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Microsoft Defender XDR vs ReliaQuest GreyMatter comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
112
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Endpoint Detection and Response (EDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Extended Detection and Response (XDR)
5th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Endpoint Detection and Response (EDR) (8th), Microsoft Security Suite (4th)
ReliaQuest GreyMatter
Ranking in Extended Detection and Response (XDR)
25th
Average Rating
9.6
Reviews Sentiment
8.1
Number of Reviews
2
Ranking in other categories
Digital Risk Protection (11th), Managed Detection and Response (MDR) (18th)
 

Mindshare comparison

As of June 2026, in the Extended Detection and Response (XDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 4.6%, down from 5.1% compared to the previous year. The mindshare of Microsoft Defender XDR is 4.2%, down from 5.9% compared to the previous year. The mindshare of ReliaQuest GreyMatter is 0.9%, up from 0.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Extended Detection and Response (XDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks4.6%
Microsoft Defender XDR4.2%
ReliaQuest GreyMatter0.9%
Other90.3%
Extended Detection and Response (XDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
Zaid bin junaid  - PeerSpot reviewer
Product Manager at Flash
Improved threat detection has reduced incidents and has automated investigations with AI
There are multiple features of ReliaQuest GreyMatter which I love personally. The agentic AI, which helps in autonomous investigation and containment, is multiplying the speed of the task to be done. Features such as managed service integration and MDR with human expertise when needed are some major features which I love about ReliaQuest GreyMatter.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution allows us to make investigations. Other XDR solutions also provide similar capabilities but for investigation, Cortex XDR is better."
"I recommend this solution to others because it is easy to manage, reliable, and overall good to use."
"The product has an intuitive dashboard."
"The anti-exploit is impenetrable."
"It can automatically correlate events and logs, which is very helpful for an IT administrator. It can correlate different kinds of malware activities over a network, agent, or host system. You do not need to do it manually. It is a good feature. It is also a user-friendly solution. We have deployed it on the cloud because our space does not provide any flexibility for on-premises deployment, but Palo Alto has added some flexibility to install it on-premises. It must be like the same Cortex XDR agent for all the VPN services, web filtering services, and everything else."
"Their XDR agent and their behavioral indicators of compromise (BIOC) are pretty nice. Their managed threat hunting is also pretty nice. They also have WildFire, which is a service for actively looking for malware. It's quite useful."
"Cortex XDR by Palo Alto Networks has helped lighten the load of our security analysts because it was the major tool that we were using and the one we utilized most."
"The good thing about the product is that it's always scanning."
"It reduces the risk of users accidentally clicking on phishing emails."
"Many people don't realize that Microsoft Azure, Exchange Online, and the security and compliance portal all sync together. For instance, within the Azure portal you can set security restrictions and policies to help secure your tenants... The good part of it is that these products have already been integrated. When you sign on as an admin you have global admin rights and that gives you access to all these features."
"I like that it's stable. It's been stable for a long time, and Microsoft Defender has done a good job there."
"We also use Microsoft Sentinel, Defender for Cloud, Defender for Identity, and Microsoft Defender for Cloud Apps. They are all integrated and it was very easy to integrate them. In my experience with the integrations, it was just a click of a button and things were integrated. It's just a button."
"Scanning, vulnerability reporting, and the dashboard are the most valuable features."
"In our company,we have faced multiple attacks over the last few months, but none of them have been successful, and I think Microsoft Defender XDR has played a major role in it."
"Microsoft 365 Defender is a good solution and easy to use."
"The ability to hunt that IM data set or the identity data set at the same time is valuable. As incident response professionals, we are very used to EDRs and having device process registry telemetry, but a lot of times, we do not have that identity data right there with us, so we have to go search for it in some other silo. Being able to cross-correlate via both datasets at the same time is something that we can only do in Def"
"ReliaQuest GreyMatter saves around 60% of time or resources."
"ReliaQuest GreyMatter has helped us to reduce security incidents by 89%, which is a significant amount of incidents we have seen."
 

Cons

"It would be good to have a better way to search for a file within the UI."
"A little bit more automation would be nice."
"We have found that there are times Cortex XDR by Palo Alto Networks does not detect some of the viruses, we have to use another protection solution called Kaspersky."
"There are some default policies which sometimes affect our applications and cause them to run around."
"If you compare it to SentinelOne, which has more functionalities and detection capabilities on an open platform, the pricing on SentinelOne is far more reasonable and cheaper than Cortex XDR by Palo Alto Networks."
"I think sometimes Cortex XDR agent automatically stops event capturing from the device, and then even the dashboard does not get any notifications from the agent."
"Palo Alto Networks Cortex XDR does not detect malicious activity like in other anti-virus solutions like Trend Micro and Windows with Cisco."
"The solution eats memory of the computer, unlike anything I've ever seen."
"The onboarding and offboarding need improvement. I work with other vendors as well, and they have an option to add a device or remove a device from the portal, whereas with Microsoft 365 Defender, we need to do that manually. However, once you do that, everything can be controlled through the portal, but getting the device onboarded and offboarded is currently manual. If we have an option to simply remove a device from the portal or get a device added from the portal, it would be more convenient. The rest of the features are similar. This is the only area where I found it different from others. I would also like to be able to simply filter with a few of the queries that are already there."
"The advanced threat-hunting capabilities are phenomenal, and the security copilot enhances that, but some data elements could be better or have more context inside of the advanced tables themselves. The schemas feel a little limited to what they're building into the product. It's probably just a maturity thing. I imagine we'll see the features I want in the next year."
"The data recovery and backup could be improved."
"When we do investigations, it would be better if Microsoft could populate the host dashboard more. When we open any host for investigation, we want the entire timeline of what is happening on the host, including all the users logging in, their hardware, Windows version, etc."
"These days, in the security industry, there is a buzzword called zero trust. I personally have not seen much evidence of how Defender can enhance the story of Zero Trust for enterprises."
"The automation response being slow is the main concern; when an incident occurs or if I run a remediation, it takes significant time to complete the remediation."
"Intrusion detection and prevention would be great to have with 365 Defender."
"Since all of our databases are updated and located in the cloud, I would like additional support for this."
"Areas that have room for improvement include user interface and integration."
 

Pricing and Cost Advice

"In terms of the cost Cortex XDR by Palo Alto Networks is very expensive because we are a Mexican company and when you translate dollars to pesos the cost is very high. The solution is very expensive for Mexican companies. I understand that they have international prices, but I do not think it offsets the price enough for many companies in countries, such as Mexico. The amount it is reduced is not a massive percentage."
"Our customers have expressed that the price is high."
"The price of the solution could be reduced. I have customers that have voiced that the solution is good for the value but if I want to sell more of the solution the price reduction would help."
"Cortex XDR’s pricing is very reasonable."
"It is "expensive" and flexible."
"I did PoCs on products called Cylance and CrowdStrike. Although, I consider these products and they were also good, when it come to cost and budgetary factors, Traps has been proven to be better than the other two products. It is quite cost-effective and delivers all the entire solution which we require."
"The price is on the higher side, but it's okay."
"The solution has one subscription for endpoint protection and one subscription for detection and response. The two licenses combined give you the BRO version."
"The most valuable licensing option is expensive, so pricing could be improved. Licensing options for this solution also need to be consolidated, because they frequently change."
"The price could be better. Normally, the costs depend on the country you're located in for the license. When we were in the initial stage, we went with the E5 license they call premium standard. It cost us around $5.20 per month for four users."
"Microsoft 365 Defender offers competitive pricing."
"I would like to have more security features in the lower licenses because not every customer is able to buy E5 licenses. The bundling isn't always easy for our customers to understand. Compared to other tools, it's a good price."
"The bundling of software makes it easier to manage our setup, but Microsoft purposefully obfuscates this through marketing ploys to hide costs."
"Its licensing and pricing are handled by someone else. My role is limited to incidents or issues with the portal, but you get what you pay for. It is worth the cost."
"Defender plan 1 is tenant-wise, and Defender plan 2 is per-user, which makes it more expensive. To have certain features, you would need to purchase the E5 license. For all of the capabilities that the tool provides, the price, though it can be high, is fair."
"Microsoft purposely makes its license combinations complex and includes combinations like Microsoft 365 E3 and Microsoft 365 E5, Office 365 E3, Office 365 E5, and Office 365 E1, so you get confused. Microsoft tries to sell you a bundle of a lot of things together."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
10%
Comms Service Provider
9%
Computer Software Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Manufacturing Company
7%
Financial Services Firm
11%
Manufacturing Company
9%
Construction Company
7%
Retailer
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise20
Large Enterprise52
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
What needs improvement with ReliaQuest GreyMatter?
Areas that have room for improvement include user interface and integration.
What is your primary use case for ReliaQuest GreyMatter?
I use ReliaQuest GreyMatter for detection and response, XDR, and SIEM. The best features I like about GreyMatter the ...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Information Not Available
Find out what your peers are saying about Microsoft Defender XDR vs. ReliaQuest GreyMatter and other solutions. Updated: April 2026.
900,747 professionals have used our research since 2012.