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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
8.2
Reviews Sentiment
6.9
Number of Reviews
213
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of March 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.5%, down from 7.8% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.5%
Trellix Advanced Threat Defense2.1%
Other92.4%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution integrates very well with Windows applications and Microsoft endpoint products."
"Microsoft Defender for Endpoint has changed significantly for the better."
"Stable endpoint manager, antivirus, and antimalware, with fast technical support and a straightforward setup."
"Its threat intelligence feature is beneficial. This solution smoothly integrates with SIEM."
"It comes included with the Windows license."
"It's free. There is no additional cost. It's part of Windows."
"It's a very complete application. I have all the controls in one site. I can track emails, attacks, and threats, and I can research information. I really like this configuration because I have all the information in place."
"Defender for Endpoint is a robust solution that works well out-of-the-box."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"I recommend this solution because of its ease of use."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"Provides good exfiltration, and is an all-in-one product."
"The most valuable features are the administration console and its detection and response module."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"The product is expensive, but it is better than the rest of them in the industry."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
 

Cons

"Defender could be more secure and stable."
"Other vendors provide a lot of customization when it comes to integration, which every big organization requires. No big organization depends on one particular tool. Defender lacks that at this point."
"They should bring back the feature of a dedicated proxy device for communication to the cloud. As of now, all the agents are required to send the logs directly to the cloud. There should be a solution where you can put a proxy and all the logs are consolidated, like a forwarder."
"Threat intelligence has the potential for improvement, particularly by integrating more sources."
"The interface isn't necessarily intuitive to a nontechnical person. You can get stuck in the little endpoint security portal. Sometimes, if you uninstall a competitive product, the end user doesn't always know if it's running or if they're protected even though it's silently running. There could be a notification, widget, or something that's resident on the screen for at least a bit, especially if you're doing remote support. You want to talk them through it, but sometimes, we're not allowed to look at the PCs we support."
"There are alternative solutions that offer a greater range of dashboard insights when compared to Microsoft Defender for Endpoint."
"When you get the right person that knows what you are asking the first time, it is excellent. However, when you get someone who may be new or just switched into that role, it can be less effective."
"The system can always be simplified and have a better integration check."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"Lacks remote capabilities not dependent on the internet."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"We'd like them to be better at dealing with script threats."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The support on their side is not readily available. It takes a while."
 

Pricing and Cost Advice

"As we operate in the educational sector, we are eligible for an educational discount."
"Pricing for Microsoft Defender for Endpoint is competitive. Out of the bundle, you will get a lot of security, if I talk about Microsoft E5, for example, and get a lot of benefits. If the customer goes and purchases a different solution, it will cost more, so pricing for Microsoft Defender for Endpoint is quite reasonable at the moment. There isn't any challenge in terms of pricing, for example, I didn't see a customer who pulled back because of the price. Some prices could be negotiable, and sometimes, as a sales point, the two become negotiable, but they don't bill one and pull back because of the pricing. If you have an E5 license, you get everything."
"The price is higher than others because it is doing more than what the others are doing."
"Microsoft Defender for Endpoint is an expensive solution."
"There is no licensing fee."
"Most people don't realize M365/E5 licenses are an amazing deal. They think "Oh, it's expensive," and I'll ask, "Compared to what?" If you don't have it you will have to buy licenses for multiple products to fill the same security space that you would have gotten with the Microsoft product. Go figure out how much it costs you per product, per user, and then come back and tell me how things add up financially."
"The solution is included with Microsoft Windows."
"Licensing models of Microsoft are renowned for being complex. We just purchased the whole E5 stack. With E5 licenses for users, we get access to a bunch of features that are not just related to security. I would rate them a three out of five in terms of pricing."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Computer Software Company
10%
Manufacturing Company
9%
Financial Services Firm
8%
Government
8%
Comms Service Provider
14%
Outsourcing Company
12%
Performing Arts
12%
University
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business81
Midsize Enterprise40
Large Enterprise95
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: March 2026.
884,933 professionals have used our research since 2012.