Microsoft Defender for Office 365 vs Morphisec comparison

Microsoft Defender for Offi...

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Executive SummaryUpdated on Dec 1, 2024

Morphisec and Microsoft Defender for Office 365 are competitive solutions in cybersecurity. Morphisec offers strong zero-day attack prevention without affecting performance, potentially giving it an edge where endpoint performance is critical. In email threat prevention, Microsoft Defender for Office 365 seems to lead, excelling in areas like anti-phishing and safe attachment handling, making it well-suited for Microsoft-integrated environments.

Features: Morphisec provides powerful defense against zero-day threats, operating without the need for signatures, and is designed to protect without impacting system performance. It delivers comprehensive event visibility, integrating seamlessly with Microsoft Defender in a single dashboard. Microsoft Defender for Office 365 stands out in email security, featuring anti-phishing, safe links, and safe attachments, along with deep integration across Microsoft platforms to offer enhanced protection within Office 365 and related environments.

Room for Improvement: Morphisec could benefit from a more advanced alert system, quicker updates, and improved response times from technical support. There's a demand for broader antivirus integrations and faster customer service resolution. Microsoft Defender for Office 365 users desire better spam filtering, more accessible integrations across diverse platforms, and improved reporting on security threats, alongside more flexible pricing options.

Ease of Deployment and Customer Service: Morphisec is adaptable across both public and private cloud infrastructures, and while its customer service is praised, some users experience time zone delays with support. Microsoft Defender for Office 365 offers straightforward deployment within the Microsoft ecosystem but could improve the speed of resolving complex technical issues.

Pricing and ROI: Morphisec is valued for its transparent and competitive pricing, delivering significant ROI by reducing the need for dedicated management resources. Its cost efficiency and protective capabilities against high-cost threats are appreciated. Microsoft Defender for Office 365's cost is typically included in the Office 365 suite, complicating direct cost evaluation. Its substantial integration with Microsoft services can justify the expense, but some users find it costly, particularly smaller enterprises.

To learn more, read our detailed Microsoft Defender for Office 365 vs. Morphisec Report (Updated: September 2026).

Microsoft Defender for Office 365 vs. Morphisec

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Helped 913,806 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Microsoft Defender for Offi...

Ranking in Advanced Threat Protection (ATP)

3rd

Average Rating

8.4

Reviews Sentiment

6.8

Number of Reviews

Ranking in other categories

Email Archiving (1st), Email Security (2nd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (2nd)

Morphisec

Ranking in Advanced Threat Protection (ATP)

30th

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Vulnerability Management (57th), Endpoint Protection Platform (EPP) (45th), Endpoint Detection and Response (EDR) (59th), Cloud Workload Protection Platforms (CWPP) (34th), Threat Deception Platforms (13th)

Mindshare comparison

As of September 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 6.1%, down from 13.2% compared to the previous year. The mindshare of Morphisec is 2.3%, up from 0.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Advanced Threat Protection (ATP) Mindshare Distribution
Product	Mindshare (%)
Microsoft Defender for Office 365	6.1%
Morphisec	2.3%
Other	91.6%

Advanced Threat Protection (ATP)

Featured Reviews

Emeka Ndulu

Cloud Solutions Architect at a tech services company with 201-500 employees

Improves threat visibility and response while reducing manual tasks and training users against phishing

I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Read full review

Rick Schibler

VP of Information Technology at Kentucky Trailer

Offers in-memory protection at a lower price than competitors

Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"The good part is that you don't have to configure it, which is very convenient."

"The product is not resource-intensive."

"My experience with customer support and technical support for Microsoft Defender for Office 365 has been excellent."

"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."

"The coolest feature of Microsoft Defender for Office 365 is its ability to look for phishing emails."

"The initial setup is straightforward. You just add the license, click it, and then you can set up the rules. It is quite simple."

"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."

"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."

More Microsoft Defender for Office 365 pros

"Morphisec makes it super easy for our IT team to prevent breaches of critical systems; it is a one-click install, then it takes care of the rest."

"We don't have to do anything as a user or as an admin. It does everything by default with its coding and inbuilt AI-based intelligence. We don't have to instruct it about what to do. It automatically takes corrective actions and quarantines or deletes a virus, malware, etc. That is the best part that I like about it."

"The ability to stop attacks without having to detect or have a signature for the attack is the most valuable feature."

"We have not had one machine that has been taken down due to malware now in almost four and a half years, with 600 machines that we don't have routine infections on because nothing can execute."

"Morphisec makes use of deterministic attack prevention that doesn’t require investigation of security alerts. It changes the memory locations of where certain applications run. If you think of Excel, opening a PDF, running an Excel macro, or opening a webpage and clicking on a link, all of those actions run in a certain area of memory. Morphisec changes the memory locations of where those run."

"The fact that Morphisec uses deterministic attack prevention that does not require human intervention has affected our security team's operations by making things much simpler. We don't have to really track down various alerts anymore, they've just stopped. At that point, we can go in and we can clean up whatever needs to be cleaned up. There are some things that Morphisec detects that we can't really remove, it's parts of Internet Explorer, but it's being blocked anyway. So we're happy with that."

"Since we started using Morphisec, that hasn't happened even once."

"Morphisec provides full visibility into security events from Microsoft Defender and Morphisec in one dashboard. Defender and Morphisec are integrated. It's important because it lowers the total cost of maintenance on the engineer's time, more or less. So the administrative time is dramatically reduced in maintaining the product. This saves an engineer around four to five hours a week."

More Morphisec pros

Cons

"We are waiting for better software to block viruses."

"The cost of Security Copilot is up there right now, and I think it needs to come down for more people to adopt."

"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."

"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."

"You should be able to deploy Defender for every subscription without the need to add servers."

"The phishing and spam filters could use some improvement."

"The pre-sales cost calculations could be more transparent."

"If you look at other products, such as Wiz or Palo Alto's cloud, because they also have similar components in terms of how they protect cloud infrastructure or enable cloud security, Microsoft Defender for Office 365 is not up to that extent."

More Microsoft Defender for Office 365 cons

"It might be a bit much to ask, but we are now beginning to use Morphisec Scout, which provides vulnerability information. At this time, it's recognizing vulnerabilities and reporting them to us, but it's not necessarily resolving them. There's still a separate manual process to resolve those vulnerabilities, primarily through upgrades. We have to do that outside of Morphisec. If Morphisec could somehow have that capability built into it, that would be very effective."

"It would be useful for them if they had some kind of network discovery."

"It would be useful for them if they had some kind of network discovery. That kind of functionality I think would give IT administrators a little bit more confidence that they have 100 percent coverage, and it gives them something to audit against. Network discovery would be one area I would definitely suggest that they put some effort into."

"Morphisec is a venture startup. They are still early in their growth stage. They need to get mature on their customer support and on how they interface with system tools."

"Sometimes it generates false positive alerts. They need to continue working on that. They have provided solutions for it and have fixed issues with updated versions. The service is quite good but they need to work on it more so that there are no false positive alerts."

"Some of the filters for the console need improvement. There are alerts that show up and just being able to acknowledge that we've seen those and not turn them off, but dismiss them, would be a huge benefit."

"The only area that really needs improvement is the reporting functionality. Gathering the detailed information that is in the system for an executive, or for me as a director, could be better. Some of the interface and reporting aspects are a little bit dated. They're working on it."

"We have only had four attacks in the last year, "attacks" being some benign PDF from a vendor that, for some reason, were triggered. There were no actual attacks. They were just four false positives, or something lowly like adware. There have been false positives with both the on-premises solution and the cloud solution."

More Morphisec cons

Pricing and Cost Advice

"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."

"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."

"I was working in the government and it was too expensive for us to use our Microsoft products."

"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."

"The license is expensive because the cost is based on the number of users."

"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."

"The pricing has become expensive."

"The pricing is normal. Considering its popularity, it's not overpriced."

More Microsoft Defender for Office 365 pricing and cost advice

"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."

"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."

"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."

"The pricing is definitely fair for what it does."

"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."

"We are still using a separate tool. I know for our 600 or I think we're actually licensed for up to 700 users, it runs me 23 or $24,000 a year. When you're talking to that many users plus servers being protected, that's well worth the investment for that dollar amount."

"It is an annual subscription basis per device. For the devices that we have in scope right now, it is about $25,000 a year."

"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."

More Morphisec pricing and cost advice

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Top Industries

By visitors reading reviews

Computer Software Company

11%

Manufacturing Company

10%

Financial Services Firm

Comms Service Provider

Outsourcing Company

15%

Manufacturing Company

13%

Construction Company

12%

Comms Service Provider

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	24
Midsize Enterprise	11
Large Enterprise	32

By reviewers
Company Size	Count
Small Business	5
Midsize Enterprise	8
Large Enterprise	8

Questions from the Community

What is your experience regarding pricing and costs for Microsoft Defender for Office 365?

My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as a standalone product. It's very competitive compared to what competitors are ch...

See all answers

What needs improvement with Microsoft Defender for Office 365?

I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware. We are seeing a lot more malware-less emails that Defender for Offi...

See all answers

What is your primary use case for Microsoft Defender for Office 365?

My main use cases for Microsoft Defender for Office 365 include email hygiene.

See all answers

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Comparisons

Proofpoint Email Protection vs Microsoft Defender for Office 365

Compared 5% of the time

Check Point Email Security (formerly Harmony Email & Collaboration) vs Microsoft Defender for Office 365

Compared 4% of the time

Mimecast Advanced Email Security vs Microsoft Defender for Office 365

Compared 3% of the time

Cisco Secure Email vs Microsoft Defender for Office 365

Compared 3% of the time

Barracuda Email Protection vs Microsoft Defender for Office 365

Compared 3% of the time

More Microsoft Defender for Office 365 Competitors

Symantec Endpoint Security vs Morphisec

Compared 9% of the time

FortiCNAPP vs Morphisec

Compared 5% of the time

CrowdStrike Falcon vs Morphisec

Compared 4% of the time

Orca Security vs Morphisec

Compared 3% of the time

Prisma Cloud by Palo Alto Networks vs Morphisec

Compared 3% of the time

More Morphisec Competitors

Product Reports

Microsoft Defender for Office 365

Download Microsoft Defender for Office 365 product report

Microsoft Defender for Office 365 report

Download Morphisec product report

Also Known As

MS Defender for Office 365

Morphisec, Morphisec Moving Target Defense

Overview

Microsoft Defender for Office 365 offers real-time email security, enhancing threat detection through integration within the Microsoft ecosystem. Its user-friendly interface and central management streamline operations, providing robust protection against phishing, ransomware, and malware.

Defender for Office 365 is focused on efficiently securing email communication by safeguarding against phishing, malware, and spam threats. With its strong integration with other Microsoft services, it is tailored to improve endpoint security and identity protection. Its centralized management tools simplify threat prioritization, while the automated threat response capabilities ensure swift actions against potential risks. Organizations leverage its capabilities to efficiently manage their cybersecurity efforts, particularly in remote work environments, while maintaining a secure system across Office 365 applications and Azure-hosted services.

What are the key features?

Real-time Email Protection: Continuously monitors and protects email communications.
Safe Attachments and Links: Scans attachments and links for potential threats.
Anti-Phishing Measures: Provides tools to detect and block phishing attempts.
Integration with Microsoft Services: Seamlessly connects with other Microsoft applications for enhanced security.
Automated Threat Responses: Activates immediate responses to detected threats.

What benefits should users expect from reviews?

Time Savings: Automates processes to reduce manual threat management efforts.
Improved Cybersecurity: Strengthens organizational defenses against various cyber threats.
Efficient Remote Work: Enhances protection for remote teams and virtual collaborations.
Comprehensive Coverage: Extends protection across Office 365 and Azure services.

Implementations of Defender for Office 365 vary across industries, optimizing email security for sectors such as finance, healthcare, and education. In finance, it aids in protecting sensitive financial data from phishing and fraud. Healthcare benefits from secure communications, ensuring patient data privacy. Educational institutions use it to maintain secure virtual learning environments against cyber threats.

Microsoft

Morphisec enhances security with its signatureless attack prevention, integrating smoothly with Microsoft Defender. Users benefit from real-time threat detection and seamless system integration, protecting against zero-day threats and ransomware across networks.

Morphisec's security solution focuses on preventing cyber threats without requiring threat signatures or user action. Its integration with Microsoft Defender offers simplified visibility and management while delivering quick responses. Lightweight in nature, Morphisec ensures zero performance degradation and employs in-memory protection along with Moving Target Defense. This approach effectively counters zero-day threats and ransomware, maintaining a user-centric dashboard that eases administrative workloads. Morphisec's easy deployment also enables small teams to manage risks and uphold robust security measures efficiently.

What are Morphisec's key features?

Signatureless Threat Prevention: Stops attacks without threat signatures or user interaction.
Microsoft Defender Integration: Provides unified management and quick response capabilities.
In-Memory Protection: Shields against zero-day and ransomware threats efficiently.
Moving Target Defense: Minimizes exposure to in-memory attacks.
User-Friendly Dashboard: Simplifies administration by reducing burdens.
Easy Deployment: Facilitates straightforward setup for small teams.

What benefits and ROI should be considered in user reviews?

Real-Time Detection: Immediate identification of threats enhances proactive threat management.
Seamless Integration: Compatible with existing systems, reducing delay risks.
Cloud-Based Updates: Ensures current protection with minimal manual input.
Multi-Layered Security: Adds a solid last defense layer, supplementing other antivirus solutions.

Morphisec is widely used across industries like financial services, healthcare, and manufacturing to bolster defenses against malware and ransomware. Its deployment spans workstations and servers, integrating efficiently into existing infrastructures. Industries value real-time threat detection, ease of deployment, and cloud-based updates, noting its ability to identify threats missed by other antivirus solutions.

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.

Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center

Microsoft Defender for Office 365 vs. Morphisec