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Cisco Secure Workload vs Microsoft Defender for Cloud comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Cloud Workload Protection Platforms (CWPP)
8th
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
39
Ranking in other categories
Vulnerability Management (11th), Container Security (11th), Cloud Security Posture Management (CSPM) (8th), SaaS Security Posture Management (SSPM) (1st), Cloud-Native Application Protection Platforms (CNAPP) (6th)
Cisco Secure Workload
Ranking in Cloud Workload Protection Platforms (CWPP)
16th
Average Rating
8.6
Reviews Sentiment
7.7
Number of Reviews
15
Ranking in other categories
Cloud and Data Center Security (7th), Microsegmentation Software (4th), Cisco Security Portfolio (8th)
Microsoft Defender for Cloud
Ranking in Cloud Workload Protection Platforms (CWPP)
1st
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
89
Ranking in other categories
Vulnerability Management (5th), Container Management (7th), Container Security (4th), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (4th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (3rd)
 

Mindshare comparison

As of June 2026, in the Cloud Workload Protection Platforms (CWPP) category, the mindshare of Qualys TotalCloud is 1.5%, up from 1.2% compared to the previous year. The mindshare of Cisco Secure Workload is 2.1%, down from 3.0% compared to the previous year. The mindshare of Microsoft Defender for Cloud is 13.2%, down from 13.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Cloud Workload Protection Platforms (CWPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Cloud13.2%
Qualys TotalCloud1.5%
Cisco Secure Workload2.1%
Other83.2%
Cloud Workload Protection Platforms (CWPP)
 

Featured Reviews

RO
IT Security Expert at Alior Bank S.A.
Unified risk scoring has improved our cloud visibility and simplifies remediation priorities
Qualys TotalCloud provides unified vulnerability and threat assessment across both IAS and SaaS. This solution provides a single prioritized view of risk, which helps reduce the work I would have to do. We are no longer based on CVSS; we are based on Qualys risk scoring, which is based on CVSS plus internal findings made by Qualys, and then assigns its own score. The TruRisk insight feature has found a small number of assets with high vulnerability scores, though I am cautious since some information is classified. Qualys TotalCloud has positively impacted our bank's performance, and we have definitely seen benefits after implementing this solution.
Raj Metkar - PeerSpot reviewer
Director, Head of Networks at MUFG, EMEA
Discover internal application dependencies and create a dependency map
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration allows Cisco Secure Workload to learn about our networks and network tags, providing valuable insights into vulnerabilities related to the operating system and various applications installed on our servers. Recently, Cisco announced a new product called HyperShield, an AI-based autonomous micro-segmentation solution. While Cisco has not stated that HyperShield will replace Cisco Secure Workload, it represents a natural evolution for the company. HyperShield features dynamic policy discovery and enforcement; however, once policies are enforced, they do not change until a discovery occurs, requiring a re-enforcement process. This new platform operates autonomously, minimizing the need for user or security engineer intervention. I would have expected Cisco to incorporate more automatic discovery and enforcement features within the existing Cisco Secure Workload product. Instead of enhancing the current product, they have introduced a new solution. Cisco plans to honor existing Tetration licenses, allowing users to transition to HyperShield without additional costs, reflecting the investment enterprises have already made. From Cisco’s perspective, this represents a natural progression in their product line. While the product name changes, it seems more of a rebranding effort. The enhancements are greater autonomy, improved discovery, and automatic enforcement, which are now being introduced in HyperShield. Cisco Secure Workload offers automatic policy enforcement but cannot adjust policies dynamically as the application needs to change. Having used the platform for the past five years, the recent announcement has been reassuring. Cisco has confirmed that our investment in the platform will not go to waste. They will honor our existing licenses, providing a natural migration path to the new solution without any disruption
RW
Head Of IT at Cirrus Response
Cloud security has cut investigation time and now reveals threats faster but needs simpler oversight
When deploying AI applications, my key security concerns with Microsoft Defender for Cloud are data loss, leakage of data, and guardrails around the actual AI, and I am hoping that this is going to help me put those guardrails in place and identify data exfiltration. Microsoft Defender for Cloud has not helped me manage and secure multi-cloud environments, as we are 100 percent Microsoft and have not really got it in any other environment at all. I am not yet using the unified AI-powered security feature offered by Microsoft Defender for Cloud, but that is coming. I am not yet using the integrated XDR feature of Microsoft Defender for Cloud, but that is coming. I am not yet utilizing the GenAI threat protection features of Microsoft Defender for Cloud. That is also coming and a lot of that will come from learning it here. I have enabled the agentless scanning in my cloud environment with Microsoft Defender for Cloud. Assessing the impact on my workload protection without needing to install agents with Microsoft Defender for Cloud makes it a lot easier, but it also identifies a lot more, which puts more load on me sometimes. I would advise another organization considering Microsoft Defender for Cloud that it is the most logical route to follow if their whole ecosystem is Microsoft. It is easy to implement and it is very self-explanatory when doing it, making sense to just follow the steps as it is too simple, really. I would rate this review a 7.5 out of 10.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"I would rate Qualys TotalCloud ten out of ten."
"Qualys TotalCloud has significantly improved our organization by automating our reporting processes, reducing the time spent on report creation from two hours to less than fifteen to twenty minutes."
"The platform's unified view of the organization proves particularly valuable for leadership team meetings."
"Its dashboards are brilliant. It provides in-depth insights."
"If someone were to ask me to review Qualys TotalCloud, I would summarize it as an end-to-end solution for cloud security with visibility and governance-grade controls without needing to manage multiple disconnected tools."
"The agent and agentless scanning in TotalCloud, particularly the FlexScan method, is incredibly valuable. With traditional scanning approaches, we had to give IP ranges and whitelist IPs. All that is now simplified. FlexScan requires minimal intervention, and after configuration, it automatically collects data and performs necessary scans."
"Qualys TotalCloud has improved our security posture."
"One of the most valuable features of Qualys TotalCloud is FlexScan, which is specifically for internet-facing VMs. We found this feature to be very useful. It was a key differentiator for us."
"The most valuable feature of the solution is that we don't have to do packet captures on the network."
"The most valuable feature right now is to do with having visibility on the network — especially on our servers — and to be able to enforce some type of security measures."
"Secure Workload's best feature is that it's an end-to-end offering from Cisco."
"A complete and powerful micro-segmentation solution."
"The solution offers 100% telemetry coverage; the telemetry you collect is not sampled, it's not intermittent, it's complete, and you see everything in it, including full visibility of all activities on your endpoints and in your network."
"Generally speaking, Cisco support is considered one of the best in the networking products and stack."
"This product does everything that you need it to do and more and does a lot to provide visibility in a network environment, save time and money, and make the organization IT operate in a much more streamlined fashion."
"The only use case I can see that makes sense is micro-segmentation. I think there are other use cases for it. The main purpose of the product is to do micro-segmentation by collecting IP. That could be done by installing an agent, and then you have all the communication coming in and out. You could also use some flow sensors installed in the network that receive a copy of the traffic and then report that back to the system."
"It is very intuitive when it comes to policy administration, alerts and notifications, and ease of setting up roles at different hierarchies. It has also been good in terms of the network technology maps. It provides a good overview, but it also depends on the complexity of your network."
"It helps you to identify the gaps in your solution and remediate them, and it produces a compliance checklist against known standards such as ISO 27001, HIPAA, iTrust, etc."
"Threat protection is comprehensive and simple."
"The technical support is very good."
"Some of the most valuable features of Microsoft Defender for Cloud include its effectiveness in threat detection through unsupervised machine learning, CTI, and advanced sandboxing."
"The most valuable features are the monitoring of users, endpoint detection and response, and the adaptability of the AI threat intelligence engine, which quickly adapts to customizations."
"The most valuable features are ransomware protection and access controls. The solution has helped us secure some folders on our systems from unauthorized modifications."
"It improves the transparency and visibility of the traffic in and out of the network of each workload on my system."
 

Cons

"We encountered challenges identifying the correct resource category for certain items, such as those in containers or storage."
"The price is very expensive, actually."
"Although TotalCloud is a helpful tool, some of its advanced features are still under development."
"Qualys TotalCloud's increasing complexity, due to the development and deployment of multiple solutions, is making the GUI difficult to navigate."
"The downside is only in container security, but it has not been a long time since they introduced these models."
"With the growing integration of AI, I would like Qualys to enhance its service offerings to better accommodate AI-related risks."
"I sometimes have difficulty detecting or uninstalling certain versions of applications, which I have to do manually."
"Their customer support needs improvement."
"The integration could be better, especially with different types of solutions."
"The interface is really helpful for technical people, but it is not user-friendly."
"It has an uninviting interface."
"It is highly scalable, but there is a limitation that it is only available on Cisco devices."
"It is not so easy to use and configure. It needs a bunch of further resources to work, which is mainly the biggest downside of it. The deployment is huge."
"The entire interface could be improved; it's ugly and uninviting, and Tetration tends to be a lot more cumbersome and not very intuitive compared to the biggest competitor's modern-looking GUI."
"The product should be easy to use, but it is not. Comparing it to other products, it was very complex."
"A feature that I was looking for was emailed alerts and notifications so we'd get them right away."
"Agent features need to be improved. Sometimes, we are not able to get correct signals from the machines on which we have installed these agents."
"When you work with it, the only problem that we're struggling with is that we have 21 different subscriptions we're trying to apply security to. It's impossible to keep everything organized."
"Sometimes if you do not have the resources in-house, it can be difficult."
"There is no perfect product in the world and there are always features that can be added."
"The solution's portal is very easy to use, but there's one key component that is missing when it comes to managing policies. For example, if I've onboarded my server and I need to specify antivirus policies, there's no option to do that on the portal. I will have to go to Intune to deploy them. That is one main aspect that is missing and it's worrisome."
"The solution could improve by being more intuitive and easier to use requiring less technical knowledge."
"I recommend that they extend the scope for legacy infra assets."
"The remediation process could be improved."
 

Pricing and Cost Advice

"TotalCloud's price is about right where I would expect it to be."
"As a middle management member, I do not have direct pricing knowledge, but based on the knowledge from our meetings, its pricing is competitive."
"Qualys TotalCloud is expensive, but it offers a premier solution with no headaches."
"The cost is high, but it meets our organizational needs."
"It isn't cheap, but it's reasonable. It helps us to manage things with very few resources."
"While Qualys TotalCloud's pricing is currently acceptable, it is becoming increasingly expensive and may soon be considered overpriced."
"Qualys TotalCloud offers cost-effective licensing flexibility."
"Qualys TotalCloud offers good pricing that is affordable and competitive with the market. Our partnership also provides us with additional benefits."
"Regarding price, Cisco Secure Workload can be expensive if you don't have a budget. If you're not doing micro-segmentation, every extra security measure or enforcement you're putting on top of your existing environment will be an extra cost. It's not a cheap solution at all. But from my point of view, if you need to do micro-segmentation, this is one of the best tools I've seen for it. I can't compare that to Microsoft's solution because I haven't looked into it. I've looked into VMware and Cisco. Those are the only two that I know of. I didn't know that Microsoft could do micro-segmentation at all. Maybe they can, but I haven't heard anything about it."
"The price is outrageous. If you have money to throw at the product, then do it."
"Pricing depends on the scope of the application and the features. Larger installations save more."
"The price is based on how many computers you're going to install it on."
"The pricing is a bit higher than we anticipated."
"The cost for the hardware is around 300k."
"It is not cheap and pricing may limit scalability."
"It is bundled with our enterprise subscription, which makes it easy to go for it. It is available by default, and there is no extra cost for using the standard features."
"I rate Microsoft Defender a three out of ten for affordability. The price could be a little lower."
"The product's pricing policy is generally favorable."
"The solution is expensive, and I rate it a five to six out of ten."
"We are using the free version of the Azure Security Center."
"This is a worldwide service and depending on the country, there will be different prices."
"The pricing model for most plans is generally good, but the cost of the new Defender for Storage plan is high and should be revisited, as it could lead to disabling desirable security features due to cost."
"While we pay for any additional features, the pricing seems competitive, though I am not involved in the specific cost details."
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Top Industries

By visitors reading reviews
Manufacturing Company
18%
Financial Services Firm
14%
Construction Company
7%
Comms Service Provider
7%
Manufacturing Company
14%
Financial Services Firm
10%
Government
9%
Computer Software Company
8%
Financial Services Firm
12%
Computer Software Company
10%
Manufacturing Company
9%
Government
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise3
Large Enterprise29
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise3
Large Enterprise8
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise12
Large Enterprise49
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
Areas that need improvement in every solution include the remediation part. The remediation steps should be simple en...
What is your primary use case for Qualys TotalCloud?
Our use case involves the assets that we have under cloud, the assets exposed to the internet, and the internal appli...
What is your experience regarding pricing and costs for Cisco Secure Workload?
CloudStrike offers antivirus capabilities and firewall features for servers and VDI but lacks automatic policy discov...
What needs improvement with Cisco Secure Workload?
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration a...
What is your primary use case for Cisco Secure Workload?
When we onboarded Cisco Secure Workload, the usual use case was to discover internal application dependencies and cre...
How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening acros...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup costs, and licensing was that the license cost was the only consideration. Setup an...
What needs improvement with Microsoft Defender for Cloud?
To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an inges...
 

Also Known As

Qualys TotalCloud with FlexScan
Cisco Tetration
Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

Information Not Available
ADP, University of North Carolina Charlotte (UNCC)
Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Find out what your peers are saying about Cisco Secure Workload vs. Microsoft Defender for Cloud and other solutions. Updated: June 2026.
900,644 professionals have used our research since 2012.