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CylanceENDPOINT vs Microsoft Defender for Endpoint comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Endpoint Protection Platform (EPP)
4th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
115
Ranking in other categories
Endpoint Detection and Response (EDR) (5th), Extended Detection and Response (XDR) (4th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
CylanceENDPOINT
Ranking in Endpoint Protection Platform (EPP)
63rd
Average Rating
8.0
Reviews Sentiment
7.7
Number of Reviews
1
Ranking in other categories
No ranking in other categories
Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
1st
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Advanced Threat Protection (ATP) (5th), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
 

Mindshare comparison

As of August 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Cortex XDR by Palo Alto Networks is 3.9%, up from 3.7% compared to the previous year. The mindshare of CylanceENDPOINT is 0.3%, up from 0.0% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 6.7%, down from 10.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint6.7%
Cortex XDR by Palo Alto Networks3.9%
CylanceENDPOINT0.3%
Other89.1%
Endpoint Protection Platform (EPP)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
Raphael Haroun  Ikyagh - PeerSpot reviewer
Network Administrator at Letshego
Stable, good for malware detection and prevention
I use it for general endpoint protection and the usual stuff like malware detection and prevention It secures my environment.  One thing that could be easier is initiating scans. If I want to scan an extra drive, it should be more straightforward. It's a bit clunky. I have been using it for…
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The product's initial setup phase is very easy."
"The anti-exploit is impenetrable."
"The stability of this product is very good."
"The product's most valuable features are massive user and feature intelligence exploit detection."
"I like the centralized console and the predictive analysis it does of malware. It is very stable and also scalable."
"The best feature of Cortex XDR by Palo Alto Networks is that it collects logs from different sections such as the endpoint, the network, and the cloud, making it easy to investigate alerts, collect some of the investigation packages related to the infected machines, and provide live response."
"From the Palo Alto side, whatever they buy, they integrate that really well into their integration suite, and that makes a massive difference."
"Cortex XDR alerts us on the dashboard when there's a threat, which allows us to restrict that user and helps secure our infrastructure."
"It secures my environment."
"The primary advantage is that you don't need to install it, because it's included in the Windows 10 delivery and is integrated as part of the Microsoft 365 suite."
"The antivirus features are very useful."
"We are still navigating through it, and it has been working very well."
"Defender is a part of Windows; you just need to enable it. There is no need to install anything."
"The most valuable feature is that we can use the solution right out of the box without too much configuration."
"It shows us the risky sign-ins, and if a user's password has been compromised."
"Microsoft Defender for Endpoint's threat intelligence has helped us prepare for potential threats before they hit and take proactive steps."
"File protection is the most valuable feature. Antivirus security on the Level OS, Microsoft Defender, and Microsoft Guard for 2019."
 

Cons

"The GUI could be improved."
"The main issue I could point out is the offline agents and the way that it is missing."
"When it comes to malware files, it should be a little quick because, at times, it would give a wrong result in the sense of what it might be on malware, even if it still might be a normal one."
"The encryption is not up to the mark."
"I have seen lagging with Cortex XDR by Palo Alto Networks. There was one time when we faced a threat actor trying to gain access to our system. When our team utilized the tool, we were all on the same dashboard and we faced a lag issue at that time of around five minutes, which was quite significant."
"They've been having some issues with updating their endpoint agents, and it has been quite frustrating."
"While using Cortex, I noticed some aspects that could be improved, such as increasing the synchronization speed between XDR and Xnor."
"In reporting they should have a customizable dashboard due to the fact that C-level people don't like reporting to the IT department. They prefer to have a real-time dashboard. That kind of dashboard needs to have various customizations."
"One thing that could be easier is initiating scans."
"The technical from Microsoft could be better. It is not as good as other solutions."
"Something that is unique to Microsoft is its licensing model. When you go out and you buy McAfee or Symantec, you know what you're getting out of the box, but with Microsoft, often, when you're looking to achieve a certain set of capabilities, those capabilities are spread across different products. You might try to do something you could do with CrowdStrike, but then find out that you also need to purchase Microsoft Defender for Identity or Microsoft Defender for Azure. You realize that when they talk about what they can offer within the Microsoft platform, it's really the suite of investments. So, sometimes, you may find yourself buying Defender for Endpoint thinking that it matches CrowdStrike, but then you find that Microsoft really needs to sell you something else. One plus one will equal three, but when you have a very concise platform, such as CrowdStrike, you know what you're going to get."
"Notifications are always popping up — I hate that."
"The biggest issue I had with Microsoft Defender for Endpoint was the antivirus and ransomware. I wanted central visibility over all the machines that we operate."
"There are still some things where I think they don't quite match up or are a bit hard to find or understand."
"We have had reports where users experience slowness on their PCs when files are being scanned regarding the stability and reliability of Microsoft Defender for Endpoint."
"This solution is not secure, which is why I have moved to Linux."
"The time it takes to restore the application could be improved. It has a lot of dependencies. It's not like the Microsoft security that comes with the OS. Updating through the command prompt, most of the time, it takes some time to download some of these dependencies."
 

Pricing and Cost Advice

"Our license will require renewal in August, after which the maintenance will continue as usual."
"The pricing seems fair, and I do like the licensing model. You use wherever they are, and it is elastic."
"It's the most expensive solution, but features-wise, it's quite strong. It's very good for protection, so the results are very good in the case of protection. I would rate it a two out of ten in terms of pricing."
"The price was fine."
"The solution is expensive. It's pricing is on a yearly-basis."
"I am using the Community edition."
"Cortex XDR's pricing is ok."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
Information not available
"The solution is free."
"We have a bundle where the price includes all Microsoft products."
"When compared with other vendors, the pricing is very high."
"Everybody would like to see a lower price on everything. The Slovenian market is basically an SME market with clients having up to 100 seat licenses, comprising 90% of the company. They're very price sensitive. So, the price could be cheaper."
"We pay a yearly license for Microsoft Defender. We also have a support contract with them."
"Microsoft has different plans for buying this product. The price depends on the configuration of the full set of products that you buy and on the licensing program in your contract."
"The nice thing about Defender and Sentinel is that the cost is based on the data logs that you ingest from the Defender endpoints and data connectors. I don't have to buy a 25- or 50- or 1,000-user or enterprise license. I can buy one license at a time."
"It is built into Windows 10. If our clients are using Microsoft Defender, the cost goes away for them."
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Top Industries

By visitors reading reviews
Construction Company
13%
Financial Services Firm
10%
Comms Service Provider
10%
Manufacturing Company
10%
No data available
Manufacturing Company
10%
Financial Services Firm
9%
Computer Software Company
8%
Comms Service Provider
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise21
Large Enterprise54
No data available
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
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Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior sol...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never pu...
What is your experience regarding pricing and costs for Microsoft Defender for Endpoint?
We have been discussing pricing, setup cost, and licensing, and we are currently on an E3. We are discussing going to...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
No data available
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
 

Interactive Demo

Demo not available
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Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Information Not Available
Petrofrac, Metro CSG, Christus Health
Find out what your peers are saying about Microsoft, SentinelOne, CrowdStrike and others in Endpoint Protection Platform (EPP). Updated: July 2026.
908,800 professionals have used our research since 2012.