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Cisco Secure Workload vs Microsoft Defender for Cloud comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Cloud Workload Protection Platforms (CWPP)
8th
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
39
Ranking in other categories
Vulnerability Management (11th), Container Security (11th), Cloud Security Posture Management (CSPM) (8th), SaaS Security Posture Management (SSPM) (1st), Cloud-Native Application Protection Platforms (CNAPP) (6th)
Cisco Secure Workload
Ranking in Cloud Workload Protection Platforms (CWPP)
16th
Average Rating
8.6
Reviews Sentiment
7.7
Number of Reviews
15
Ranking in other categories
Cloud and Data Center Security (7th), Microsegmentation Software (4th), Cisco Security Portfolio (8th)
Microsoft Defender for Cloud
Ranking in Cloud Workload Protection Platforms (CWPP)
1st
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
89
Ranking in other categories
Vulnerability Management (5th), Container Management (7th), Container Security (4th), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (4th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (3rd)
 

Mindshare comparison

As of June 2026, in the Cloud Workload Protection Platforms (CWPP) category, the mindshare of Qualys TotalCloud is 1.5%, up from 1.2% compared to the previous year. The mindshare of Cisco Secure Workload is 2.1%, down from 3.0% compared to the previous year. The mindshare of Microsoft Defender for Cloud is 13.2%, down from 13.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Cloud Workload Protection Platforms (CWPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Cloud13.2%
Qualys TotalCloud1.5%
Cisco Secure Workload2.1%
Other83.2%
Cloud Workload Protection Platforms (CWPP)
 

Featured Reviews

RO
IT Security Expert at Alior Bank S.A.
Unified risk scoring has improved our cloud visibility and simplifies remediation priorities
Qualys TotalCloud provides unified vulnerability and threat assessment across both IAS and SaaS. This solution provides a single prioritized view of risk, which helps reduce the work I would have to do. We are no longer based on CVSS; we are based on Qualys risk scoring, which is based on CVSS plus internal findings made by Qualys, and then assigns its own score. The TruRisk insight feature has found a small number of assets with high vulnerability scores, though I am cautious since some information is classified. Qualys TotalCloud has positively impacted our bank's performance, and we have definitely seen benefits after implementing this solution.
Raj Metkar - PeerSpot reviewer
Director, Head of Networks at MUFG, EMEA
Discover internal application dependencies and create a dependency map
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration allows Cisco Secure Workload to learn about our networks and network tags, providing valuable insights into vulnerabilities related to the operating system and various applications installed on our servers. Recently, Cisco announced a new product called HyperShield, an AI-based autonomous micro-segmentation solution. While Cisco has not stated that HyperShield will replace Cisco Secure Workload, it represents a natural evolution for the company. HyperShield features dynamic policy discovery and enforcement; however, once policies are enforced, they do not change until a discovery occurs, requiring a re-enforcement process. This new platform operates autonomously, minimizing the need for user or security engineer intervention. I would have expected Cisco to incorporate more automatic discovery and enforcement features within the existing Cisco Secure Workload product. Instead of enhancing the current product, they have introduced a new solution. Cisco plans to honor existing Tetration licenses, allowing users to transition to HyperShield without additional costs, reflecting the investment enterprises have already made. From Cisco’s perspective, this represents a natural progression in their product line. While the product name changes, it seems more of a rebranding effort. The enhancements are greater autonomy, improved discovery, and automatic enforcement, which are now being introduced in HyperShield. Cisco Secure Workload offers automatic policy enforcement but cannot adjust policies dynamically as the application needs to change. Having used the platform for the past five years, the recent announcement has been reassuring. Cisco has confirmed that our investment in the platform will not go to waste. They will honor our existing licenses, providing a natural migration path to the new solution without any disruption
RW
Head Of IT at Cirrus Response
Cloud security has cut investigation time and now reveals threats faster but needs simpler oversight
When deploying AI applications, my key security concerns with Microsoft Defender for Cloud are data loss, leakage of data, and guardrails around the actual AI, and I am hoping that this is going to help me put those guardrails in place and identify data exfiltration. Microsoft Defender for Cloud has not helped me manage and secure multi-cloud environments, as we are 100 percent Microsoft and have not really got it in any other environment at all. I am not yet using the unified AI-powered security feature offered by Microsoft Defender for Cloud, but that is coming. I am not yet using the integrated XDR feature of Microsoft Defender for Cloud, but that is coming. I am not yet utilizing the GenAI threat protection features of Microsoft Defender for Cloud. That is also coming and a lot of that will come from learning it here. I have enabled the agentless scanning in my cloud environment with Microsoft Defender for Cloud. Assessing the impact on my workload protection without needing to install agents with Microsoft Defender for Cloud makes it a lot easier, but it also identifies a lot more, which puts more load on me sometimes. I would advise another organization considering Microsoft Defender for Cloud that it is the most logical route to follow if their whole ecosystem is Microsoft. It is easy to implement and it is very self-explanatory when doing it, making sense to just follow the steps as it is too simple, really. I would rate this review a 7.5 out of 10.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Qualys TotalCloud fulfills all these needs."
"The most valuable feature is the consolidated information that it provides from various platforms."
"If someone were to ask me to review Qualys TotalCloud, I would summarize it as an end-to-end solution for cloud security with visibility and governance-grade controls without needing to manage multiple disconnected tools."
"The most valuable feature is extensibility."
"Its dashboards are brilliant. It provides in-depth insights."
"Qualys TotalCloud has improved our security posture."
"I highly recommend Qualys TotalCloud to other users."
"I would rate Qualys TotalCloud ten out of ten."
"The product offers great visibility into the network so we can enforce security measures."
"The solution offers 100% telemetry coverage; the telemetry you collect is not sampled, it's not intermittent, it's complete, and you see everything in it, including full visibility of all activities on your endpoints and in your network."
"A complete and powerful micro-segmentation solution."
"The scalability of Cisco Tetration is very good."
"Secure Workload's best feature is that it's an end-to-end offering from Cisco."
"The most valuable feature right now is to do with having visibility on the network — especially on our servers — and to be able to enforce some type of security measures."
"The solution is very user-friendly, which clients appreciate."
"The only use case I can see that makes sense is micro-segmentation. I think there are other use cases for it. The main purpose of the product is to do micro-segmentation by collecting IP. That could be done by installing an agent, and then you have all the communication coming in and out. You could also use some flow sensors installed in the network that receive a copy of the traffic and then report that back to the system."
"Good compliance policies."
"This solution has the best security center, security manager dashboard that I have ever seen."
"It's got a lot of great features."
"Microsoft Defender for Cloud helps in improving our overall security posture. We have a nice overview of what is missing where and what can be improved."
"Defender for Cloud has improved our security posture, providing us with a prioritized list of security issues to remedy, which improves our security operations because we know what to tackle first."
"The solution's coordinated detection and response across devices and identities is impressive because it is complete."
"The integration with Logic Apps allows for automated responses to incidents."
"The product has given us more insight into potential avenues for attack paths."
 

Cons

"The price is very expensive, actually."
"With the growing integration of AI, I would like Qualys to enhance its service offerings to better accommodate AI-related risks."
"Overall, we are satisfied with it. However, the response part of the Cloud Detection and Response (CDR) module can be improved. It is not yet in place according to requirements; it is not completely available even though the module has been released."
"There is room for improvement in the support."
"We would like to see Windows-based sensors available in Qualys, as this would make the platform more versatile and support a broader range of environments."
"We encountered challenges identifying the correct resource category for certain items, such as those in containers or storage."
"TotalCloud could improve the classification of vulnerabilities. Specifically, it could enhance the categorization of what aspects fall under patches resolved by OS or software updates and what pertains to configuration adjustments."
"From a downside perspective, the UI is not user-friendly and feels dated compared to other tools like Prisma Cloud."
"There's room for improvement when it comes to Cisco Secure Workload. A couple of internal areas could be refined a little bit. They are trying to solve it, depending on where you suppose the agent is. Suppose you have the agent on both the server and the client, which could be the front-end server or web server connecting to the. In that case, if those two are communicating on RPC, the server can look into its configuration. It could go down and find the configuration file on the FTP server and then set the policies to it. But there are a lot of different FTP servers out there. It's also a complex case for the tool to support all FTP servers."
"The multi-tenancy, redundancy, backup and restore functionalities, as well as the monitoring aspects of the solution, need improvement. The solution offers virtually no enterprise-grade possibility for monitoring."
"The interface is really helpful for technical people, but it is not user-friendly."
"It has an uninviting interface."
"I'd like to see better documentation for advanced features. The documentation is fairly basic. I would also like to see better integration with other applications."
"Cisco Tetration needs more flags and system alerts that we should get with network capture."
"The emailed notifications are either hard to find or they are not available. Search capabilities can be improved."
"It is not so easy to use and configure. It needs a bunch of further resources to work, which is mainly the biggest downside of it. The deployment is huge."
"Agent features need to be improved. Sometimes, we are not able to get correct signals from the machines on which we have installed these agents."
"I rate Microsoft support five out of 10. It gets better once you're escalated past the first and second levels. It's difficult to get the necessary support when tickets are first opened."
"The solution could improve by being more intuitive and easier to use requiring less technical knowledge."
"The remediation process could be improved."
"The vulnerabilities are duplicated many times."
"Azure Security Center should be more easily understood by a non-technical person. It needs to be simplified and made more user-friendly for a non-technical person."
"From my own perspective, they just need a product that is tailored to micro-segmentation so I can configure rules for multiple systems at once and manage it."
"Most customer teams need more training on this type of product."
 

Pricing and Cost Advice

"Qualys TotalCloud offers good pricing that is affordable and competitive with the market. Our partnership also provides us with additional benefits."
"Qualys TotalCloud is expensive."
"Its price seems higher compared to other tools, but it is worth it. If they could adjust the pricing and make it comparable with other tools, that would be great."
"I am not sure about the pricing. From what I understand, it is a bit on the higher side, but I do not have the exact numbers."
"TotalCloud's price is about right where I would expect it to be."
"Qualys TotalCloud is expensive, but it offers a premier solution with no headaches."
"Qualys TotalCloud offers competitive pricing given its comprehensive suite of features, including integration, assessment, remediation, and detection capabilities, all within a single platform."
"The cost is high, but it meets our organizational needs."
"It is not cheap and pricing may limit scalability."
"Pricing depends on the scope of the application and the features. Larger installations save more."
"Regarding price, Cisco Secure Workload can be expensive if you don't have a budget. If you're not doing micro-segmentation, every extra security measure or enforcement you're putting on top of your existing environment will be an extra cost. It's not a cheap solution at all. But from my point of view, if you need to do micro-segmentation, this is one of the best tools I've seen for it. I can't compare that to Microsoft's solution because I haven't looked into it. I've looked into VMware and Cisco. Those are the only two that I know of. I didn't know that Microsoft could do micro-segmentation at all. Maybe they can, but I haven't heard anything about it."
"The pricing is a bit higher than we anticipated."
"The price is based on how many computers you're going to install it on."
"The cost for the hardware is around 300k."
"The price is outrageous. If you have money to throw at the product, then do it."
"The product's pricing policy is generally favorable."
"Currently, Microsoft offers only one plan at the enterprise level which is $15 per machine."
"The pricing is very difficult because every type of Defender for Cloud has its own metrics and pricing. If you have Cloud for Key Vault, the pricing is different than it is for storage. Every type has its own pricing list and rules."
"Defender for Cloud is pretty costly for a single line. It's incredibly high to pay monthly for security per server. The cost is considerable for an enterprise with 500-plus virtual machines, and the monthly bill can spike."
"The price of the solution is good for the features we receive and there is an additional cost for Microsoft premier support. However, some of my potential customers have found it to be expensive and have gone on to choose another solution."
"Security Center charges $15 per resource for any workload that you onboard into it. They charge per VM or per data-base server or per application. It's not like Microsoft 365 licensing, where there are levels like E3 and E5. Security Center is pretty straightforward."
"There are improvements that have to be made to the licensing. Currently, for servers, it has to be done by grouping the servers on a single subscription... We don't have an option whereby, if all those resources are in one subscription, we can have each of the individual servers subject to different planning."
"I'm not privy to that information, but I know it's probably close to a million dollars a year."
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Top Industries

By visitors reading reviews
Manufacturing Company
18%
Financial Services Firm
14%
Construction Company
7%
Comms Service Provider
7%
Manufacturing Company
14%
Financial Services Firm
10%
Government
9%
Computer Software Company
8%
Financial Services Firm
12%
Computer Software Company
10%
Manufacturing Company
9%
Government
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise3
Large Enterprise29
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise3
Large Enterprise8
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise12
Large Enterprise49
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
Areas that need improvement in every solution include the remediation part. The remediation steps should be simple en...
What is your primary use case for Qualys TotalCloud?
Our use case involves the assets that we have under cloud, the assets exposed to the internet, and the internal appli...
What is your experience regarding pricing and costs for Cisco Secure Workload?
CloudStrike offers antivirus capabilities and firewall features for servers and VDI but lacks automatic policy discov...
What needs improvement with Cisco Secure Workload?
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration a...
What is your primary use case for Cisco Secure Workload?
When we onboarded Cisco Secure Workload, the usual use case was to discover internal application dependencies and cre...
How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening acros...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup costs, and licensing was that the license cost was the only consideration. Setup an...
What needs improvement with Microsoft Defender for Cloud?
To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an inges...
 

Also Known As

Qualys TotalCloud with FlexScan
Cisco Tetration
Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

Information Not Available
ADP, University of North Carolina Charlotte (UNCC)
Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Find out what your peers are saying about Cisco Secure Workload vs. Microsoft Defender for Cloud and other solutions. Updated: June 2026.
900,644 professionals have used our research since 2012.