint?
We deployed Cisco Secure Endpoint for our customers two to three years back. The use case was to secure their endpoin...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
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