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Microsoft Defender for Cloud vs Qualys VMDR comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jan 25, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Cloud boosts security and efficiency, integrates with Azure, reduces costs, prevents breaches, and offers proactive defense.
Sentiment score
7.0
Qualys VMDR enhances ROI by streamlining management, improving compliance, reducing vulnerabilities, saving time, and minimizing breaches effectively.
Defender proactively indexes and analyzes documents, identifying potential threats even when inactive, enhancing preventative security.
Endpoint management at a government with 10,001+ employees
Identifying potential vulnerabilities has helped us avoid costly data losses.
Manager at CBTS
Compared to not having Microsoft Defender for Cloud in place, we definitely saw an advantage by not having downtime due to a security threat.
Principal Microsoft Consultant at MicroAge
We saw a return on investment through significant savings in time, money, and resources.
System Admin at a tech services company with 10,001+ employees
 

Customer Service

Sentiment score
6.3
Microsoft Defender for Cloud support is responsive at higher levels, but experiences vary with mixed satisfaction due to delays.
Sentiment score
6.6
Qualys VMDR support is responsive and helpful, but users note occasional delays and suggest better response time and depth.
Since security is critical, we prefer a quicker response time.
Manager at CBTS
The support team was very responsive to queries.
Programme Manager- Cyber Fusion- Group CISO at a financial services firm with 10,001+ employees
They understand their product, but much like us, they struggle with the finer details, especially with new features.
Endpoint management at a government with 10,001+ employees
We usually get on calls with tech support, and they are very helpful.
Works at a comms service provider with 1-10 employees
The response time takes a while.
Security Engineer at a consultancy with 10,001+ employees
The technical support provided by Qualys is pretty good.
System Admin at a tech services company with 10,001+ employees
 

Scalability Issues

Sentiment score
7.4
Microsoft Defender for Cloud is scalable, integrating across environments effortlessly, suitable for all enterprise sizes with flexible performance.
Sentiment score
7.9
Qualys VMDR is highly scalable, supporting numerous assets efficiently with customizable management and seamless cloud-based architecture.
As we have reduced our on-premises infrastructure, it is about how we can migrate workloads to the cloud to make it easier, and then having everything fully encompassed and secured within that area makes it much easier for us to scale as needed and grow.
Principal Microsoft Consultant at MicroAge
We are using infrastructure as a code, so we do not have any scalability issues with Microsoft Defender for Cloud implementation because our cloud automatically does it.
Senior Cloud Platform Engineer at Deutsche Börse
It has multiple licenses and features, covering infrastructures from a hundred to five hundred virtual machines, without any issues.
Snr. Infrastructure Architect (Data Centre) at LogicEra
Scalability depends on the license and the number of assets being monitored.
System Admin at a tech services company with 10,001+ employees
Qualys VMDR can handle scalability, although increasing the inventory can raise the licensing costs.
Information Security Analyst at a tech services company with 51-200 employees
Qualys VMDR's scalability is good, and the customer support is good.
Cyber Security Solution Engineer at a computer software company with 201-500 employees
 

Stability Issues

Sentiment score
7.5
Microsoft Defender for Cloud is stable and reliable, with minimal issues mainly during updates, ensuring strong user satisfaction.
Sentiment score
7.9
Qualys VMDR is highly stable, reliable, and effective, with minimal downtime and challenges mostly due to user-side issues.
Defender's stability has been flawless for us.
Engineer at a computer software company with 201-500 employees
Microsoft Defender for Cloud is very stable.
Cloud architect at a tech vendor with 1,001-5,000 employees
Microsoft sometimes changes settings or configurations without transparency.
Senior Cloud Platform Engineer at Deutsche Börse
Qualys VMDR is stable.
Cyber Security Solution Engineer at a computer software company with 201-500 employees
 

Room For Improvement

Microsoft Defender for Cloud users seek better automation, clarity, integration, AI features, and comprehensive analytics for improved security management.
Qualys VMDR needs improved support, efficient reporting, UI, asset notifications, reduced tool dependency, better pricing, and comprehensive resources.
Microsoft, in general, could significantly improve its communication and support.
Endpoint management at a government with 10,001+ employees
It would be beneficial to streamline recommendations to avoid unnecessary alerts and to refine the severity of alerts based on specific environments or environmental attributes.
Works at Coca-Cola HBC
The artificial intelligence features could be expanded to allow the system to autonomously manage security issues without needing intervention from admins.
Cloud Consultant at i-Community AG
It does not automate patching unless the patch management module is purchased separately.
System Admin at a tech services company with 10,001+ employees
If AI features were integrated, it could enhance the capabilities significantly.
Information Security Analyst at a tech services company with 51-200 employees
One area where Qualys VMDR can be improved is the missing feature for deploying agents for over 1,000 assets, as we need to do it manually.
Cyber Security Solution Engineer at a computer software company with 201-500 employees
 

Setup Cost

Microsoft Defender for Cloud is scalable, offering free and paid versions with costs averaging $15 monthly per server.
Qualys VMDR pricing is high for small businesses but offers flexibility, discounts, and comprehensive features for larger enterprises.
Security has essentially no cost when compared to the cost of a breach.
Director, Cloud and Modern Workplace at Informanix Technology Group
Every time we consider expanding usage, we carefully evaluate the necessity due to cost concerns.
Programme Manager- Cyber Fusion- Group CISO at a financial services firm with 10,001+ employees
We appreciate the licensing approach based on employee count rather than a big enterprise license.
Manager, Microsoft Technology Alliance at Silverfort
I would rate the pricing between seven to eight out of ten.
System Admin at a tech services company with 10,001+ employees
I have a notion that Qualys might be more expensive than Rapid7.
Information Security Analyst at a tech services company with 51-200 employees
Qualys offers better pricing and is feature-packed compared to other tools.
Works at a comms service provider with 1-10 employees
 

Valuable Features

Microsoft Defender for Cloud enhances security with AI-based threat detection, multi-cloud support, and a unified portal for comprehensive management.
Qualys VMDR offers user-friendly management, real-time insights, and powerful integrations, significantly improving vulnerability prioritization and remediation efficiency.
The most valuable feature for me is the variety of APIs available.
Programme Manager- Cyber Fusion- Group CISO at a financial services firm with 10,001+ employees
This feature significantly aids in threat detection and enhances the user experience by streamlining security management.
Cloud Consultant at i-Community AG
The most valuable feature is the recommendations provided on how to improve security.
Cloud architect at a tech vendor with 1,001-5,000 employees
The prioritization of vulnerabilities has improved our remediation efforts by around thirty to thirty-five percent.
Works at a comms service provider with 1-10 employees
It impacts my workflow overall, with the patch management features as it has the missing patches listed in detail, making it easier to get a comprehensive report and providing some dashboards that offer visual representation.
JMS, RPSG Ventures Limited at RP Sanjiv Goenka Group
Qualys VMDR's continuous monitoring capabilities help us respond to emergent threats by enabling my team to reach out to the security engineers whenever there is any detection of a vulnerability, informing them about it, and creating an incident.
Soc Lead & Edr Administration at Persistent Systems
 

Categories and Ranking

Microsoft Defender for Cloud
Ranking in Vulnerability Management
8th
Ranking in Container Security
7th
Average Rating
8.0
Reviews Sentiment
6.8
Number of Reviews
87
Ranking in other categories
Container Management (7th), Cloud Workload Protection Platforms (CWPP) (1st), Cloud Security Posture Management (CSPM) (4th), Cloud-Native Application Protection Platforms (CNAPP) (4th), Data Security Posture Management (DSPM) (5th), Microsoft Security Suite (7th), Compliance Management (4th), Cloud Detection and Response (CDR) (2nd)
Qualys VMDR
Ranking in Vulnerability Management
3rd
Ranking in Container Security
9th
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
96
Ranking in other categories
IT Asset Management (3rd), Configuration Management Databases (3rd), Risk-Based Vulnerability Management (1st)
 

Mindshare comparison

As of February 2026, in the Vulnerability Management category, the mindshare of Microsoft Defender for Cloud is 3.6%, down from 4.7% compared to the previous year. The mindshare of Qualys VMDR is 5.0%, down from 9.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Vulnerability Management Market Share Distribution
ProductMarket Share (%)
Qualys VMDR5.0%
Microsoft Defender for Cloud3.6%
Other91.4%
Vulnerability Management
 

Featured Reviews

David Birhange - PeerSpot reviewer
Director, Cloud and Modern Workplace at Informanix Technology Group
Brings together cloud security insights through a unified view and supports agentless protection for virtual machines
Copilot and similar features are already being used, though not necessarily for Microsoft Defender for Cloud specifically. We are trying to get more experience before rolling out most of Microsoft Defender for Cloud's AI capabilities. This is definitely on our to-do list, and the priority is urgent as we seek to learn more about these capabilities. The GenAI threat protection from Microsoft Defender for Cloud has not been enabled yet. There are many unknowns with AI applications. AI agents will operate while you're not present, whether you are sleeping or awake, and it's unclear whether there would be any exfiltration of data or how data is being managed. Microsoft Purview is being used extensively, and there is significant development going on with DSPM that will be rolled out to address security concerns. Data labeling and proper demarcation for sensitivity of data before it is received are being actively pursued.
Vaibhav Ghule - PeerSpot reviewer
Soc Lead & Edr Administration at Persistent Systems
Continuous risk-based monitoring has strengthened incident response and vulnerability prioritization
I haven't explored Qualys VMDR's vulnerability lifecycle automation yet. One of my analysts mentioned that queries lack grouping operators in Qualys VMDR. From my experience, I would appreciate improvements in the query options in Qualys VMDR, specifically in the query-building process where I would need more features and operators. Additionally, we have been facing issues with Qualys on the cloud level. We cannot download the configuration profile from the cloud agent, and it is showing a pending action for download. During 2025, we noticed outages of Qualys a couple of times. I want to mention that there is an issue with receiving timely RCA deliveries. While this is not necessarily about the tool, it relates to support. The support has not been very responsive, and we are receiving RCAs a little delayed whenever we raise support cases or communicate with the TAMs. Additionally, the UI has a slight latency, which I and my team have experienced. They have also reported this latency issue when navigating through different pages.
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Top Industries

By visitors reading reviews
Financial Services Firm
13%
Computer Software Company
11%
Manufacturing Company
9%
Government
6%
Financial Services Firm
16%
Computer Software Company
10%
Manufacturing Company
7%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business27
Midsize Enterprise10
Large Enterprise49
By reviewers
Company SizeCount
Small Business20
Midsize Enterprise12
Large Enterprise70
 

Questions from the Community

How is Prisma Cloud vs Azure Security Center for security?
Azure Security Center is very easy to use, integrates well, and gives very good visibility on what is happening across your ecosystem. It also has great remote workforce capabilities and supports a...
What is your experience regarding pricing and costs for Microsoft Defender for Cloud?
My experience with pricing, setup cost, and licensing for Microsoft Defender for Cloud was pretty straightforward. We did have a consultation with a third party to go over different tiers and produ...
What needs improvement with Microsoft Defender for Cloud?
Microsoft Defender for Cloud can be improved. An additional feature that should be included in the next release is Zero Trust, similar to ThreatLocker software.
What do you like most about Qualys VMDR?
I like that we have many scanners and channels that don't overload. It helps us scan and track easily. Also, the tagging system is good for tagging. We can still use QualysAgent task ID tools even ...
What is your experience regarding pricing and costs for Qualys VMDR?
My experience with pricing, setup cost, and licensing shows that we can consider both time and money saved.
What needs improvement with Qualys VMDR?
I haven't explored Qualys VMDR's vulnerability lifecycle automation yet. One of my analysts mentioned that queries lack grouping operators in Qualys VMDR. From my experience, I would appreciate imp...
 

Also Known As

Microsoft Azure Security Center, Azure Security Center, Microsoft ASC, Azure Defender
Qualys VM, QualysGuard VM, Qualys Asset Inventory, Qualys Container Security
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Microsoft Defender for Cloud is trusted by companies such as ASOS, Vatenfall, SWC Technology Partners, and more.
Agrokor Group, American Specialty Health, American State Bank, Arval, Life:), Axway, Bank of the West, Blueport Commerce, BSkyB, Brinks, CaixaBank, Cartagena, Catholic Health System, CEC Bank, Cegedim, CIGNA, Clickability, Colby-Sawyer College, Commercial Bank of Dubai, University of Utah, eBay Inc., ING Singapore, National Theatre, OTP Bank, Sodexo, WebEx
Find out what your peers are saying about Microsoft Defender for Cloud vs. Qualys VMDR and other solutions. Updated: January 2026.
881,707 professionals have used our research since 2012.