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Microsoft Defender for Office 365 vs Morphisec comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Email Security (2nd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (1st)
Morphisec
Ranking in Advanced Threat Protection (ATP)
31st
Average Rating
9.2
Reviews Sentiment
7.4
Number of Reviews
21
Ranking in other categories
Vulnerability Management (57th), Endpoint Protection Platform (EPP) (49th), Endpoint Detection and Response (EDR) (61st), Cloud Workload Protection Platforms (CWPP) (34th), Threat Deception Platforms (21st)
 

Mindshare comparison

As of March 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 7.6%, down from 15.9% compared to the previous year. The mindshare of Morphisec is 1.9%, up from 0.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3657.6%
Morphisec1.9%
Other90.5%
Advanced Threat Protection (ATP)
 

Featured Reviews

Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
Rick Schibler - PeerSpot reviewer
VP of Information Technology at Kentucky Trailer
Offers in-memory protection at a lower price than competitors
Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
"Microsoft Defender for Office 365's most valuable features are safe attachments and safe links."
"The basic features are okay and I'm satisfied with the Defender."
"The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance."
"The good part is that you don't have to configure it, which is very convenient."
"Does a thorough job of examining email and URLs for malicious content."
"Defender helps us prioritize threats across our organization."
"Microsoft Defender for Office 365 has improved my organization's security. It makes it easier to manage the infrastructure without the help of third-party applications."
"It also provides full visibility into security events from Microsoft Defender and Morphisec in one dashboard. We've always had that capability with Morphisec. The more recent version appears to do that even a little bit more natively and it's given us visibility that we didn't have otherwise."
"Morphisec provides full visibility into security events from Microsoft Defender and Morphisec in one dashboard. Defender and Morphisec are integrated. It's important because it lowers the total cost of maintenance on the engineer's time, more or less. So the administrative time is dramatically reduced in maintaining the product. This saves an engineer around four to five hours a week."
"Morphisec makes it very easy for IT teams of any size to prevent breaches of critical systems because of the design of their tool. When we evaluated Morphisec, the CIO and I sat and listened. What attracted us to them is the fact that it stops activity at the point of detection. That saves a lot of time because now we are not investigating and trying to trace down what to turn off. We have already prevented it, which makes it very much safer and more secure."
"The fact that Morphisec uses deterministic attack prevention that does not require human intervention has affected our security team's operations by making things much simpler. We don't have to really track down various alerts anymore, they've just stopped. At that point, we can go in and we can clean up whatever needs to be cleaned up. There are some things that Morphisec detects that we can't really remove, it's parts of Internet Explorer, but it's being blocked anyway. So we're happy with that."
"What's valuable is really the whole kit and caboodle of the Morphisec agent. What it does is genius, in a way, until the bad guys get wise to it. You set it up and then you watch the dashboard. There isn't really much tinkering."
"Morphisec stops attacks without needing to know what type of threat it is, just that it is foreign. It is based on injections, so it would know when a software launches. If a software launches and something else also launches, then it would count that as anomalous and block it. Because the software looks at the code, and if it executes something else that is not related, then Morphisec would block it. That is how it works."
"Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it."
"It provides full visibility into security events and from both solutions in one dashboard. I'm not a big security guy, if I have a threat that looks like there's a problem, I will ask Morphisec to dissect it for me, and tell me what might be happening. Because it tends to be all hash codes, so I can tell what's going on. They've been pretty good with that."
 

Cons

"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"From a development point of view, if I wanted to do development on my actual machine where Defender is, the organization can set certain policies or Defender makes that prohibitive."
"Microsoft Defender for Office 365 is not up to the mark in comparison with Wiz or Palo Alto."
"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"The visibility into threats is not up to the mark, as I do not have control. I rate my experience with Microsoft Defender for Office 365 as six out of ten due to troubleshooting and pricing concerns."
"We need to be able to whitelist data at the backend."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"Configuration at the mid-level could be improved for the support team."
"I haven't been able to get the cloud deployment to work. When there's an update, I'm supposed to be able to roll it out for the cloud solution, but right now I'm continuing to use our SCCM solution to update it."
"Those are some of the features that I was looking for on my on-prem platform that they've already instituted in the cloud and that I'm sure will be instituting on their on-prem platform as well. Having to have an on-prem server required a lot of administration. Being able to push that to the cloud and have it managed up there for us is a real nice addition."
"We have only had four attacks in the last year, "attacks" being some benign PDF from a vendor that, for some reason, were triggered. There were no actual attacks. They were just four false positives, or something lowly like adware. There have been false positives with both the on-premises solution and the cloud solution."
"Morphisec is a venture startup. They are still early in their growth stage. They need to get mature on their customer support and on how they interface with system tools. For example, they need to get multifactor in place and an API for the major multi-factor systems, e.g., Okta, Duo, Ping, and Microsoft. They don't have them built in yet. They are working on them. It is just not there yet. Also, their stability, customer support, and processes need improvement, which is just part of maturity."
"The only area that really needs improvement is the reporting functionality. Gathering the detailed information that is in the system for an executive, or for me as a director, could be better. Some of the interface and reporting aspects are a little bit dated. They're working on it."
"Some of the filters for the console need improvement. There are alerts that show up and just being able to acknowledge that we've seen those and not turn them off, but dismiss them, would be a huge benefit."
"We wanted to have multi-tenants in their cloud platform, so every entity can look into their own systems and not see other systems in other entities. I have a beta version on that now. I would like them to incorporate that in the cloud solution."
"Right now, it's just their auto-update feature. I know they are currently working on that. When they release a new version of the threat prevention platform, I do have to update that, rolling out to every computer. They have said, "From version 5, you would be able to do an auto-update." While this is very minor, that is the only thing that I would say needs to be upgraded. It would just make life a lot easier for other IT teams. However, I have simplified the process, so all I need to do is just download one file."
 

Pricing and Cost Advice

"The pricing has become expensive."
"It's a user-base subscription."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"The product is expensive."
"I know that the product is incredibly expensive."
"The pricing is definitely fair for what it does."
"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."
"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."
"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."
"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."
"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."
"It does not have multi-tenants. If South Africa wants to show only the machines that they have, they need their own cloud incidence. It is not possible to have that in a single cloud incidence with multiple tenants in it, instead you need to have multiple cloud incidences. Then, if you have that, it will be more expensive. However, they are going to change that, which is good."
"We are still using a separate tool. I know for our 600 or I think we're actually licensed for up to 700 users, it runs me 23 or $24,000 a year. When you're talking to that many users plus servers being protected, that's well worth the investment for that dollar amount."
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Top Industries

By visitors reading reviews
Computer Software Company
13%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Outsourcing Company
18%
Manufacturing Company
11%
Financial Services Firm
8%
Computer Software Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise10
Large Enterprise31
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise8
Large Enterprise8
 

Questions from the Community

What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What is your primary use case for Microsoft Defender for Office 365?
My use case for Microsoft Defender for Office 365 is for email protection, safe links, protection of links, documents, protecting my documents, and protecting attachments. I also use it to conduct ...
Ask a question
Earn 20 points
 

Also Known As

MS Defender for Office 365
Morphisec, Morphisec Moving Target Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Morphisec and other solutions. Updated: March 2026.
884,873 professionals have used our research since 2012.