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Microsoft Defender for Cloud vs Qualys VMDR comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jun 3, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
5.5
Qualys TotalCloud boosts efficiency, reduces manual effort, decreases risk, and offers significant cost savings with a notable ROI.
Sentiment score
7.1
Microsoft Defender for Cloud enhances ROI by improving security, productivity, and cost efficiency, despite perceived licensing costs.
Sentiment score
7.0
Qualys VMDR enhances ROI by streamlining management, improving compliance, reducing vulnerabilities, saving time, and minimizing breaches effectively.
It has saved about 90% of our time.
Senior Consultant at a consultancy with 10,001+ employees
TotalCloud has generated overall savings of 30 to 40 percent across various departments.
Security Manager at a consultancy with 10,001+ employees
CallStream helps us integrate and automate tasks.
Senior Security Consultant at CyberNxt Solutions LLP
Defender proactively indexes and analyzes documents, identifying potential threats even when inactive, enhancing preventative security.
Endpoint management at a government with 10,001+ employees
Identifying potential vulnerabilities has helped us avoid costly data losses.
Manager at CBTS
Compared to not having Microsoft Defender for Cloud in place, we definitely saw an advantage by not having downtime due to a security threat.
Principal Microsoft Consultant at MicroAge
We saw a return on investment through significant savings in time, money, and resources.
System Admin at a tech services company with 10,001+ employees
 

Customer Service

Sentiment score
7.4
Qualys TotalCloud support is praised for efficiency and staff knowledge but criticized for delays and inconsistent quality.
Sentiment score
6.3
Microsoft Defender for Cloud support is knowledgeable with effective documentation, but first-tier delays impact overall satisfaction.
Sentiment score
6.6
Qualys VMDR support is responsive and helpful, but users note occasional delays and suggest better response time and depth.
They are helpful, respond to my queries, and can answer any question.
Developer at a consultancy with 10,001+ employees
Qualys's tech support is highly responsive, providing multiple ways to interact with them.
Service Manager, Security Operations at CDA IT SOLUTIONS
Qualys' customer service provides quality answers, but the response time is long, even though it is within the SLA.
Works at a consultancy with 10,001+ employees
Since security is critical, we prefer a quicker response time.
Manager at CBTS
The support team was very responsive to queries.
Programme Manager- Cyber Fusion- Group CISO at a financial services firm with 10,001+ employees
They understand their product, but much like us, they struggle with the finer details, especially with new features.
Endpoint management at a government with 10,001+ employees
We usually get on calls with tech support, and they are very helpful.
Works at a comms service provider with 1-10 employees
The response time takes a while.
Security Engineer at a consultancy with 10,001+ employees
The technical support provided by Qualys is pretty good.
System Admin at a tech services company with 10,001+ employees
 

Scalability Issues

Sentiment score
7.8
Qualys TotalCloud excels in scalability, efficiently supporting diverse environments and business sizes, though it may require skilled management.
Sentiment score
7.5
Microsoft Defender for Cloud is highly scalable, seamlessly integrates across platforms, and efficiently handles growth, with room for feature improvement.
Sentiment score
7.9
Qualys VMDR is highly scalable, supporting numerous assets efficiently with customizable management and seamless cloud-based architecture.
We started our organization about nine months back. We started with about 30 users, and we now have more than 100 users.
CIO at a venture capital & private equity firm with 11-50 employees
Our organization currently uses it to manage over 1200 web applications.
Analyst, Information Security at Infosys
It is absolutely scalable, and I would rate its scalability as nine out of ten.
retired at a consultancy with 10,001+ employees
As we have reduced our on-premises infrastructure, it is about how we can migrate workloads to the cloud to make it easier, and then having everything fully encompassed and secured within that area makes it much easier for us to scale as needed and grow.
Principal Microsoft Consultant at MicroAge
We are using infrastructure as a code, so we do not have any scalability issues with Microsoft Defender for Cloud implementation because our cloud automatically does it.
Senior Cloud Platform Engineer at Deutsche Börse
It has multiple licenses and features, covering infrastructures from a hundred to five hundred virtual machines, without any issues.
Snr. Infrastructure Architect (Data Centre) at LogicEra
Scalability depends on the license and the number of assets being monitored.
System Admin at a tech services company with 10,001+ employees
Qualys VMDR can handle scalability, although increasing the inventory can raise the licensing costs.
Information Security Analyst at a tech services company with 51-200 employees
Qualys VMDR's scalability is good, and the customer support is good.
Cyber Security Solution Engineer at a computer software company with 201-500 employees
 

Stability Issues

Sentiment score
8.3
Qualys TotalCloud is highly stable with reliable support, 99.9% uptime, minimal bugs, and effective maintenance communication.
Sentiment score
7.6
Microsoft Defender for Cloud is stable and reliable, though minor update issues occur with older systems and internet latency.
Sentiment score
7.9
Qualys VMDR is highly stable, reliable, and effective, with minimal downtime and challenges mostly due to user-side issues.
Overall, the support provided has been excellent.
Analyst, Information Security at Infosys
It is a stable solution, which is why we chose it.
CIO at a venture capital & private equity firm with 11-50 employees
Continuous monitoring is crucial to ensure system stability and avoid vulnerabilities or threats.
Developer at a consultancy with 10,001+ employees
Defender's stability has been flawless for us.
Engineer at a computer software company with 201-500 employees
I have not experienced any crashes or downtime.
Head Of IT at Cirrus Response
Microsoft Defender for Cloud is very stable.
Cloud architect at a tech vendor with 1,001-5,000 employees
Qualys VMDR is stable.
Cyber Security Solution Engineer at a computer software company with 201-500 employees
 

Room For Improvement

Users suggest enhancing Qualys TotalCloud with clearer reports, better integration, intuitive UI, AI risk assessments, and improved documentation.
Microsoft Defender for Cloud needs improved customization, automation, UI performance, policy management, integration, AI functions, and reduced licensing complexities.
Qualys VMDR needs improved support, efficient reporting, UI, asset notifications, reduced tool dependency, better pricing, and comprehensive resources.
Ideally, the scanner should automatically detect and scan all subdomains, even if not explicitly defined, ensuring comprehensive vulnerability assessment.
Analyst, Information Security at Infosys
Ideally, updates should be more immediate, enabling quicker implementation of solutions.
Project Lead at Persistent Systems
Our goal is to integrate all these functions into Qualys, creating a single dashboard for comprehensive security monitoring and management.
Senior Information Security Engineer at a consultancy with 10,001+ employees
Microsoft, in general, could significantly improve its communication and support.
Endpoint management at a government with 10,001+ employees
It would be beneficial to streamline recommendations to avoid unnecessary alerts and to refine the severity of alerts based on specific environments or environmental attributes.
Works at Coca-Cola HBC
The artificial intelligence features could be expanded to allow the system to autonomously manage security issues without needing intervention from admins.
Cloud Consultant at i-Community AG
It does not automate patching unless the patch management module is purchased separately.
System Admin at a tech services company with 10,001+ employees
If AI features were integrated, it could enhance the capabilities significantly.
Information Security Analyst at a tech services company with 51-200 employees
One area where Qualys VMDR can be improved is the missing feature for deploying agents for over 1,000 assets, as we need to do it manually.
Cyber Security Solution Engineer at a computer software company with 201-500 employees
 

Setup Cost

Qualys TotalCloud's pricing is high yet justified by comprehensive features and flexibility, benefiting larger enterprises seeking robust security.
Microsoft Defender for Cloud offers flexible pricing but gets complex and costly, requiring careful evaluation, especially for advanced plans.
Qualys VMDR pricing is high for small businesses but offers flexibility, discounts, and comprehensive features for larger enterprises.
Qualys TotalCloud's pricing is currently acceptable, it is becoming increasingly expensive.
Senior Manager at a financial services firm with 10,001+ employees
Pricing is managed by our finance team; however, Qualys TotalCloud offers cost-effective licensing flexibility.
IT Manager at a consultancy with 10,001+ employees
Qualys TotalCloud is expensive, but it offers a premier solution with no headaches.
Vice President at Inspira Enterprise
Security has essentially no cost when compared to the cost of a breach.
Director, Cloud and Modern Workplace at Informanix Technology Group
Every time we consider expanding usage, we carefully evaluate the necessity due to cost concerns.
Programme Manager- Cyber Fusion- Group CISO at a financial services firm with 10,001+ employees
We appreciate the licensing approach based on employee count rather than a big enterprise license.
Manager, Microsoft Technology Alliance at Silverfort
I would rate the pricing between seven to eight out of ten.
System Admin at a tech services company with 10,001+ employees
I have a notion that Qualys might be more expensive than Rapid7.
Information Security Analyst at a tech services company with 51-200 employees
Qualys offers better pricing and is feature-packed compared to other tools.
Works at a comms service provider with 1-10 employees
 

Valuable Features

Qualys TotalCloud offers comprehensive vulnerability detection, cloud security management, and automation with insightful dashboards for efficient threat management.
Microsoft Defender for Cloud enhances security and compliance with AI-powered threat intelligence, automation, and multi-cloud integration for improved protection.
Qualys VMDR offers user-friendly management, real-time insights, and powerful integrations, significantly improving vulnerability prioritization and remediation efficiency.
This view of risk helps reduce the work we would have to do to combine multiple sources to prioritize risk.
Works at a consultancy with 10,001+ employees
It will help cybersecurity professionals monitor the cloud and find vulnerabilities.
Developer at a consultancy with 10,001+ employees
We are enjoying the new feature, FlexScan, which is valuable for Internet-facing VMs.
Senior Consultant at a consultancy with 10,001+ employees
The most valuable feature for me is the variety of APIs available.
Programme Manager- Cyber Fusion- Group CISO at a financial services firm with 10,001+ employees
This feature significantly aids in threat detection and enhances the user experience by streamlining security management.
Cloud Consultant at i-Community AG
The most valuable feature is the recommendations provided on how to improve security.
Cloud architect at a tech vendor with 1,001-5,000 employees
The prioritization of vulnerabilities has improved our remediation efforts by around thirty to thirty-five percent.
Works at a comms service provider with 1-10 employees
It impacts my workflow overall, with the patch management features as it has the missing patches listed in detail, making it easier to get a comprehensive report and providing some dashboards that offer visual representation.
JMS, RPSG Ventures Limited at RP Sanjiv Goenka Group
Qualys VMDR's continuous monitoring capabilities help us respond to emergent threats by enabling my team to reach out to the security engineers whenever there is any detection of a vulnerability, informing them about it, and creating an incident.
Soc Lead & Edr Administration at Persistent Systems
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Vulnerability Management
11th
Ranking in Container Security
11th
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
39
Ranking in other categories
Cloud Workload Protection Platforms (CWPP) (8th), Cloud Security Posture Management (CSPM) (8th), SaaS Security Posture Management (SSPM) (1st), Cloud-Native Application Protection Platforms (CNAPP) (6th)
Microsoft Defender for Cloud
Ranking in Vulnerability Management
5th
Ranking in Container Security
4th
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
89
Ranking in other categories
Container Management (7th), Cloud Workload Protection Platforms (CWPP) (1st), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (4th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (3rd)
Qualys VMDR
Ranking in Vulnerability Management
3rd
Ranking in Container Security
9th
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
96
Ranking in other categories
IT Asset Management (3rd), Configuration Management Databases (3rd), Risk-Based Vulnerability Management (1st)
 

Mindshare comparison

As of June 2026, in the Vulnerability Management category, the mindshare of Qualys TotalCloud is 1.0%, up from 0.9% compared to the previous year. The mindshare of Microsoft Defender for Cloud is 2.9%, down from 4.9% compared to the previous year. The mindshare of Qualys VMDR is 3.9%, down from 7.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Vulnerability Management Mindshare Distribution
ProductMindshare (%)
Qualys VMDR3.9%
Microsoft Defender for Cloud2.9%
Qualys TotalCloud1.0%
Other92.2%
Vulnerability Management
 

Featured Reviews

RO
IT Security Expert at Alior Bank S.A.
Unified risk scoring has improved our cloud visibility and simplifies remediation priorities
Qualys TotalCloud provides unified vulnerability and threat assessment across both IAS and SaaS. This solution provides a single prioritized view of risk, which helps reduce the work I would have to do. We are no longer based on CVSS; we are based on Qualys risk scoring, which is based on CVSS plus internal findings made by Qualys, and then assigns its own score. The TruRisk insight feature has found a small number of assets with high vulnerability scores, though I am cautious since some information is classified. Qualys TotalCloud has positively impacted our bank's performance, and we have definitely seen benefits after implementing this solution.
RW
Head Of IT at Cirrus Response
Cloud security has cut investigation time and now reveals threats faster but needs simpler oversight
When deploying AI applications, my key security concerns with Microsoft Defender for Cloud are data loss, leakage of data, and guardrails around the actual AI, and I am hoping that this is going to help me put those guardrails in place and identify data exfiltration. Microsoft Defender for Cloud has not helped me manage and secure multi-cloud environments, as we are 100 percent Microsoft and have not really got it in any other environment at all. I am not yet using the unified AI-powered security feature offered by Microsoft Defender for Cloud, but that is coming. I am not yet using the integrated XDR feature of Microsoft Defender for Cloud, but that is coming. I am not yet utilizing the GenAI threat protection features of Microsoft Defender for Cloud. That is also coming and a lot of that will come from learning it here. I have enabled the agentless scanning in my cloud environment with Microsoft Defender for Cloud. Assessing the impact on my workload protection without needing to install agents with Microsoft Defender for Cloud makes it a lot easier, but it also identifies a lot more, which puts more load on me sometimes. I would advise another organization considering Microsoft Defender for Cloud that it is the most logical route to follow if their whole ecosystem is Microsoft. It is easy to implement and it is very self-explanatory when doing it, making sense to just follow the steps as it is too simple, really. I would rate this review a 7.5 out of 10.
Vaibhav Ghule - PeerSpot reviewer
Soc Lead & Edr Administration at Persistent Systems
Continuous risk-based monitoring has strengthened incident response and vulnerability prioritization
I haven't explored Qualys VMDR's vulnerability lifecycle automation yet. One of my analysts mentioned that queries lack grouping operators in Qualys VMDR. From my experience, I would appreciate improvements in the query options in Qualys VMDR, specifically in the query-building process where I would need more features and operators. Additionally, we have been facing issues with Qualys on the cloud level. We cannot download the configuration profile from the cloud agent, and it is showing a pending action for download. During 2025, we noticed outages of Qualys a couple of times. I want to mention that there is an issue with receiving timely RCA deliveries. While this is not necessarily about the tool, it relates to support. The support has not been very responsive, and we are receiving RCAs a little delayed whenever we raise support cases or communicate with the TAMs. Additionally, the UI has a slight latency, which I and my team have experienced. They have also reported this latency issue when navigating through different pages.
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Top Industries

By visitors reading reviews
Manufacturing Company
18%
Financial Services Firm
14%
Construction Company
7%
Comms Service Provider
7%
Financial Services Firm
12%
Computer Software Company
10%
Manufacturing Company
9%
Government
6%
Financial Services Firm
16%
Manufacturing Company
7%
Computer Software Company
7%
Government
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise3
Large Enterprise29
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise12
Large Enterprise49
By reviewers
Company SizeCount
Small Business20
Midsize Enterprise12
Large Enterprise70
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
Areas that need improvement in every solution include the remediation part. The remediation steps should be simple en...
What is your primary use case for Qualys TotalCloud?
Our use case involves the assets that we have under cloud, the assets exposed to the internet, and the internal appli...
How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening acros...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup costs, and licensing was that the license cost was the only consideration. Setup an...
What needs improvement with Microsoft Defender for Cloud?
To improve Microsoft Defender for Cloud, I think pricing-wise, the license price is a little bit higher from an inges...
What is your experience regarding pricing and costs for Qualys VMDR?
My experience with pricing, setup cost, and licensing shows that we can consider both time and money saved.
What needs improvement with Qualys VMDR?
I haven't explored Qualys VMDR's vulnerability lifecycle automation yet. One of my analysts mentioned that queries la...
What advice do you have for others considering Qualys VMDR?
I have some understanding about PeerSpot, and I have visited the website. PeerSpot is similar to TrustRadius. It take...
 

Also Known As

Qualys TotalCloud with FlexScan
Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
Qualys VM, QualysGuard VM, Qualys Asset Inventory, Qualys Container Security
 

Interactive Demo

Demo not available
Demo not available
 

Overview

 

Sample Customers

Information Not Available
Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Agrokor Group, American Specialty Health, American State Bank, Arval, Life:), Axway, Bank of the West, Blueport Commerce, BSkyB, Brinks, CaixaBank, Cartagena, Catholic Health System, CEC Bank, Cegedim, CIGNA, Clickability, Colby-Sawyer College, Commercial Bank of Dubai, University of Utah, eBay Inc., ING Singapore, National Theatre, OTP Bank, Sodexo, WebEx
Find out what your peers are saying about Microsoft Defender for Cloud vs. Qualys VMDR and other solutions. Updated: June 2026.
900,644 professionals have used our research since 2012.