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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
3rd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
210
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of January 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 6.4%, down from 7.7% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.9%, up from 1.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Endpoint6.4%
Trellix Advanced Threat Defense1.9%
Other91.7%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Microsoft Defender for Endpoint is beneficial because we are using Microsoft Windows and all the core solutions are made by Microsoft, such as the authentic platform, operating system, and antivirus protection. It is a heterogeneous environment. We had to use third-party solutions before and update everything separately. For example, the policy for antivirus. With Microsoft Defender for Endpoint, when Microsoft Windows receives updates it will update with it. This is one main advantage of this solution."
"We can run the virus scan across our entire environment."
"Defender is stable. The performance is good."
"It is easy to install and use requiring little maintenance but applying updates."
"Defender for Endpoint has one dashboard with security-related information, vulnerability-related information, and basic recommendations from Microsoft, all in different tabs. That's helpful because if we want to fix only the recommended ones, we can go fix all of them..."
"The most valuable aspect lies in its automation capabilities, particularly within security automation."
"Its threat intelligence feature is beneficial. This solution smoothly integrates with SIEM."
"Microsoft Defender for Endpoint's most valuable feature is its ease of use."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"It is very scalable."
"I recommend this solution because of its ease of use."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"The most valuable features are the administration console and its detection and response module."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"Provides good exfiltration, and is an all-in-one product."
"It is stable and reliable."
 

Cons

"I would like Microsoft to have some kind of direct integration for USB controls. They have GPO and other controls to control the access of the USB drives on devices, but if there is something that can be directly implemented into the portal, it would be good. There should be a way to control via a cloud portal or something like that in a dynamic way. USB control for data exfiltration would be a good feature to implement. Currently, there are ways to do it, but it involves too many different things. You have to implement it via GPOs and other stuff, and then you move or copy those big files via Defender ATP. If there is a simple way of implementing those features, it would be great."
"The user interface could use some improvement."
"This solution needs to move beyond relying on virus definitions alone and protect the system using behavioral analysis of the processes that are running."
"Microsoft Defender for Endpoint is secure but when it comes to security all solutions could improve security."
"There is a lot of information to take in, and the portals tend to change quickly due to the fast-paced nature of the industry."
"Microsoft support could be more knowledgeable."
"The profiling method currently in use is not very user-friendly and has ample scope for improvement."
"We encountered some issues when we were trying to enable automatic updates from our group policy."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"We'd like them to be better at dealing with script threats."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"Lacks remote capabilities not dependent on the internet."
"This solution needs to be made "cloud ready"."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
 

Pricing and Cost Advice

"You need a license to use this solution."
"Pricing for Microsoft Defender for Endpoint is competitive. Out of the bundle, you will get a lot of security, if I talk about Microsoft E5, for example, and get a lot of benefits. If the customer goes and purchases a different solution, it will cost more, so pricing for Microsoft Defender for Endpoint is quite reasonable at the moment. There isn't any challenge in terms of pricing, for example, I didn't see a customer who pulled back because of the price. Some prices could be negotiable, and sometimes, as a sales point, the two become negotiable, but they don't bill one and pull back because of the pricing. If you have an E5 license, you get everything."
"The E5 license is the one that I recommend because it comes with Cloud App Security, which is a good thing to have on top of Microsoft Defender."
"The price is fair for the features Microsoft delivers. If you want tailor-made features, you have to mix different licenses. It isn't straightforward."
"They are now doing it on an endpoint basis. It is based on the number of endpoints, which is good."
"You just pay Windows 10 prices, then you have antivirus software. As a price comparison, Defender's costs are very low."
"We have seen ROI. Most of the other competing alternatives will cost up to around $30 per user device. We average 400 devices. Therefore, the amount that we save each year is 400 times $30."
"It is free. It is included in Windows 10."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
No data available
Government
15%
Comms Service Provider
13%
Performing Arts
11%
University
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business80
Midsize Enterprise40
Large Enterprise92
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: December 2025.
881,082 professionals have used our research since 2012.