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Cisco Secure Email vs Proofpoint Email Protection comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jan 12, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.4
Users found Microsoft Defender for Office 365 cost-effective, citing improved protection, time efficiency, and savings in security management.
Sentiment score
6.7
Cisco Secure Email enhances security, reduces costs, and boosts productivity, providing ROI similar to preventive insurance against breaches.
Sentiment score
7.0
Proofpoint Email Protection effectively reduced phishing threats, provided financial benefits, and received positive feedback for its cost savings.
It has also decreased our time to detection and response by about 15 to 20 percent.
 

Customer Service

Sentiment score
6.9
Microsoft Defender for Office 365 offers knowledgeable support, though escalation delays and outdated documentation can affect resolution speed.
Sentiment score
7.3
Cisco Secure Email is praised for its knowledgeable, proactive support with quick resolutions, despite occasional delays for some users.
Sentiment score
7.3
Proofpoint Email Protection's customer service is responsive and professional, though global availability and portal access could be improved.
Customer service and support have been fantastic.
Cisco's tech support can be hit or miss, depending on the engineer you get.
The support is pretty decent, with a rating of eight out of ten.
 

Scalability Issues

Sentiment score
8.1
Microsoft Defender for Office 365 is scalable, adaptable, and integrates seamlessly, supporting medium to large enterprises efficiently.
Sentiment score
7.4
Cisco Secure Email excels in scalability, supporting large enterprises seamlessly, with minor hardware challenges noted by some users.
Sentiment score
7.6
Proofpoint Email Protection is praised for its scalability and adaptability, effectively supporting large enterprises with its cloud-based architecture.
The on-premises hardware is not very scalable, but switching to the SaaS offering is expected to improve scalability.
Proofpoint is scalable for multi-site organizations with thousands of users.
 

Stability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 is highly rated for stability, featuring strong performance and rare minor network issues.
Sentiment score
8.1
Cisco Secure Email is praised for reliability, stability, and efficiency, outperforming rivals with minimal issues and high user ratings.
Sentiment score
8.1
Proofpoint Email Protection is praised for its reliability, with minimal disruptions and occasional concerns related to its recent sale.
Based on my experience, the stability of Cisco Secure Email is very strong.
 

Room For Improvement

Microsoft Defender for Office 365 requires improvements in antivirus, scalability, integration, interface, threat intelligence, and licensing transparency.
Cisco Secure Email needs UI improvements, simplified pricing and deployment, enhanced features, and streamlined management for better user experience.
Proofpoint Email Protection needs enhanced integration, improved functionality and support, better UI, lower pricing, and additional security features.
The main area for improvement is simplifying the implementation and rollout process.
I would reduce the cost.
The solution should better analyze the actual content rather than only focusing on the email header or origin.
It would be beneficial to have the functionality of the Email Threat Defense integrated into the Email Security Gateway so customers don't have to buy two products for full email protection.
More security could be implemented.
Proofpoint could expand its phishing detection capabilities to improve its efficiency.
 

Setup Cost

Microsoft Defender for Office 365 pricing varies; often costly for SMBs but competitive for enterprises, with added licensing complexities.
Cisco Secure Email offers robust features and value, with prices varying based on services, usage, and licensing complexity.
Proofpoint Email Protection is costly but valued for its robust security features, with clear pricing at $8 per user.
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Its cost is bundled with other Cisco products.
The licensing is a mess and needs sorting out.
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
Customers pay around $90,000 yearly for a 1,000-user organization, with the subscription license being the main expense, apart from implementation fees.
Additional costs do come in, but it enhances security.
 

Valuable Features

Microsoft Defender for Office 365 provides comprehensive email protection with seamless Microsoft integration, enhancing threat management and data security.
Cisco Secure Email offers strong spam and malware protection, seamless Active Directory integration, and customizable security features for effective threat management.
Proofpoint Email Protection excels in anti-phishing, spam blocking, integration with Office 365, and advanced threat detection using AI.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
Microsoft Defender for Office 365 is now part of a centralized tenant for my entire group.
It also possesses multiple modules for spam detection, malware detection, and threat intelligence, which are valuable in categorizing emails and determining actions.
It is highly effective in catching phishing and spam emails.
It covers everything through email, like antivirus, IDS, and IPS.
The main feature I find most effective is that Proofpoint Email Protection scans emails and quarantines the doubtful ones.
 

Categories and Ranking

Microsoft Defender for Offi...
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Ranking in Email Security
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
48
Ranking in other categories
Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th)
Cisco Secure Email
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
62
Ranking in other categories
Cisco Security Portfolio (8th)
Proofpoint Email Protection
Ranking in Email Security
3rd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
51
Ranking in other categories
Security Awareness Training (2nd), Digital Risk Protection (3rd), Office 365 Protection (1st), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of April 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 13.1%, down from 19.0% compared to the previous year. The mindshare of Cisco Secure Email is 6.7%, down from 8.7% compared to the previous year. The mindshare of Proofpoint Email Protection is 8.1%, down from 12.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Kostas Karidas - PeerSpot reviewer
Helps prevent security breaches but fails to improve in the area of AI
I have not noticed any impressive advanced threat protection mechanisms in the tool. I don't know if there are any AI features in the product. I don't know if there is any other technology embedded in the solution. Cisco Secure Email successfully mitigated potential email threats. My company has seen plenty of scenarios where Cisco Secure Email successfully mitigated potential email threats, spam emails, and fraudulent domains. The product is good for dealing with spam emails, and it can take care of more than 100 spam emails per day. A huge number of spam emails are monitored with the help of Cisco Secure Email. I would not recommend the product to other businesses because you need to have some kind of expertise in configuring and knowing a bit about the tool's GUI. The tool also lacks in the area of AI mechanics. If I would like to have an overview and review another solution, I would go for another product other than Cisco Secure Email. I can definitely suggest others to look at the product and review it, but I would also recommend that they compare it with the other solutions in the market. I wouldn't prioritize Cisco Secure Email over other tools. Either the support partner of the product or I take care of the tool's maintenance phase by looking into the configurations and doing some fine-tuning. I rate the tool a seven to eight out of ten.
AhmedRamadan - PeerSpot reviewer
Optimize email security with effective sandboxing and auto Pull for quarantine
Proofpoint is used as an email security gateway for big enterprises, primarily for their on-premises servers. Many customers also use it alongside Office 365 Proofpoint offers a complete solution for email security with features like DLP, email archiving, and encryption. The most valuable…
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845,040 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Educational Organization
34%
Computer Software Company
16%
Financial Services Firm
7%
Manufacturing Company
4%
Educational Organization
30%
Computer Software Company
11%
Financial Services Firm
8%
Manufacturing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
I don't have detailed specifics on pricing, setup cost, or licensing.
What needs improvement with Microsoft Defender for Office 365?
I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost.
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The licensing is a mess and needs sorting out. I am not really concerned about the pricing because I only make recomm...
What needs improvement with Cisco Secure Email?
The user interface needs massive improvement. While the device works fine and it's not complicated to write policies,...
What is your experience regarding pricing and costs for Proofpoint Email Protection?
In terms of pricing, it is okay compared to others. I would say it is normal. Additional costs do come in, but it enh...
What needs improvement with Proofpoint Email Protection?
In terms of improvement, the price could be better. Additionally, more security could be implemented.
 

Also Known As

MS Defender for Office 365
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
Proofpoint Enterprise Protection, Cofense PhishMe, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Cisco Secure Email vs. Proofpoint Email Protection and other solutions. Updated: March 2025.
845,040 professionals have used our research since 2012.