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Cisco Secure Email vs Microsoft Defender for Office 365 comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (22nd), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (12th), Bot Management (3rd), ZTNA as a Service (8th), ZTNA (4th), Secure Access Service Edge (SASE) (9th), Remote Browser Isolation (RBI) (2nd)
Cisco Secure Email
Ranking in Email Security
6th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (9th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (3rd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of August 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.4% compared to the previous year. The mindshare of Cisco Secure Email is 4.4%, down from 5.5% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 5.7%, down from 11.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3655.7%
Cisco Secure Email4.4%
Cloudflare One1.7%
Other88.2%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cloudflare is by far the most effective solution that I have come across."
"Cloudflare is simple to use."
"Cloudflare Access is a stable solution."
"Enables me to work from two locations."
"It is a stable solution."
"The simplicity of the solution is its valuable features as almost no effort was needed to learn the configurations. It is also one of the cheapest firewalls available in this category."
"I'm very satisfied with the environment and the dashboard."
"The solution has different options that can be used to differentiate DDoS attacks."
"The logs are easily readable and help diagnose problems, although they can be difficult to find initially. The solution addresses our email security, but for the rest of our security, we would use multiple vendors. It covers everything through email, like antivirus, IDS, and IPS."
"The added value of it is that every migration to a new version is initiated by the Cisco version itself, so that is a bunch of work that you don't have to do on the Cisco ESA system on-premise. As it becomes a safe platform, you don't need to invest anything in your own data center or in your upgrade path."
"It is a user-friendly product."
"I love the Advanced Malware Protection feature. It works very well... The appliance has more security such as SDF, DKIM, DMARC, and encryption."
"Email service is one of the services that we offer at Galaxy, and Cisco ESA has improved our business so much that our customers want to maintain their business with us for email security, with over 500 domains on our email platform and improved profitability in everything."
"The most valuable features are Advanced Malware Protection, URL filtering, and of course Reputation Filtering."
"It has an intuitive, clear graphical interface where you can deploy your policies and understand the overall flow. There are a lot of things that you cannot handle on the graphic interface, like message filters. For this, you need to go to a lower level where you have more power, like command line interface. So, this solution has the best of both worlds. There are not a lot of bells and whistles. It is more practical with access to most features that you can configure."
"It saves a lot of time wasting, for example, phishing attacks distract a user's attention and forged emails waste a lot of time, and this solution helps protect user data."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"The deployment capability is a great feature."
"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
"Microsoft Defender has a feature to protect each and every attachment. Even if it's an encrypted attachment, it will check for any potential threats."
"The initial setup was easy."
"There are several features that I consider valuable."
"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."
"It also gives me good visibility because, with Defender, I'm using a Microsoft product to defend Microsoft products. The integration was really seamless and I have wide visibility because it picks up almost everything. Literally, I can see almost every activity that happens, from the e-mail to the workstation itself."
 

Cons

"I would like them to include a VPN feature to provide a secure connection to the data center."
"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"Operating and tuning the product is difficult."
"The response time for support must be reduced."
"Feedback could be enhanced."
"Cloudflare DDoS has poor technical support."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"The user interface of the Email Security Gateway should be improved."
"Don't neglect that because if you just try to rely on Cisco support you're going to notice pretty consistent slowdowns."
"The interface is dated. It has looked pretty much the same for 15 years or so. It would be helpful to be able to do everything from one spot. The centralized quarantine and reporting are completely separate from policy administration."
"The primary areas for improvement are the pricing and the complexity of deployment."
"There could be additional DLP functionality for it."
"If you are not a technical guy, it is hard to maneuver, but as soon as you work on it, it gets better and better. If there was a better way to know how to do things or how to find things, it would be good."
"I would rate the stability a six out of ten. We had multiple issues with the stability."
"I would like more functionality and how to use it for Level 2 type staff. The biggest issue is it needs to be easier to use and navigate."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"The cost of Security Copilot is up there right now, and I think it needs to come down for more people to adopt."
"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"There's room for improvement regarding the time frame for retrieving emails."
"This is quite an expensive solution and understanding the pricing model and features is quite complicated and it can, in fact, be a nightmare when dealing with Microsoft."
"From a development point of view, if I wanted to do development on my actual machine where Defender is, the organization can set certain policies or Defender makes that prohibitive."
"The XDR dashboard has room for improvement."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
 

Pricing and Cost Advice

"The prices are slightly expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"The solution is not that expensive."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The solution's pricing lacks transparency."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The price is significantly high."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"It is a super big router that costs a few hundred thousand dollars."
"The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recommendations, not buying decisions."
"The licensing was all transferred."
"In addition to the standard licensing, there is a cost for SMARTnet as well."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"It is not that costly. We pay for the solution through a contractor and pay an annual fee."
"It's a user-base subscription."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is very expensive."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
11%
Outsourcing Company
9%
Financial Services Firm
8%
Financial Services Firm
12%
Manufacturing Company
9%
Outsourcing Company
7%
Computer Software Company
7%
Computer Software Company
11%
Manufacturing Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise27
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise11
Large Enterprise32
 

Questions from the Community

What needs improvement with Cloudflare Zero Trust Platform?
In my opinion, Cloudflare One can be improved mainly through compatibility, as the integration should be much simpler...
What is your primary use case for Cloudflare Zero Trust Platform?
Cloudflare One's primary use case for my organization is to protect servers and to provide remote access with the VPN...
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your primary use case for Cisco Secure Email?
We are using Cisco Secure Email to monitor the outgoing and incoming mail traffic in our financial institute. We have...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: August 2026.
908,834 professionals have used our research since 2012.