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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
4th
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of September 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.6%, down from 7.8% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.6%
Trellix Advanced Threat Defense2.1%
Other92.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The whole bundle of the product, which is similar to other Microsoft products, is valuable. Ten years ago, you had third-party stuff for different things. You had one solution for email archiving and another third-party one for something else. Nowadays, Microsoft Office covers all the stuff that was formerly covered by third-party solutions. It is the same with antivirus. The functionality is just basic. You have the scanning, and then you also have a kind of cloud-based protection and reporting about your environment. With Microsoft Security Center, you have a complete overview of your environment. You know the software inventory, and you have security recommendations. You can not only see that the antivirus is up to date; you can also see where are the vulnerabilities in your system. Microsoft Security Center tells you where you have old, deprecated software and what kind of CVEs are addressed. It's really cool stuff."
"The scalability is amazing; using Azure, the sky is the limit."
"The most important feature is the way it monitors the threats and blocks them. About 10 days ago, we were implementing SOC for a particular client. The SOC was not yet implemented, but they had Microsoft Defender. That organization was hit by some ransomware, but the hacker could not succeed. Because of the EDR, the hacker could not install the hacking tools. They were trying to do that, but Microsoft Defender completely blocked that. The hacker could log into the system, but they could not install anything."
"Technical support is good."
"We are able to productively integrate with existing on-prem, hybrid, or cloud applications."
"It depends on the licensing. Most of the customers have got at least a 365 E3 license, and they can use most of the features of Windows 10 Defender. So, anyone who has got an enterprise license can start using those features. Some of the customers have got E5 licenses, and they can use all advanced features. Customers with E5 licenses use the advanced site protection (ATP) features and web content filtering without going via a proxy, which gives the benefit of replacing the proxy. They can get the benefit of MCAS and integration with Intune and the endpoint manager. It is a kind of single platform for all 365 technologies. It helps customers in managing everything through a unified portal."
"We have liked the fact that it comes with Microsoft Windows 10 and it is constantly updated with all new virus definitions. It is also updated with new security features on a regular basis."
"Defender for Endpoint has significantly reduced our SOC team's workload by automating threat detection and response, allowing them to focus on other critical projects."
"The most valuable features are the administration console and its detection and response module."
"It was easy to set up initially."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
"Provides good exfiltration, and is an all-in-one product."
"I recommend this solution because of its ease of use."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"The product is expensive, but it is better than the rest of them in the industry."
 

Cons

"Microsoft Defender for Endpoint does not provide much flexibility in terms of threats."
"The detection of viruses could be a little bit better."
"The major area for improvement is the integration with a managed service provider."
"If there were more template queries in the library, that would make it much easier. They could have basic things, like, "Where's the IP for this user?" or, "What file was downloaded from this user?" If there were more of those basic queries that would help."
"I would like MDE to have the ability to isolate a certain amount of time on the timeline."
"It can get a bit laggy sometimes."
"With the XDR dashboard, when you're doing an investigation and you're drilling down to obtain further details it tends to open many different tabs that take you away from your main tabs. You can end up having 10 tabs open for one investigation. This is another area for improvement because you can end up getting lost in the multiple tabs. Therefore, the central console can be improved so that it does not take you to several different pages for each investigation."
"They're in the process of pulling more things together. They can continue with the integrations and provide a better way of seeing the impact of security changes, especially on the endpoint side. Before we actually flip the switch, we should be able to see the impact of security changes on the business or business applications. It would prevent breaking any business applications."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"The support on their side is not readily available. It takes a while."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"We'd like them to be better at dealing with script threats."
"This solution needs to be made "cloud ready"."
 

Pricing and Cost Advice

"When compared with other vendors, the pricing is very high."
"The solutions price could be cheaper."
"The solution comes free with Microsoft Windows 10."
"Microsoft Defender for Endpoint is an expensive solution."
"Licensing fees are paid annually through a partner."
"The solution is free with Windows."
"Microsoft Defender ATP is expensive."
"Microsoft Defender for Endpoint is more affordable compared to some other endpoint solutions."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Top Industries

By visitors reading reviews
Manufacturing Company
10%
Financial Services Firm
9%
Comms Service Provider
8%
Computer Software Company
8%
Construction Company
16%
Outsourcing Company
14%
Comms Service Provider
11%
Financial Services Firm
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise97
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: September 2026.
913,924 professionals have used our research since 2012.