Microsoft Defender for Office 365 vs Morphisec comparison

Microsoft Defender for Offi...

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Executive SummaryUpdated on Dec 1, 2024

Morphisec and Microsoft Defender for Office 365 are competitive solutions in cybersecurity. Morphisec offers strong zero-day attack prevention without affecting performance, potentially giving it an edge where endpoint performance is critical. In email threat prevention, Microsoft Defender for Office 365 seems to lead, excelling in areas like anti-phishing and safe attachment handling, making it well-suited for Microsoft-integrated environments.

Features: Morphisec provides powerful defense against zero-day threats, operating without the need for signatures, and is designed to protect without impacting system performance. It delivers comprehensive event visibility, integrating seamlessly with Microsoft Defender in a single dashboard. Microsoft Defender for Office 365 stands out in email security, featuring anti-phishing, safe links, and safe attachments, along with deep integration across Microsoft platforms to offer enhanced protection within Office 365 and related environments.

Room for Improvement: Morphisec could benefit from a more advanced alert system, quicker updates, and improved response times from technical support. There's a demand for broader antivirus integrations and faster customer service resolution. Microsoft Defender for Office 365 users desire better spam filtering, more accessible integrations across diverse platforms, and improved reporting on security threats, alongside more flexible pricing options.

Ease of Deployment and Customer Service: Morphisec is adaptable across both public and private cloud infrastructures, and while its customer service is praised, some users experience time zone delays with support. Microsoft Defender for Office 365 offers straightforward deployment within the Microsoft ecosystem but could improve the speed of resolving complex technical issues.

Pricing and ROI: Morphisec is valued for its transparent and competitive pricing, delivering significant ROI by reducing the need for dedicated management resources. Its cost efficiency and protective capabilities against high-cost threats are appreciated. Microsoft Defender for Office 365's cost is typically included in the Office 365 suite, complicating direct cost evaluation. Its substantial integration with Microsoft services can justify the expense, but some users find it costly, particularly smaller enterprises.

To learn more, read our detailed Microsoft Defender for Office 365 vs. Morphisec Report (Updated: June 2026).

Microsoft Defender for Office 365 vs. Morphisec

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Helped 900,644 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Microsoft Defender for Offi...

Ranking in Advanced Threat Protection (ATP)

2nd

Average Rating

8.4

Reviews Sentiment

6.8

Number of Reviews

Ranking in other categories

Email Archiving (1st), Email Security (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (2nd)

Morphisec

Ranking in Advanced Threat Protection (ATP)

31st

Average Rating

9.2

Reviews Sentiment

7.4

Number of Reviews

Ranking in other categories

Vulnerability Management (58th), Endpoint Protection Platform (EPP) (47th), Endpoint Detection and Response (EDR) (60th), Cloud Workload Protection Platforms (CWPP) (35th), Threat Deception Platforms (13th)

Mindshare comparison

As of June 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 6.5%, down from 14.6% compared to the previous year. The mindshare of Morphisec is 2.1%, up from 0.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Advanced Threat Protection (ATP) Mindshare Distribution
Product	Mindshare (%)
Microsoft Defender for Office 365	6.5%
Morphisec	2.1%
Other	91.4%

Advanced Threat Protection (ATP)

Featured Reviews

Emeka Ndulu

Cloud Solutions Architect at a tech services company with 201-500 employees

Improves threat visibility and response while reducing manual tasks and training users against phishing

I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Read full review

Rick Schibler

VP of Information Technology at Kentucky Trailer

Offers in-memory protection at a lower price than competitors

Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"The DLP feature of Microsoft Defender for Office 365 is valuable, and we also use the DLP feature for email real-time detection."

"Microsoft Defender for Office 365 saves me time; it does save a lot of time, especially with the automation."

"The most valuable feature of Microsoft Defender for Office 365 is the ease of use."

"I would say that 90% of the spam and phishing attack emails get blocked right off the bat."

"Defender enables us to secure all 365-related activity from a single place. It gives us visibility into everything happening in Outlook, protecting us against phishing and other email-based threats. Defender helps us detect any suspicious behaviors."

"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."

"Microsoft Defender for Office 365 has improved my organization's security. It makes it easier to manage the infrastructure without the help of third-party applications."

"Does a thorough job of examining email and URLs for malicious content."

More Microsoft Defender for Office 365 pros

"Morphisec gives me even more than Microsoft can give me, even if I were to pay."

"We have seen it successfully block attacks that a traditional antivirus did not pick up."

"Morphisec also provides full visibility into security events for Microsoft Defender and Morphisec in one dashboard... in the single pane of glass provided by Morphisec, it's all right there at your fingertips: easy to access and easy to understand. And if you choose to go down further to know everything from the process to the hash behind it, you can."

"We haven't had any cybersecurity incidents on machines running Morphisec."

"Morphisec has absolutely helped save money on our security stack. The ransomware at the end of the day can cost organizations millions upon millions of dollars. Investing in tools like Morphisec is a great reduction in that cost. If I can spend $10,000 in a year to protect assets that could be ransomed for $20,000,000, that's definitely a bet that one should pursue. Morphisec absolutely it's worth the investment."

"In a month, we are saving the effort of four to five days, and earlier we used to have a dedicated person and now we don't need a dedicated resource, which has reduced our security spending and we are saving approximately $600 a month."

"With Morphisec, at least when it does happen, I feel confident that we have in place solutions that will not only prevent it, but also let us know when something has happened."

"We have not had one machine that has been taken down due to malware now in almost four and a half years, with 600 machines that we don't have routine infections on because nothing can execute."

More Morphisec pros

Cons

"I was looking for some advanced features, like if I would receive an email that contains a legitimate file type, but the content is malicious, how I can protect against that?"

"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."

"Microsoft Defender for Office 365 should be more proactive."

"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."

"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."

"The certification training for Defender for 365 needs to be deeper and incorporate Sentinel. I took all the security courses except one, and Sentinel isn't included."

"Configuration at the mid-level could be improved for the support team."

"The GUI is sometimes slow to fetch the device report and could be improved."

More Microsoft Defender for Office 365 cons

"We wanted to have multi-tenants in their cloud platform, so every entity can look into their own systems and not see other systems in other entities. I have a beta version on that now. I would like them to incorporate that in the cloud solution."

"We have only had four attacks in the last year, "attacks" being some benign PDF from a vendor that, for some reason, were triggered. There were no actual attacks. They were just four false positives, or something lowly like adware. There have been false positives with both the on-premises solution and the cloud solution."

"If anything, tech support might be their weakest link. The process of getting someone involved sometimes takes a little time. It seems to me that they should have all the data they need to let me know whether an alert is legitimate or not, but they tend to need a lot of information from me to get to the bottom of something. It usually takes a little longer than I would expect."

"From a company standpoint, a little more interaction with the customers throughout the year might be beneficial. I would like check-ins from the Morphisec account executives about any type of Morphisec news as well as a bit more interaction with customers throughout the year to know if anything new is coming out with Morphisec, e.g., what they are working on in regards to their development roadmap. We tend not to get that up until the time that we go for a yearly renewal. So, we end up talking to people from Morphisec once a year, but it is usually at renewal time."

"The only problem is that their support lives in Israel, so the time zones are a bit off, but I've never had any complaint beyond that."

"It might be a bit much to ask, but we are now beginning to use Morphisec Scout, which provides vulnerability information. At this time, it's recognizing vulnerabilities and reporting them to us, but it's not necessarily resolving them. There's still a separate manual process to resolve those vulnerabilities, primarily through upgrades. We have to do that outside of Morphisec. If Morphisec could somehow have that capability built into it, that would be very effective."

"Some of the filters for the console need improvement. There are alerts that show up and just being able to acknowledge that we've seen those and not turn them off, but dismiss them, would be a huge benefit."

"Sometimes it generates false positive alerts. They need to continue working on that. They have provided solutions for it and have fixed issues with updated versions. The service is quite good but they need to work on it more so that there are no false positive alerts."

More Morphisec cons

Pricing and Cost Advice

"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."

"The product is very expensive."

"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."

"I know that the product is incredibly expensive."

"I was working in the government and it was too expensive for us to use our Microsoft products."

"The pricing is normal. Considering its popularity, it's not overpriced."

"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."

"It is much more expensive than using another solution because we have had to include some options and upgrade our license."

More Microsoft Defender for Office 365 pricing and cost advice

"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."

"It does not have multi-tenants. If South Africa wants to show only the machines that they have, they need their own cloud incidence. It is not possible to have that in a single cloud incidence with multiple tenants in it, instead you need to have multiple cloud incidences. Then, if you have that, it will be more expensive. However, they are going to change that, which is good."

"Our licensing is tied into our contract. Because we have a long-term contract, our pricing is a little bit lower. It is per year, so we don't get charged per endpoint, but we do have a cap. Our cap is 80 endpoints. If we were to go over 80, when we renewed our contract, which is not until three years are over. Then, they would reevaluate, and say, "Well, you have more than 80 devices active right now. This is going to be the price change." They know that we are installing and replacing computers, so the numbers will be all over the place depending on whether you archive or don't archive, which is the reason why we just have to keep up on that stuff."

"We are still using a separate tool. I know for our 600 or I think we're actually licensed for up to 700 users, it runs me 23 or $24,000 a year. When you're talking to that many users plus servers being protected, that's well worth the investment for that dollar amount."

"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."

"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."

"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."

"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."

More Morphisec pricing and cost advice

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Top Industries

By visitors reading reviews

Computer Software Company

12%

Manufacturing Company

Financial Services Firm

Comms Service Provider

Outsourcing Company

16%

Manufacturing Company

13%

Construction Company

11%

Financial Services Firm

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	24
Midsize Enterprise	11
Large Enterprise	32

By reviewers
Company Size	Count
Small Business	5
Midsize Enterprise	8
Large Enterprise	8

Questions from the Community

What is your experience regarding pricing and costs for Microsoft Defender for Office 365?

My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as a standalone product. It's very competitive compared to what competitors are ch...

See all answers

What needs improvement with Microsoft Defender for Office 365?

I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware. We are seeing a lot more malware-less emails that Defender for Offi...

See all answers

What is your primary use case for Microsoft Defender for Office 365?

My main use cases for Microsoft Defender for Office 365 include email hygiene.

See all answers

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Comparisons

Proofpoint Email Protection vs Microsoft Defender for Office 365

Compared 6% of the time

Mimecast Advanced Email Security vs Microsoft Defender for Office 365

Compared 5% of the time

Check Point Email Security (formerly Harmony Email & Collaboration) vs Microsoft Defender for Office 365

Compared 5% of the time

Cisco Secure Email vs Microsoft Defender for Office 365

Compared 3% of the time

Barracuda Email Protection vs Microsoft Defender for Office 365

Compared 3% of the time

More Microsoft Defender for Office 365 Competitors

Symantec Endpoint Security vs Morphisec

Compared 7% of the time

CrowdStrike Falcon vs Morphisec

Compared 5% of the time

FortiCNAPP vs Morphisec

Compared 5% of the time

Halcyon vs Morphisec

Compared 4% of the time

SentinelOne Singularity Endpoint vs Morphisec

Compared 4% of the time

More Morphisec Competitors

Product Reports

Microsoft Defender for Office 365

Download Microsoft Defender for Office 365 product report

Microsoft Defender for Office 365 report

Download Morphisec product report

Also Known As

MS Defender for Office 365

Morphisec, Morphisec Moving Target Defense

Overview

Microsoft Defender for Office 365 offers real-time email security, enhancing threat detection through integration within the Microsoft ecosystem. Its user-friendly interface and central management streamline operations, providing robust protection against phishing, ransomware, and malware.

Defender for Office 365 is focused on efficiently securing email communication by safeguarding against phishing, malware, and spam threats. With its strong integration with other Microsoft services, it is tailored to improve endpoint security and identity protection. Its centralized management tools simplify threat prioritization, while the automated threat response capabilities ensure swift actions against potential risks. Organizations leverage its capabilities to efficiently manage their cybersecurity efforts, particularly in remote work environments, while maintaining a secure system across Office 365 applications and Azure-hosted services.

What are the key features?

Real-time Email Protection: Continuously monitors and protects email communications.
Safe Attachments and Links: Scans attachments and links for potential threats.
Anti-Phishing Measures: Provides tools to detect and block phishing attempts.
Integration with Microsoft Services: Seamlessly connects with other Microsoft applications for enhanced security.
Automated Threat Responses: Activates immediate responses to detected threats.

What benefits should users expect from reviews?

Time Savings: Automates processes to reduce manual threat management efforts.
Improved Cybersecurity: Strengthens organizational defenses against various cyber threats.
Efficient Remote Work: Enhances protection for remote teams and virtual collaborations.
Comprehensive Coverage: Extends protection across Office 365 and Azure services.

Implementations of Defender for Office 365 vary across industries, optimizing email security for sectors such as finance, healthcare, and education. In finance, it aids in protecting sensitive financial data from phishing and fraud. Healthcare benefits from secure communications, ensuring patient data privacy. Educational institutions use it to maintain secure virtual learning environments against cyber threats.

Microsoft

Morphisec enhances security with its signatureless attack prevention, integrating smoothly with Microsoft Defender. Users benefit from real-time threat detection and seamless system integration, protecting against zero-day threats and ransomware across networks.

Morphisec's security solution focuses on preventing cyber threats without requiring threat signatures or user action. Its integration with Microsoft Defender offers simplified visibility and management while delivering quick responses. Lightweight in nature, Morphisec ensures zero performance degradation and employs in-memory protection along with Moving Target Defense. This approach effectively counters zero-day threats and ransomware, maintaining a user-centric dashboard that eases administrative workloads. Morphisec's easy deployment also enables small teams to manage risks and uphold robust security measures efficiently.

What are Morphisec's key features?

Signatureless Threat Prevention: Stops attacks without threat signatures or user interaction.
Microsoft Defender Integration: Provides unified management and quick response capabilities.
In-Memory Protection: Shields against zero-day and ransomware threats efficiently.
Moving Target Defense: Minimizes exposure to in-memory attacks.
User-Friendly Dashboard: Simplifies administration by reducing burdens.
Easy Deployment: Facilitates straightforward setup for small teams.

What benefits and ROI should be considered in user reviews?

Real-Time Detection: Immediate identification of threats enhances proactive threat management.
Seamless Integration: Compatible with existing systems, reducing delay risks.
Cloud-Based Updates: Ensures current protection with minimal manual input.
Multi-Layered Security: Adds a solid last defense layer, supplementing other antivirus solutions.

Morphisec is widely used across industries like financial services, healthcare, and manufacturing to bolster defenses against malware and ransomware. Its deployment spans workstations and servers, integrating efficiently into existing infrastructures. Industries value real-time threat detection, ease of deployment, and cloud-based updates, noting its ability to identify threats missed by other antivirus solutions.

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.

Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center

Microsoft Defender for Office 365 vs. Morphisec