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CylanceENDPOINT vs Microsoft Defender for Endpoint comparison

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Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Detection and Response (EDR) (5th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
CylanceENDPOINT
Ranking in Endpoint Protection Platform (EPP)
63rd
Average Rating
8.0
Reviews Sentiment
7.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
1st
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Advanced Threat Protection (ATP) (4th), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
 

Mindshare comparison

As of September 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.8%, up from 3.8% compared to the previous year. The mindshare of CylanceENDPOINT is 0.3%, up from 0.0% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 6.5%, down from 10.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.5%
Cortex XDR by Palo Alto Networks3.8%
CylanceENDPOINT0.3%
Other89.4%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Raphael Haroun  Ikyagh - PeerSpot reviewer
Network Administrator at Letshego
Stable, good for malware detection and prevention
I use it for general endpoint protection and the usual stuff like malware detection and prevention It secures my environment.  One thing that could be easier is initiating scans. If I want to scan an extra drive, it should be more straightforward. It's a bit clunky. I have been using it for…
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Technical support is the best in class, in my opinion, because they have invested heavily in research and development."
"It's a perfect solution. It integrates well into the environment."
"We think that this product will help us grow, as it meets our needs currently and we can grow with it over time."
"Being a cloud solution it is very flexible in serving internal and external connections and a broad range of devices."
"Monitoring is most valuable."
"Its interface and pricing are most valuable, and it is better than other vendors in terms of security."
"We use it for malicious connections from malicious websites, to identify payloads that might be inside the traffic, to identify malicious processes or bugs that are running on the network, and any activities that tend to lead to data infiltration."
"When the pandemic started, Palo Alto came up with many solutions, which helped with the quick shift from on-premises to the cloud."
"It secures my environment."
"It's a Microsoft product; it's easier to deploy this product than other options."
"A few years ago, when I was using a different product, I was affected by a virus that destroyed everything. Since using Microsoft Defender, I have not had this kind of problem."
"We are a Microsoft shop, and Defender is a Microsoft solution that provides some security at a reasonable cost."
"The solution provides good security features, and the key valuable feature for me is that you can view it in the central console."
"Windows is a great tool that I have used; it has helped my organisation in achieving what it does daily and protected our data in a great way."
"It definitely improves the organization in terms of security and productivity."
"Technical support is good."
"The best feature is the fact that for certain mobiles you can control your corporate profiles versus your personal profiles. That is amazingly important. Apple just supported the separation of corporate and personal profiles, whereas Android has been doing that for quite some time... Because Android supports that, if an Android phone is lost or stolen, I can wipe out all the corporate-related information from that phone and not touch the personal side. I can separate the apps and I can separate the ability to cut and paste between apps."
 

Cons

"In reporting they should have a customizable dashboard due to the fact that C-level people don't like reporting to the IT department. They prefer to have a real-time dashboard. That kind of dashboard needs to have various customizations."
"In an upcoming release, the solution could improve by proving hard disk encryption. If it could support this it would be a complete solution."
"Dashboards do not allow everyone to see what's happening."
"On the pricing aspect, Cortex XDR by Palo Alto Networks needs to have a more reasonable rate, particularly for customers in Sri Lanka and Asian countries."
"I have seen lagging with Cortex XDR by Palo Alto Networks. There was one time when we faced a threat actor trying to gain access to our system. When our team utilized the tool, we were all on the same dashboard and we faced a lag issue at that time of around five minutes, which was quite significant."
"In general, the price could be more competitive."
"I am facing issues with customer support for Cortex XDR by Palo Alto Networks, so I am not satisfied with customer support."
"The solution lacks real-time, on-demand antivirus."
"One thing that could be easier is initiating scans."
"There is some functionality that is not quite there yet."
"My main issue with the tool is that there are too many menus."
"Sometimes, there are difficulties in downloading a file considered as malicious."
"I think the overall portal of Microsoft Defender for Endpoint could be improved; sometimes there's moving around to different spots and it's a little hard to navigate, so getting used to that was perhaps the biggest hurdle."
"Defender's cloud integration could be improved."
"Microsoft Defender for Endpoint is a basic endpoint protection solution. If you do not combine it with another solution then you will leave yourself open to vulnerabilities."
"Windows Firewall is integrated with Windows Defender. Over the last few days, I have had a problem with defining a wildcard on Windows Firewall."
"Additional security would be beneficial."
 

Pricing and Cost Advice

"The price of the solution could be reduced. I have customers that have voiced that the solution is good for the value but if I want to sell more of the solution the price reduction would help."
"The tool's price is moderate."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"This is an expensive solution."
"Cortex XDR’s pricing is very reasonable."
"It's about $55 per license on a yearly basis."
"The solution has one subscription for endpoint protection and one subscription for detection and response. The two licenses combined give you the BRO version."
"The pricing is a little bit on the expensive side."
Information not available
"Currently, for us, Windows Defender is free with the purchase of Windows Server. Pricing is an important point for us when we are looking at the competitors of this solution. If we choose to go with another vendor, we will have to pay some license fees."
"Pricing for Microsoft Defender for Endpoint is competitive. Out of the bundle, you will get a lot of security, if I talk about Microsoft E5, for example, and get a lot of benefits. If the customer goes and purchases a different solution, it will cost more, so pricing for Microsoft Defender for Endpoint is quite reasonable at the moment. There isn't any challenge in terms of pricing, for example, I didn't see a customer who pulled back because of the price. Some prices could be negotiable, and sometimes, as a sales point, the two become negotiable, but they don't bill one and pull back because of the pricing. If you have an E5 license, you get everything."
"The solution comes as part of Microsoft Windows."
"This product is included in the pricing for Windows."
"The nice thing about Defender and Sentinel is that the cost is based on the data logs that you ingest from the Defender endpoints and data connectors. I don't have to buy a 25- or 50- or 1,000-user or enterprise license. I can buy one license at a time."
"Most people don't realize M365/E5 licenses are an amazing deal. They think "Oh, it's expensive," and I'll ask, "Compared to what?" If you don't have it you will have to buy licenses for multiple products to fill the same security space that you would have gotten with the Microsoft product. Go figure out how much it costs you per product, per user, and then come back and tell me how things add up financially."
"It isn't cheap, but it's reasonable and fair."
"There is an annual license required."
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Financial Services Firm
9%
No data available
Manufacturing Company
10%
Financial Services Firm
9%
Comms Service Provider
8%
Computer Software Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
No data available
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise97
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
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Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior sol...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never pu...
What is your experience regarding pricing and costs for Microsoft Defender for Endpoint?
We have been discussing pricing, setup cost, and licensing, and we are currently on an E3. We are discussing going to...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
No data available
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
 

Interactive Demo

Demo not available
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Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Information Not Available
Petrofrac, Metro CSG, Christus Health
Find out what your peers are saying about Microsoft, SentinelOne, CrowdStrike and others in Endpoint Protection Platform (EPP). Updated: September 2026.
913,683 professionals have used our research since 2012.