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Microsoft Defender for Office 365 vs Morphisec comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
3rd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Email Security (2nd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (2nd)
Morphisec
Ranking in Advanced Threat Protection (ATP)
29th
Average Rating
9.2
Reviews Sentiment
7.4
Number of Reviews
21
Ranking in other categories
Vulnerability Management (58th), Endpoint Protection Platform (EPP) (47th), Endpoint Detection and Response (EDR) (61st), Cloud Workload Protection Platforms (CWPP) (36th), Threat Deception Platforms (13th)
 

Mindshare comparison

As of August 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 6.4%, down from 13.7% compared to the previous year. The mindshare of Morphisec is 2.2%, up from 0.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.4%
Morphisec2.2%
Other91.4%
Advanced Threat Protection (ATP)
 

Featured Reviews

Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
Rick Schibler - PeerSpot reviewer
VP of Information Technology at Kentucky Trailer
Offers in-memory protection at a lower price than competitors
Morphisec's in-memory protection is probably the most valuable feature because it stops malicious activity from occurring. If something tries to install or act as a sleeper agent, Morphisec will detect and stop it. Morphisec's Moving Target Defense is critical to hardening our attack surface. If it detects something, it indicates whether it's valid. That means you've got a breach requiring investigation. It detects anomalies but doesn't necessarily point to what caused them. You still need to do that work. The solution is reasonably easy to administer. They made some changes last year, adding a cloud-based monitoring solution that makes deploying and monitoring our endpoints easy.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The deployment capability is a great feature, and we're able to activate this feature throughout France with a click."
"Does a thorough job of examining email and URLs for malicious content."
"The two main features that prove most beneficial for us are URL scanning and attachment scanning."
"The most valuable feature is protection against malicious links, fishing, and impersonation. You can train people to be aware of these threats, but they're not always careful. When they're using their phones between meetings, they click on a link, and it's game over."
"It definitely is a must for email protection and O365 app DLP, and combined with Microsoft Defender for Endpoint, Microsoft Defender for Identity, and MCAS, it provides a holistic solution for threat protection, email protection, O365 apps protection, and DLP for both internal and external risks."
"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"Overall, I would rate Microsoft Defender for Office 365 at a ten."
"The ability to respond to threats if very important."
"Morphisec has enabled us to become a lot less paranoid when it comes to staff clicking on things or accessing things that they shouldn't that could infect the whole system. Our original ransomware attack that happened came from someone's Google drive and then just filtered on through that. It has put our minds at ease a lot more in running it. It's also another layer of security that has been proven to be effective for us."
"The biggest feature is that it hides everything from your operating system that's running in-memory from anything to try to run against it. That's the most unique thing that's on the market. There's nothing else out there that's quite like that. That's a big selling point and why we went with it. It does exactly what the design does. If you can't find it, you can't execute against it."
"Morphisec gives me even more than Microsoft can give me, even if I were to pay."
"The fact that Morphisec uses deterministic attack prevention that does not require human intervention has affected our security team's operations by making things much simpler. We don't have to really track down various alerts anymore, they've just stopped. At that point, we can go in and we can clean up whatever needs to be cleaned up. There are some things that Morphisec detects that we can't really remove, it's parts of Internet Explorer, but it's being blocked anyway. So we're happy with that."
"We have not had one machine that has been taken down due to malware now in almost four and a half years, with 600 machines that we don't have routine infections on because nothing can execute."
"If you have the ability to get Morphisec into their environment, it's going to be a hundred percent return on investment."
"With Morphisec, at least when it does happen, I feel confident that we have in place solutions that will not only prevent it, but also let us know when something has happened."
"Since using Morphisec we have seen a downturn in attacks because Morphisec protects us versus Defenders and whatnot that are signature-based. I know we have not had any issues with ransomware or other zero-day attacks that we've seen with machines that, all of a sudden, have become before we instituted the product. Now the machine had to be re-imaged and there was a loss of data because something was on the machine. You couldn't really determine what was on the machine because nothing was picking it up. The products we were using weren't picking it up."
 

Cons

"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"To improve Microsoft Defender for Office 365, it would be nice to have more accessibility for users to see on their end what they are doing that could cause a threat."
"In the areas of improvement for Microsoft Defender for Office 365, the console is the biggest challenge for me."
"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"The only thing they should improve is the licensing model. They should stop changing it. A year ago, the five features I mentioned were included in one product. Now, three of them are bundled into one product, and you have to pay extra for the other two. I don't mind paying extra, but I don't want them to change it every year or every six months. I need to know what I'm looking at and not worry about it next year."
"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"The custom alerts have to improve a lot."
"I haven't seen ROI because I haven't seen a threat that it has protected against, exactly."
"I haven't been able to get the cloud deployment to work."
"The dashboard is the area that requires the most improvement."
"It would be useful for them if they had some kind of network discovery."
"Morphisec is a venture startup. They are still early in their growth stage. They need to get mature on their customer support and on how they interface with system tools. For example, they need to get multifactor in place and an API for the major multi-factor systems, e.g., Okta, Duo, Ping, and Microsoft. They don't have them built in yet. They are working on them. It is just not there yet. Also, their stability, customer support, and processes need improvement, which is just part of maturity."
"Some of the filters for the console need improvement. There are alerts that show up and just being able to acknowledge that we've seen those and not turn them off, but dismiss them, would be a huge benefit."
"We have only had four attacks in the last year, "attacks" being some benign PDF from a vendor that, for some reason, were triggered. There were no actual attacks. They were just four false positives, or something lowly like adware. There have been false positives with both the on-premises solution and the cloud solution."
"If anything, tech support might be their weakest link. The process of getting someone involved sometimes takes a little time. It seems to me that they should have all the data they need to let me know whether an alert is legitimate or not, but they tend to need a lot of information from me to get to the bottom of something. It usually takes a little longer than I would expect."
 

Pricing and Cost Advice

"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"The product is very expensive."
"The pricing is normal. Considering its popularity, it's not overpriced."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"It is an annual subscription basis per device. For the devices that we have in scope right now, it is about $25,000 a year."
"Price-wise, it's on the higher side. A traditional antivirus solution is cheaper, but in terms of security and manageability, its ROI is better than a traditional antivirus. I would recommend it to anybody evaluating or considering an antivirus solution. If your system gets compromised, the cost of ransom would be a lot more. This way, it saves a lot of cost."
"It is priced correctly for what it does. They end up doing a good deal of discounting, but I think it is priced appropriately."
"Compared to their competitors, the price of Morphisec is not that high. You can easily deploy it on a large-scale or small-scale network."
"It is a little bit more expensive than other security products that we use, but it does provide us good protection. So, it is a trade-off."
"The pricing is definitely fair for what it does."
"Licenses are per endpoint, and that's true for the cloud version as well. The only difference is that there is a little extra charge for the cloud version."
"Morphisec is reasonably priced because our parent company's other subsidiaries use different products like CrowdStrike. CrowdStrike is four or five times more expensive than Morphisec. The competitive pricing saves us money in our overall security stack."
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Top Industries

By visitors reading reviews
Computer Software Company
11%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Outsourcing Company
19%
Manufacturing Company
12%
Construction Company
12%
Financial Services Firm
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
By reviewers
Company SizeCount
Small Business5
Midsize Enterprise8
Large Enterprise8
 

Questions from the Community

What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as a standalone product. It's very competitive compared to what competitors are ch...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware. We are seeing a lot more malware-less emails that Defender for Offi...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
Ask a question
Earn 20 points
 

Also Known As

MS Defender for Office 365
Morphisec, Morphisec Moving Target Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Lenovo/Motorola, TruGreen, Covenant Health, Citizens Medical Center
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Morphisec and other solutions. Updated: June 2026.
908,800 professionals have used our research since 2012.