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Microsoft Defender for Endpoint vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
212
Ranking in other categories
Endpoint Protection Platform (EPP) (1st), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (3rd)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of August 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Endpoint is 5.8%, down from 7.7% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.9%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Endpoint5.8%
Trellix Advanced Threat Defense1.9%
Other92.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"DFE organizational security posture has been a positive experience. We're a Microsoft house. It works. Once it's deployed and once it's configured, it works and our clients tend to be happy with it. I haven't really experienced anyone who has been so unsatisfied with the platform that they wanted to go a couple of different directions, that has never happened to me."
"Automatic scanning and cleaning of viruses is the best and most valuable feature helping this tool to thrive. If any viruses are found, they are cleaned automatically."
"We had some problem and, after four hours, we had new signatures for the environment by our customers for more than a thousand clients so that we can protect and improve the new setup."
"We can run the virus scan across our entire environment."
"It's a very complete application. I have all the controls in one site. I can track emails, attacks, and threats, and I can research information. I really like this configuration because I have all the information in place."
"Technical support is good."
"The main thing I like about Microsoft Defender for Endpoint is that you can integrate it with or deploy it with Intune, so it's really easy to deploy without needing to bring in any third-party solution."
"It's free because it comes with Windows."
"I recommend this solution because of its ease of use."
"The product is expensive, but it is better than the rest of them in the industry."
"This solution is very easy to use and requires little to no training."
"It is stable and reliable."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"It is very scalable."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
 

Cons

"Microsoft Defender in the basic form is not very useful for managing the security environment. The free version is not capable of covering the needs of centralized management, EDR, and behavioral analysis. If you don't have the commercial version, you can't have centralized management and set up the policies and other things. Each client is a standalone installation, which is not useful for security in an enterprise model."
"Our team's knowledge of the solution needs to be improved, and Microsoft could do a better job conveying the necessary information to users. We could proactively use the tool more and explore capabilities we are not yet utilizing."
"It should support non-Windows products better. Microsoft is now one of the leading vendors in the security area. So, they should be product-independent."
"Another concern is ransomware, whether people can penetrate and encrypt my data or steal my credit card/banking information."
"Sometimes it's complicated. It's not intuitive in terms of installation and deployment."
"Features like device inventory continue to lack essential workstation drill-downs showing the entire device information with the least effort."
"Microsoft Defender for Endpoint could provide us with a more holistic approach, such as collaboration. They can provide us with an environment from where we can manage all the endpoints from one central location, such as overall management."
"Their support could be faster through the phone. The support through chat is very unuseful; it takes a lot of time and effort and does not help in any way."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"Lacks remote capabilities not dependent on the internet."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"We'd like them to be better at dealing with script threats."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The support on their side is not readily available. It takes a while."
 

Pricing and Cost Advice

"This is an expensive product and licensing for all Microsoft products is a big issue."
"You do not need to pay any additional costs for antivirus and anti-malware solutions for endpoint protection."
"The normal, standalone model, is not expensive, but the enterprise model that includes the bundle with email and some web protection, is a bit more expensive."
"Compared to ESET, the pricing for Microsoft Defender for Endpoint is on the higher side."
"The solution is included with Microsoft Windows."
"Pricing for Microsoft Defender for Endpoint is competitive. Out of the bundle, you will get a lot of security, if I talk about Microsoft E5, for example, and get a lot of benefits. If the customer goes and purchases a different solution, it will cost more, so pricing for Microsoft Defender for Endpoint is quite reasonable at the moment. There isn't any challenge in terms of pricing, for example, I didn't see a customer who pulled back because of the price. Some prices could be negotiable, and sometimes, as a sales point, the two become negotiable, but they don't bill one and pull back because of the pricing. If you have an E5 license, you get everything."
"There are different licenses, such as E3 and E5."
"This product is included in the pricing for Windows."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Manufacturing Company
10%
Financial Services Firm
9%
Computer Software Company
8%
Comms Service Provider
8%
Construction Company
17%
Financial Services Firm
12%
Comms Service Provider
10%
Outsourcing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business82
Midsize Enterprise45
Large Enterprise96
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
McAfee Advanced Threat Defense
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trellix Advanced Threat Defense and other solutions. Updated: August 2026.
908,858 professionals have used our research since 2012.