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Cisco Secure Workload vs Microsoft Defender for Cloud comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Cloud Workload Protection Platforms (CWPP)
7th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
41
Ranking in other categories
Vulnerability Management (10th), Container Security (11th), Cloud Security Posture Management (CSPM) (7th), SaaS Security Posture Management (SSPM) (2nd), Cloud-Native Application Protection Platforms (CNAPP) (6th)
Cisco Secure Workload
Ranking in Cloud Workload Protection Platforms (CWPP)
18th
Average Rating
8.6
Reviews Sentiment
7.7
Number of Reviews
15
Ranking in other categories
Cloud and Data Center Security (7th), Microsegmentation Software (4th), Cisco Security Portfolio (7th)
Microsoft Defender for Cloud
Ranking in Cloud Workload Protection Platforms (CWPP)
1st
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
89
Ranking in other categories
Vulnerability Management (5th), Container Management (6th), Container Security (4th), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (4th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (3rd)
 

Mindshare comparison

As of August 2026, in the Cloud Workload Protection Platforms (CWPP) category, the mindshare of Qualys TotalCloud is 1.7%, up from 1.3% compared to the previous year. The mindshare of Cisco Secure Workload is 2.0%, down from 2.8% compared to the previous year. The mindshare of Microsoft Defender for Cloud is 11.7%, down from 13.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Cloud Workload Protection Platforms (CWPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Cloud11.7%
Qualys TotalCloud1.7%
Cisco Secure Workload2.0%
Other84.6%
Cloud Workload Protection Platforms (CWPP)
 

Featured Reviews

RO
IT Security Expert at Alior Bank S.A.
Unified risk scoring has improved our cloud visibility and simplifies remediation priorities
Qualys TotalCloud provides unified vulnerability and threat assessment across both IAS and SaaS. This solution provides a single prioritized view of risk, which helps reduce the work I would have to do. We are no longer based on CVSS; we are based on Qualys risk scoring, which is based on CVSS plus internal findings made by Qualys, and then assigns its own score. The TruRisk insight feature has found a small number of assets with high vulnerability scores, though I am cautious since some information is classified. Qualys TotalCloud has positively impacted our bank's performance, and we have definitely seen benefits after implementing this solution.
Raj Metkar - PeerSpot reviewer
Director, Head of Networks at MUFG, EMEA
Discover internal application dependencies and create a dependency map
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration allows Cisco Secure Workload to learn about our networks and network tags, providing valuable insights into vulnerabilities related to the operating system and various applications installed on our servers. Recently, Cisco announced a new product called HyperShield, an AI-based autonomous micro-segmentation solution. While Cisco has not stated that HyperShield will replace Cisco Secure Workload, it represents a natural evolution for the company. HyperShield features dynamic policy discovery and enforcement; however, once policies are enforced, they do not change until a discovery occurs, requiring a re-enforcement process. This new platform operates autonomously, minimizing the need for user or security engineer intervention. I would have expected Cisco to incorporate more automatic discovery and enforcement features within the existing Cisco Secure Workload product. Instead of enhancing the current product, they have introduced a new solution. Cisco plans to honor existing Tetration licenses, allowing users to transition to HyperShield without additional costs, reflecting the investment enterprises have already made. From Cisco’s perspective, this represents a natural progression in their product line. While the product name changes, it seems more of a rebranding effort. The enhancements are greater autonomy, improved discovery, and automatic enforcement, which are now being introduced in HyperShield. Cisco Secure Workload offers automatic policy enforcement but cannot adjust policies dynamically as the application needs to change. Having used the platform for the past five years, the recent announcement has been reassuring. Cisco has confirmed that our investment in the platform will not go to waste. They will honor our existing licenses, providing a natural migration path to the new solution without any disruption
RW
Head Of IT at Cirrus Response
Cloud security has cut investigation time and now reveals threats faster but needs simpler oversight
When deploying AI applications, my key security concerns with Microsoft Defender for Cloud are data loss, leakage of data, and guardrails around the actual AI, and I am hoping that this is going to help me put those guardrails in place and identify data exfiltration. Microsoft Defender for Cloud has not helped me manage and secure multi-cloud environments, as we are 100 percent Microsoft and have not really got it in any other environment at all. I am not yet using the unified AI-powered security feature offered by Microsoft Defender for Cloud, but that is coming. I am not yet using the integrated XDR feature of Microsoft Defender for Cloud, but that is coming. I am not yet utilizing the GenAI threat protection features of Microsoft Defender for Cloud. That is also coming and a lot of that will come from learning it here. I have enabled the agentless scanning in my cloud environment with Microsoft Defender for Cloud. Assessing the impact on my workload protection without needing to install agents with Microsoft Defender for Cloud makes it a lot easier, but it also identifies a lot more, which puts more load on me sometimes. I would advise another organization considering Microsoft Defender for Cloud that it is the most logical route to follow if their whole ecosystem is Microsoft. It is easy to implement and it is very self-explanatory when doing it, making sense to just follow the steps as it is too simple, really. I would rate this review a 7.5 out of 10.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"One of Qualys' best features is its categorization, which allows us to see the types of assets, their security postures, and the AI-powered version of the tool."
"The vulnerability management feature is the one I like the most because it provides a clear picture of all vulnerabilities."
"By integrating TotalCloud, we have significantly reduced vulnerabilities in our deployment pipeline."
"The most valuable feature of Qualys TotalCloud is the visibility it provides."
"The best features in Qualys TotalCloud include the total asset management of the cloud environment. It is very easy to export the report and see the vulnerabilities related to the cloud specifically."
"In my opinion, this is the best tool."
"Qualys TotalCloud has improved our security posture."
"The scalability is good as well. I would rate it ten out of ten."
"Scalability is its most valuable feature."
"The only use case I can see that makes sense is micro-segmentation. I think there are other use cases for it. The main purpose of the product is to do micro-segmentation by collecting IP. That could be done by installing an agent, and then you have all the communication coming in and out. You could also use some flow sensors installed in the network that receive a copy of the traffic and then report that back to the system."
"By using Tetration insight, we are able to get the latency on our level accounts and we can determine whatever the issue is with the application latency itself."
"Instead of proving that all the access control lists are in place and all the EPGs are correct, we can just point the auditor to a dashboard and point out that there aren't any escaped conversations. It saves an enormous, enormous amount of time."
"It's stable."
"Generally speaking, Cisco support is considered one of the best in the networking products and stack."
"The most valuable feature right now is to do with having visibility on the network — especially on our servers — and to be able to enforce some type of security measures."
"This product does everything that you need it to do and more and does a lot to provide visibility in a network environment, save time and money, and make the organization IT operate in a much more streamlined fashion."
"Microsoft Defender for Cloud has improved our security poster by at least 100 percent."
"The entire Defender Suite is tightly coupled, integrated, and collaborative."
"It alerts us to our vulnerabilities and ensures compliance by marking off a compliance tool checklist."
"Technical support is helpful."
"Our main use cases for Microsoft Defender for Cloud involve scanning PCs."
"The solution has also simplified management of endpoints and servers and gives us visibility in a single pane of glass."
"Using Security Center, you have a full view, at any given time, of what's deployed, and that is something that is very useful."
"It takes very little effort to integrate it, and it also gives very good visibility into what exactly is happening."
 

Cons

"I would like the ability to disable certain default built-in policies as they can be misleading when creating dashboards. That is the top one."
"Although TotalCloud is a helpful tool, some of its advanced features are still under development."
"The cost of Qualys TotalCloud is high and could be more competitive."
"The cloud licensing unit system is unclear, especially since "units" aren't well-defined."
"TotalCloud could improve the classification of vulnerabilities. Specifically, it could enhance the categorization of what aspects fall under patches resolved by OS or software updates and what pertains to configuration adjustments."
"Enhancing clarity regarding its compliance capabilities would be beneficial, as the current scope is limited in geographic coverage."
"Some major banks and insurance companies require an on-premises solution for comprehensive vulnerability management, which TotalCloud does not offer."
"The support is not up to the mark and seems to be overburdened."
"The problem is that we can only deploy the particular solution where we have the hardware with Cisco."
"Secure Workload is a little complicated to use, and the dashboard isn't intuitive, so it takes a while to learn how to use it."
"It has an uninviting interface."
"The emailed notifications are either hard to find or they are not available. Search capabilities can be improved."
"I would have expected Cisco to incorporate more automatic discovery and enforcement features within the existing Cisco Secure Workload product."
"Cisco Tetration needs more flags and system alerts that we should get with network capture."
"There is some overlap between Cisco Tetration and AppDynamics and there are few DC tools, it would be great to have a single pane of glass, rather than have to jump between different tools."
"The interface is really helpful for technical people, but it is not user-friendly."
"It's really hard to get ahold of Microsoft support. When you buy a product, with the M365 portal, you're given the option to chat with somebody, and normally you don't hear back immediately."
"The overview provides you with good information, but if you want more details, there is a lot more customization to do, which requires knowledge of the other supporting solutions."
"The customer service at Microsoft has room for improvement. The first line of support is not technically adept and often requires engaging higher-level technicians to resolve issues."
"From a compliance standpoint, they can include some more metrics and some specific compliances such as GDPR."
"I think that the documentation and implementation guides could be improved."
"Customer service and support from Microsoft are very poor. Even for high-severity cases, response or resolution time can extend to three or four weeks."
"So, Azure Security Center fell short from the regulatory compliance point of view, and we had to use one more product."
"It's hard to reach someone who understands my problems. I haven't had many issues, so I haven't called them."
 

Pricing and Cost Advice

"The pricing for TotalCloud is attractive and competitive in the market. Given the features, especially the dashboard, I have no concerns regarding pricing."
"Although Qualys TotalCloud is relatively expensive due to its unique automation features, its cost-effectiveness is rated an eight out of ten, with ten being the most costly."
"The pricing is comparable. It is built into our other product, so I cannot piecemeal it. It is a part of our subscription."
"I am not sure about the pricing. From what I understand, it is a bit on the higher side, but I do not have the exact numbers."
"It isn't cheap, but it's reasonable. It helps us to manage things with very few resources."
"TotalCloud's price is about right where I would expect it to be."
"Qualys TotalCloud offers cost-effective licensing flexibility."
"Qualys TotalCloud is expensive."
"Pricing depends on the scope of the application and the features. Larger installations save more."
"Regarding price, Cisco Secure Workload can be expensive if you don't have a budget. If you're not doing micro-segmentation, every extra security measure or enforcement you're putting on top of your existing environment will be an extra cost. It's not a cheap solution at all. But from my point of view, if you need to do micro-segmentation, this is one of the best tools I've seen for it. I can't compare that to Microsoft's solution because I haven't looked into it. I've looked into VMware and Cisco. Those are the only two that I know of. I didn't know that Microsoft could do micro-segmentation at all. Maybe they can, but I haven't heard anything about it."
"The pricing is a bit higher than we anticipated."
"The price is outrageous. If you have money to throw at the product, then do it."
"The price is based on how many computers you're going to install it on."
"It is not cheap and pricing may limit scalability."
"The cost for the hardware is around 300k."
"They have a free version, but the license for this one isn't too high. It's free to start with, and you're charged for using it beyond 30 days. Some other pieces of Defender are charged based on usage, so you will be charged more for a high volume of transactions. I believe Defender for Cloud is a daily charge based on Azure's App Service Pricing."
"Although I am outside of the discussion on budget and costing, I can say that the importance of security provided by this solution is of such importance that whatever the cost is, it is not a factor."
"Pricing is a consideration, but we strive to keep costs low by enabling only necessary services."
"The pricing model for most plans is generally good, but the cost of the new Defender for Storage plan is high and should be revisited, as it could lead to disabling desirable security features due to cost."
"Our clients complain about the cost of Microsoft Defender for Cloud."
"The licensing cost per server is $15 per month."
"I rate Microsoft Defender a three out of ten for affordability. The price could be a little lower."
"Currently, Microsoft offers only one plan at the enterprise level which is $15 per machine."
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Top Industries

By visitors reading reviews
Manufacturing Company
13%
Outsourcing Company
12%
Comms Service Provider
10%
Financial Services Firm
10%
Manufacturing Company
14%
Financial Services Firm
9%
Government
9%
Computer Software Company
7%
Financial Services Firm
12%
Computer Software Company
10%
Manufacturing Company
8%
Government
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business11
Midsize Enterprise5
Large Enterprise30
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise3
Large Enterprise8
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise12
Large Enterprise49
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
To be totally honest, I do not have any best features because I have had a bad experience using this tool, especially...
What is your primary use case for Qualys TotalCloud?
My main use case for Qualys TotalCloud is vulnerability management and exposure management. I use this tool to evalua...
What is your experience regarding pricing and costs for Cisco Secure Workload?
CloudStrike offers antivirus capabilities and firewall features for servers and VDI but lacks automatic policy discov...
What needs improvement with Cisco Secure Workload?
We actively seek improvements in integrating the Infoblox DDI platform with Cisco Secure Workload. This integration a...
What is your primary use case for Cisco Secure Workload?
When we onboarded Cisco Secure Workload, the usual use case was to discover internal application dependencies and cre...
How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening acros...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup costs, and licensing was that the license cost was the only consideration. Setup an...
What needs improvement with Microsoft Defender for Cloud?
To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an inges...
 

Also Known As

Qualys TotalCloud with FlexScan
Cisco Tetration
Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

Information Not Available
ADP, University of North Carolina Charlotte (UNCC)
Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Find out what your peers are saying about Cisco Secure Workload vs. Microsoft Defender for Cloud and other solutions. Updated: June 2026.
908,800 professionals have used our research since 2012.