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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
4th
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
214
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
23rd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of May 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.7%, down from 7.7% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.7%
Trellix Advanced Threat Defense2.1%
Other92.2%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"For the end user it's good to know that everything is safe and well protected."
"Microsoft Defender for Endpoint has significantly impacted our security posture."
"The solution can scale as needed."
"This a very good product because every time there is an update it corrects any issues."
"It is very stable, highly recommended, free with the purchase of Windows Server, and it is doing its job for Microsoft Windows Server as a good product."
"Defender for Endpoint has significantly improved our security posture."
"Microsoft Defender for Endpoint has helped free up our SOC team to work on other projects or tasks."
"Overall, our security posture looks much better and our attack surfaces are limited."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
"The product is expensive, but it is better than the rest of them in the industry."
"The most valuable features are the administration console and its detection and response module."
"It is very scalable."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"The most valuable features are the administration console and its detection and response module."
 

Cons

"I would like to see improvements made to how it secures activities on web pages."
"In India at least, it seems to be a bit more expensive than other options."
"I would like to see better integration with their other security products to give better visibility from a higher level."
"I would appreciate agentic protection as an additional feature in the next release to protect the agents that the business creates."
"Sometimes, there are different skews. In a basic skew, they should have basic log analysis without the need to integrate with any third-party or SIEM solutions, like Sentinel."
"I would like to have additional features such as DNS lookup, which would help for detecting malicious sites."
"Integrating this with third-party systems has some complexity involved."
"I would just like them to have more consistency, and that's a comment that's across the board with Microsoft. They change things a lot."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The support on their side is not readily available. It takes a while."
"We'd like them to be better at dealing with script threats."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"This product does the job, but it is not flexible enough to do new environments yet."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"We'd like them to be better at dealing with script threats."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
 

Pricing and Cost Advice

"It came with Windows."
"The solution comes as a part of Windows 10 and it is covered under its license."
"It is free. It is included in Windows 10."
"The solution is free and comes with Windows."
"The solution is free with Windows."
"If we are acquiring everything in a single place, the front end becomes cost-effective."
"The licensing costs for Microsoft Defender for Endpoint are reasonable."
"When customers haven't deployed the solution and don't have licenses, it can be expensive to start from scratch."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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893,311 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Computer Software Company
9%
Financial Services Firm
9%
Manufacturing Company
9%
Government
8%
Construction Company
16%
Comms Service Provider
12%
Outsourcing Company
11%
Financial Services Firm
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise44
Large Enterprise95
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: April 2026.
893,311 professionals have used our research since 2012.