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Cisco Secure Endpoint vs MetaDefender Endpoint comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 15, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Detection and Response (EDR)
6th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
112
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Cisco Secure Endpoint
Ranking in Endpoint Detection and Response (EDR)
26th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
49
Ranking in other categories
Endpoint Protection Platform (EPP) (29th), Cisco Security Portfolio (9th)
MetaDefender Endpoint
Ranking in Endpoint Detection and Response (EDR)
69th
Average Rating
0.0
Reviews Sentiment
5.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
JavedHashmi - PeerSpot reviewer
Chief Technology Officer at Future Point Technologies
Reliable threat protection is achieved while integration and analysis capabilities need refinement
Cisco Secure Endpoint is very good in machine learning, which allows it to secure offline contents even if not connected to the internet. We haven't encountered a single breach after it's deployed. It controls USB devices and has a separate antivirus solution called Tetra, providing security even for real-time, day-zero attacks through its strong Talos threat intelligence platform.
Jasmit Singh Juneja - PeerSpot reviewer
CEO & Technology Specialist at Karman Infotech Private Limited
Comprehensive endpoint visibility and multilayer security have strengthened compliance and protected removable media in critical environments
I work with the data sanitization feature, including USB. When it comes to data integrity, it is not meant for data integrity; it will modify your data. It will not look into your content, but it will look into embedded objects, such as hyperlinks, scripts, and any other embedded object, macro, and images. It will remove that potential malicious content, sanitize the hyperlink, remove the macro, sanitize the embedded objects, and remove the scripts if they are attached in your document to prevent you from zero-day attacks. MetaDefender Endpoint has an excellent malware detection feature; it has around thirty plus different anti-malware engines, so the detection ratio can go up to ninety-nine point nine percent. The vulnerability assessment feature definitely helps to address system vulnerabilities. You will have visibility of the vulnerability, and it is a continuous assessment. You will get complete visibility of your environment and of your endpoint.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable features are the fact that it was running in the background and it would intercept any weird stuff, and the fact that it would send things directly to the cloud for sandboxing. It's quite practical."
"After deploying Traps, we saw the performance of the network improve by 65 to 70 percent."
"I have found the solution to be very easy in respect of the integration and configurable."
"The most valuable features of this product are the management capabilities, which allow an IT organization to get quite a good picture of attempted cyber attacks, and its out-of-the-box investigation capabilities."
"Palo Alto Networks Traps improves our security posture and lowers risk by providing next-gen methods to combat against modern threats on all the major platforms."
"It's a nice product that's stable and scalable."
"If any application performs suspicious activities, such as changing registries or modifying other applications, Cortex XDR detects and blocks the entire application."
"It's very stable. I've never experienced downtime for the ASM console or ASM core."
"The simplicity of use is its most valuable feature. You can very clearly see things."
"The entirety of our network infrastructure is Cisco and the most valuable feature is the integration."
"The most valuable feature is signature-based malware detection."
"The most valuable feature of the solution is its technical support."
"I did the initial setup myself and it was really easy and straightforward."
"The biggest lesson that I have learned from using this product is that there is a lot more malware slipping through my email filters than I expected."
"Overall, I really liked the product; it was well done."
"It doesn't impact the devices. It is an agent-based solution, and we see no performance knock on cell phones. That was a big thing for us, especially in the mobile world. We don't see battery degradation like you do with other solutions which really drain the battery, as they're constantly doing things. That can shorten the useful life of a device."
"Altogether, it is going to be complete endpoint protection and visibility."
 

Cons

"There's room for improvement with Mac device installations, which can be challenging."
"Cortex XDR by Palo Alto Networks can improve mobile integration to allow access to the console."
"Enhancing UI simplicity and playbook flexibility are areas that could benefit from more low-code automation options for smoother integrations."
"The price could be a little lower."
"The main issue I could point out is the offline agents and the way that it is missing."
"In the next release, I would like to see more UI improvements. Their UI is a bit basic. When we are speaking about Palo Alto Networks they are the big company, so they can improve the UI a little bit. The UI, the reports, the log system can all be improved."
"Cortex XDR could improve its sales support team, including better commission structures and referral programs."
"Limited remote connection."
"The pricing policy could be more competitive, similar to Cisco's offerings."
"I would like more seamless integration."
"We have had some problems with updates not playing nice with our environment. This is important, because if there is a new version, we need to test it thoroughly before it goes into production. We cannot just say, "There's a new version. It's not going to give us any problems." With the complexity of the solution using multiple engines for multiple tasks, it can sometimes cause performance issues on our endpoints. Therefore, we need to test it before we deploy. That takes one to three days before we can be certain that the new version plays nice with our environment."
"In the next version of this solution, I would like to see the addition of local authentication."
"The product does not provide options like tunnel creation or virtual appliances."
"We had a lot of noise at the beginning, and we had to turn it down based on exclusions, application whitelisting, and excluding unknown benign applications. Cisco should understand the need for continuous updates on the custom Cisco exclusions and the custom applications that come out-of-the-box with the AMP for Endpoints."
"The user interface is dull."
"The Linux agent has conflicts with other solutions, including the Exploit Prevention system found in Windows servers, and we didn't find a fix during troubleshooting, and Cisco couldn't offer one either."
"The negative aspect is that it only provides visibility; you require integration with multiple products to get complete control."
 

Pricing and Cost Advice

"I feel it is fairly priced."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"The solution is expensive. It's pricing is on a yearly-basis."
"Compared to CrowdStrike, Cortex XDR is an expensive solution."
"Licensing for Palo Alto Networks Cortex XDR can be costly, especially when it comes to a hundred users. A license is required for each user, and the subscription must be renewed on a yearly basis."
"It is cost-effective compared to similar solutions. It fits for the small businesses through to the big businesses."
"The cost depends on your chosen license type, like Pro or other licenses."
"The solution has one subscription for endpoint protection and one subscription for detection and response. The two licenses combined give you the BRO version."
"It is quite cost-effective. I would rate it ten out of ten."
"The solution is highly affordable; I believe we pay $2 or $3 per endpoint. It's significantly cheaper than the competitors on the market."
"​Pricing can be more expensive than similar software that does less functionality, but not recognized by customers.​"
"The visibility that we have into the endpoint and the forensics that we're able to collect give us value for the price. This is not an overly expensive solution, considering all the things that are provided. You get great performance and value for the cost."
"There are a couple of different consumption models: Pay up front, or if you have an enterprise agreement, you can do a monthly thing. Check your licensing possibilities and see what's best for your organization."
"The pricing and licensing fees are okay."
"Whenever you are doing the licensing process, I would highly advise to look at what other Cisco solutions you have in your organization, then evaluate if an Enterprise Agreement is the best way to go. In our case, it was the best way to go. Since we had so many other Cisco products, we were able to tie those in. We were actually able to get several Cisco security solutions for less than if we had bought three or four Cisco security solutions independently or ad hoc."
"My company does make annual payments towards the licensing costs of the solution. Cisco Secure Endpoint is a little bit expensive."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
10%
Comms Service Provider
9%
Manufacturing Company
10%
Financial Services Firm
8%
Government
7%
Construction Company
7%
No data available
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise20
Large Enterprise52
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise15
Large Enterprise21
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Cisco Secure Endpoint?
Cisco is aggressive in pricing, making it competitive and sometimes even cheaper than other good products like CrowdS...
What needs improvement with Cisco Secure Endpoint?
Cisco Secure Endpoint lacks features like DLP which other vendors offer. XDR is new, so integration capabilities with...
What is your primary use case for Cisco Secure Endpoint?
We deployed Cisco Secure Endpoint for our customers two to three years back. The use case was to secure their endpoin...
What needs improvement with MetaDefender Endpoint?
The negative aspect is that it only provides visibility; you require integration with multiple products to get comple...
What is your primary use case for MetaDefender Endpoint?
There are multiple use cases for MetaDefender Endpoint. The main one is a compliance check and system compliance chec...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Cisco AMP for Endpoints
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Heritage Bank, Mobile County Schools, NHL University, Thunder Bay Regional, Yokogawa Electric, Sam Houston State University, First Financial Bank
Information Not Available
Find out what your peers are saying about CrowdStrike, SentinelOne, Microsoft and others in Endpoint Detection and Response (EDR). Updated: June 2026.
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