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Cisco Secure Workload vs Microsoft Defender for Cloud comparison

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Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Cloud Workload Protection Platforms (CWPP)
8th
Average Rating
8.6
Reviews Sentiment
7.1
Number of Reviews
46
Ranking in other categories
Vulnerability Management (11th), Container Security (11th), Cloud Security Posture Management (CSPM) (8th), SaaS Security Posture Management (SSPM) (2nd), Cloud-Native Application Protection Platforms (CNAPP) (7th)
Cisco Secure Workload
Ranking in Cloud Workload Protection Platforms (CWPP)
18th
Average Rating
8.6
Reviews Sentiment
7.7
Number of Reviews
15
Ranking in other categories
Cloud and Data Center Security (8th), Microsegmentation Software (4th), Cisco Security Portfolio (8th)
Microsoft Defender for Cloud
Ranking in Cloud Workload Protection Platforms (CWPP)
1st
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
89
Ranking in other categories
Vulnerability Management (6th), Container Management (6th), Container Security (4th), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (6th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (3rd)
 

Mindshare comparison

As of September 2026, in the Cloud Workload Protection Platforms (CWPP) category, the mindshare of Qualys TotalCloud is 1.8%, up from 1.3% compared to the previous year. The mindshare of Cisco Secure Workload is 2.0%, down from 2.7% compared to the previous year. The mindshare of Microsoft Defender for Cloud is 10.7%, down from 14.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Cloud Workload Protection Platforms (CWPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Cloud10.7%
Qualys TotalCloud1.8%
Cisco Secure Workload2.0%
Other85.5%
Cloud Workload Protection Platforms (CWPP)
 

Featured Reviews

reviewer2859021 - PeerSpot reviewer
Sr Security Engineer at a tech vendor with 5,001-10,000 employees
Risk-based triage has transformed container security and now prioritizes high-impact threats
The best features Qualys TotalCloud offers currently include managing cloud infrastructure and container security while facing major challenges such as alert fatigue. Traditional vulnerability scanners flag hundreds of CVEs on short-lived Kubernetes containers, some of which have no internet exposure or are gone before we can even triage them. I leverage Qualys TotalCloud to move beyond static CVSS. I use it to implement runtime exposure, correlation risk reprioritization, and shift-left integration. This notifies developers to fix a base image upstream rather than patching live ephemeral instances. In my work with cloud and container security, the biggest operational hurdle was alert fatigue. I use Qualys to shift left from static CVSS severity to context-aware risk prioritization. I correlated raw vulnerability data with real-time risk factors such as public network exposure, active runtime execution, or overly permissive IAM roles. This allows us to immediately drop the priority of isolated containers and escalate lower-severity CVEs that sit on an exposed, high-risk path. We can map these findings directly back to our CI/CD pipelines so developers can patch the root base images upstream. We have drastically cut down the signal-to-noise ratio, saved a lot of manual hours doing triage work, and ensured engineering effort goes directly towards high-impact risk reduction.
Raj Metkar - PeerSpot reviewer
Director, Head of Networks at MUFG, EMEA
Discover internal application dependencies and create a dependency map
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration allows Cisco Secure Workload to learn about our networks and network tags, providing valuable insights into vulnerabilities related to the operating system and various applications installed on our servers. Recently, Cisco announced a new product called HyperShield, an AI-based autonomous micro-segmentation solution. While Cisco has not stated that HyperShield will replace Cisco Secure Workload, it represents a natural evolution for the company. HyperShield features dynamic policy discovery and enforcement; however, once policies are enforced, they do not change until a discovery occurs, requiring a re-enforcement process. This new platform operates autonomously, minimizing the need for user or security engineer intervention. I would have expected Cisco to incorporate more automatic discovery and enforcement features within the existing Cisco Secure Workload product. Instead of enhancing the current product, they have introduced a new solution. Cisco plans to honor existing Tetration licenses, allowing users to transition to HyperShield without additional costs, reflecting the investment enterprises have already made. From Cisco’s perspective, this represents a natural progression in their product line. While the product name changes, it seems more of a rebranding effort. The enhancements are greater autonomy, improved discovery, and automatic enforcement, which are now being introduced in HyperShield. Cisco Secure Workload offers automatic policy enforcement but cannot adjust policies dynamically as the application needs to change. Having used the platform for the past five years, the recent announcement has been reassuring. Cisco has confirmed that our investment in the platform will not go to waste. They will honor our existing licenses, providing a natural migration path to the new solution without any disruption
RW
Head Of IT at Cirrus Response
Cloud security has cut investigation time and now reveals threats faster but needs simpler oversight
When deploying AI applications, my key security concerns with Microsoft Defender for Cloud are data loss, leakage of data, and guardrails around the actual AI, and I am hoping that this is going to help me put those guardrails in place and identify data exfiltration. Microsoft Defender for Cloud has not helped me manage and secure multi-cloud environments, as we are 100 percent Microsoft and have not really got it in any other environment at all. I am not yet using the unified AI-powered security feature offered by Microsoft Defender for Cloud, but that is coming. I am not yet using the integrated XDR feature of Microsoft Defender for Cloud, but that is coming. I am not yet utilizing the GenAI threat protection features of Microsoft Defender for Cloud. That is also coming and a lot of that will come from learning it here. I have enabled the agentless scanning in my cloud environment with Microsoft Defender for Cloud. Assessing the impact on my workload protection without needing to install agents with Microsoft Defender for Cloud makes it a lot easier, but it also identifies a lot more, which puts more load on me sometimes. I would advise another organization considering Microsoft Defender for Cloud that it is the most logical route to follow if their whole ecosystem is Microsoft. It is easy to implement and it is very self-explanatory when doing it, making sense to just follow the steps as it is too simple, really. I would rate this review a 7.5 out of 10.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I like the web API security and IoT scanning features the most. The user-friendly design of TotalCloud's interface enables customers to navigate it and use its full potential easily"
"One of the features I appreciate is the ability to generate daily reports without relying on anyone else."
"Qualys TotalCloud's most valuable feature is its agent versatility."
"Vulnerability and threat detection and assessment of the criticality of the vulnerabilities exposed are most valuable."
"Qualys TotalCloud has helped us view our risk structure, vulnerabilities, and security posture."
"I highly recommend Qualys TotalCloud to other users."
"TotalCloud has been excellent in providing us with immediate access to all the products and features we need, such as CSPM, TruRisk Insights, and compliance reports, including CIS and HIPAA."
"If someone were to ask me to review Qualys TotalCloud, I would summarize it as an end-to-end solution for cloud security with visibility and governance-grade controls without needing to manage multiple disconnected tools."
"The solution is very user-friendly, which clients appreciate."
"Scalability is its most valuable feature."
"A complete and powerful micro-segmentation solution."
"The scalability of Cisco Tetration is very good."
"By using Tetration insight, we are able to get the latency on our level accounts and we can determine whatever the issue is with the application latency itself."
"The solution offers 100% telemetry coverage; the telemetry you collect is not sampled, it's not intermittent, it's complete, and you see everything in it, including full visibility of all activities on your endpoints and in your network."
"The most valuable feature of the solution is that we don't have to do packet captures on the network."
"The product offers great visibility into the network so we can enforce security measures."
"I appreciate the features of Microsoft Defender for Cloud the most because it incorporates itself into the entire Microsoft platform, and it's a one-stop shop for administration in the web."
"The solution is very easy to deploy."
"With respect to improving our security posture, it helps us to understand where we are in terms of compliance. We can easily know when we are below the standard because of the scores it calculates."
"For any type of service, I would recommend the go-to solution for security on Azure is Security Center."
"The UX and UI are very good. Users have more of a taste for Microsoft UI."
"Good compliance policies."
"Azure Security Center has helped to improve our security posture."
"Threat protection is comprehensive and simple."
 

Cons

"To be honest, I would move out from this tool because it does not give a full view of vulnerability."
"The areas in the solution that have room for improvement include the UI/UX design, which should be improved, and they should integrate more artificial intelligence into the product."
"Qualys' customer service provides quality answers, but the response time is long, even though it is within the SLA."
"The onboarding process is a bit difficult. In the initial phase, it is very difficult to understand the features, what the dashboard contains, and what criteria they are using."
"The vulnerability part is good, but the policy compliance module needs improvement because it involves a lot of manual work. Specifically, the remediation part of the controls requires enhancements."
"I would like the ability to disable certain default built-in policies as they can be misleading when creating dashboards. That is the top one."
"An area for improvement would be to focus on risks related to AI, such as large language models and potential data leakage."
"Two areas for improvement in Qualys TotalCloud are the speed of the public cloud platform and vulnerability detection."
"The multi-tenancy, redundancy, backup and restore functionalities, as well as the monitoring aspects of the solution, need improvement. The solution offers virtually no enterprise-grade possibility for monitoring."
"There is some overlap between Cisco Tetration and AppDynamics and there are few DC tools, it would be great to have a single pane of glass, rather than have to jump between different tools."
"It is not so easy to use and configure. It needs a bunch of further resources to work, which is mainly the biggest downside of it. The deployment is huge."
"The problem is that we can only deploy the particular solution where we have the hardware with Cisco."
"The product must be integrated with the cloud."
"It is highly scalable, but there is a limitation that it is only available on Cisco devices."
"Cisco Tetration needs more flags and system alerts that we should get with network capture."
"Secure Workload is a little complicated to use, and the dashboard isn't intuitive, so it takes a while to learn how to use it."
"Microsoft Defender for Cloud is not compatible with Linux machines."
"We haven't experienced issues with Microsoft Defender for Cloud for our company size of about five hundred people. However, I've heard there might be issues with scalability for larger enterprises."
"With the new Copilot functionality available everywhere, it is challenging to pinpoint areas for improvement. If I put in a lot of thought, I might identify things, but right now, nothing significant pops into my mind, but there is always room for more transparency, especially in pricing."
"Defender could provide more in-depth visibility into vulnerabilities and services. For instance, we wanted to scan Azure NetApp for sensitive data, but they didn't have that feature. It was only for storage accounts. I want Azure Defender features to cover all Azure resources rather than a few."
"It's very expensive in terms of the need to maintain it actively."
"The amount billed for the amount of terabytes you're scanning is too high and will lead into security risks if somebody is limiting the amount of data to be scanned based on the cost, so this is something I would prefer to be changed."
"Features like code scanning and pipeline scanning are not included in the solution."
"Azure is a complex solution. You have so many moving parts."
 

Pricing and Cost Advice

"Qualys TotalCloud is cost-efficient and was selected for its value compared to other products."
"Qualys TotalCloud is expensive."
"TotalCloud's price is about right where I would expect it to be."
"Qualys TotalCloud is expensive, but it offers a premier solution with no headaches."
"Qualys TotalCloud offers competitive pricing given its comprehensive suite of features, including integration, assessment, remediation, and detection capabilities, all within a single platform."
"The pricing is comparable. It is built into our other product, so I cannot piecemeal it. It is a part of our subscription."
"Qualys TotalCloud offers good pricing that is affordable and competitive with the market. Our partnership also provides us with additional benefits."
"I am not sure about the pricing. From what I understand, it is a bit on the higher side, but I do not have the exact numbers."
"The pricing is a bit higher than we anticipated."
"Regarding price, Cisco Secure Workload can be expensive if you don't have a budget. If you're not doing micro-segmentation, every extra security measure or enforcement you're putting on top of your existing environment will be an extra cost. It's not a cheap solution at all. But from my point of view, if you need to do micro-segmentation, this is one of the best tools I've seen for it. I can't compare that to Microsoft's solution because I haven't looked into it. I've looked into VMware and Cisco. Those are the only two that I know of. I didn't know that Microsoft could do micro-segmentation at all. Maybe they can, but I haven't heard anything about it."
"The price is based on how many computers you're going to install it on."
"Pricing depends on the scope of the application and the features. Larger installations save more."
"The cost for the hardware is around 300k."
"It is not cheap and pricing may limit scalability."
"The price is outrageous. If you have money to throw at the product, then do it."
"The pricing and licensing of Microsoft Defender for Cloud have been good for us. We appreciate the licensing approach based on employee count rather than a big enterprise license."
"The price of the solution is good for the features we receive and there is an additional cost for Microsoft premier support. However, some of my potential customers have found it to be expensive and have gone on to choose another solution."
"The pricing model for most plans is generally good, but the cost of the new Defender for Storage plan is high and should be revisited, as it could lead to disabling desirable security features due to cost."
"I rate Microsoft Defender a three out of ten for affordability. The price could be a little lower."
"There is a helpful cost-reducing option that allows you to integrate production subscriptions with non-production subscriptions."
"We are using the free version of the Azure Security Center."
"Pricing depends on your workload size, but it is very cheap. If you're talking about virtual machines, it is $5 or something for each machine, which is minimal. If you go for some agent-based solution for every virtual machine, then you need to pay the same thing or more than that. For an on-premises solution like this, we were paying around $30 to $50 based on size. With Defender, Microsoft doesn't bother about the size. You pay based on the number of machines. So, if you have 10 virtual machines, and 10 virtual machines are being monitored, you are paying based on that rather than the size of the virtual machine. Thus, you are paying for the number of units rather than paying for the size of your units."
"This is a worldwide service and depending on the country, there will be different prices."
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Top Industries

By visitors reading reviews
Comms Service Provider
16%
Outsourcing Company
12%
Manufacturing Company
11%
Financial Services Firm
10%
Manufacturing Company
13%
Financial Services Firm
9%
Government
8%
Outsourcing Company
8%
Financial Services Firm
11%
Computer Software Company
10%
Manufacturing Company
8%
Outsourcing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business14
Midsize Enterprise5
Large Enterprise34
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise3
Large Enterprise8
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise12
Large Enterprise49
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
In terms of improvement, remediation still belongs to the cloud team, which is one of the issues we faced with Qualys...
What is your primary use case for Qualys TotalCloud?
My main use case for Qualys TotalCloud is regarding the cloud visibility that we were not having previously. Previous...
What is your experience regarding pricing and costs for Cisco Secure Workload?
CloudStrike offers antivirus capabilities and firewall features for servers and VDI but lacks automatic policy discov...
What needs improvement with Cisco Secure Workload?
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration a...
What is your primary use case for Cisco Secure Workload?
When we onboarded Cisco Secure Workload, the usual use case was to discover internal application dependencies and cre...
How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening acros...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup costs, and licensing was that the license cost was the only consideration. Setup an...
What needs improvement with Microsoft Defender for Cloud?
To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an inges...
 

Also Known As

Qualys TotalCloud with FlexScan
Cisco Tetration
Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

Information Not Available
ADP, University of North Carolina Charlotte (UNCC)
Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Find out what your peers are saying about Cisco Secure Workload vs. Microsoft Defender for Cloud and other solutions. Updated: September 2026.
913,683 professionals have used our research since 2012.