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Microsoft Defender XDR vs ReliaQuest GreyMatter comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
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Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
112
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Endpoint Detection and Response (EDR) (6th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Extended Detection and Response (XDR)
5th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Endpoint Detection and Response (EDR) (8th), Microsoft Security Suite (4th)
ReliaQuest GreyMatter
Ranking in Extended Detection and Response (XDR)
25th
Average Rating
9.6
Reviews Sentiment
8.1
Number of Reviews
2
Ranking in other categories
Digital Risk Protection (11th), Managed Detection and Response (MDR) (18th)
 

Mindshare comparison

As of June 2026, in the Extended Detection and Response (XDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 4.6%, down from 5.1% compared to the previous year. The mindshare of Microsoft Defender XDR is 4.2%, down from 5.9% compared to the previous year. The mindshare of ReliaQuest GreyMatter is 0.9%, up from 0.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Extended Detection and Response (XDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks4.6%
Microsoft Defender XDR4.2%
ReliaQuest GreyMatter0.9%
Other90.3%
Extended Detection and Response (XDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
Zaid bin junaid  - PeerSpot reviewer
Product Manager at Flash
Improved threat detection has reduced incidents and has automated investigations with AI
There are multiple features of ReliaQuest GreyMatter which I love personally. The agentic AI, which helps in autonomous investigation and containment, is multiplying the speed of the task to be done. Features such as managed service integration and MDR with human expertise when needed are some major features which I love about ReliaQuest GreyMatter.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution allows us to make investigations. Other XDR solutions also provide similar capabilities but for investigation, Cortex XDR is better."
"Palo Alto is constantly adding new features."
"We switched because there were a lot of added features with Palo Alto that Check Point didn't have, and it was an upgrade for us."
"Being a cloud solution it is very flexible in serving internal and external connections and a broad range of devices."
"The anti-exploit is impenetrable. We chose Traps because it is the only product that we were not able to get anything past."
"We can visualize and control the activities in the environment from anywhere."
"When the pandemic started, Palo Alto came up with many solutions, which helped with the quick shift from on-premises to the cloud."
"Cortex is the best tool for endpoint detection, and I have used it to verify hashes or domains to identify malicious activity, trigger playbooks that automate and gather endpoint logs, block malicious processes, and update incident tickets, showcasing end-to-end processes with automation in investigation and reducing the analysis workflow."
"The incident-level visibility across the cyber attack chain when using Microsoft Defender XDR is great."
"The most valuable feature is probably the aggregation and correlation of the different telemetry points with Defender for Identity, Defender for Endpoint, and Defender for Cloud Apps. All of these various things are part of that portal. We've wanted that single pane of glass for years."
"Microsoft Defender XDR has significantly improved our operational security."
"We are able to consolidate licences and make use of many Microsoft products using this solution, and if we have any Microsoft customers, we encourage them to use this solution for enterprise defence."
"Scanning, vulnerability reporting, and the dashboard are the most valuable features."
"I like that it's stable. It's been stable for a long time, and Microsoft Defender has done a good job there."
"Microsoft 365 Defender is a stable solution."
"Based on what I've seen with Microsoft Defender XDR and the large amount of threat data Microsoft has access to, I'm confident I would trust Microsoft Security to handle the majority of all our threats from any threat actor who's essentially putting our company at risk."
"ReliaQuest GreyMatter has helped us to reduce security incidents by 89%, which is a significant amount of incidents we have seen."
"ReliaQuest GreyMatter saves around 60% of time or resources."
 

Cons

"It would be good if they could make an exception for applications. Sometimes, it can be a bit of a challenge to make exceptions for certain applications that have been used as rogue."
"For working with the solution, you only really need a web browser, however, we've found that working on Chrome, for example, is horrible."
"I recommend adding a data loss prevention (DLP) solution to Cortex XDR by Palo Alto Networks. The inclusion of this feature would allow the application of DLP policies alongside antivirus policies via a single agent and console, making it more competitive as other OEMs often offer DLP solutions as part of their antivirus products."
"The solution should force customers to integrate with network traffic to see the full benefits of XDR."
"The connection to the internet has not performed as expected."
"The onboarding process could be better."
"Cortex XDR by Palo Alto Networks is a very good product, but financially, it is very expensive, so the company should look into that area."
"Currently, if you use Palo Alto endpoint protection as the only solution it's very complicated to remove pre-existing threats."
"There are a few technical issues with Defender XDR that can be improved. Sometimes, the endpoint devices are not reporting properly to the Defender 365 portal. When you're getting all the information from the Microsoft portal, the devices are sometimes not in sync. We have hundreds of endpoint devices, some needing to be onboarded again."
"Improving scalability, especially for very large tenants, could be beneficial for Microsoft Defender XDR."
"The solution could enhance the threat Intelligence feature by making it more relevant to specific industries. Much of the threat intelligence information isn't directly applicable to our environment. It would be beneficial if the threat intelligence were tailored to the industry, such as healthcare or fintech, where the solution is being used."
"The Defender agent itself is more compatible with Windows 10 and Windows 11. Other than these two lines, there are so many compatibility issues. Security is not only about Microsoft. The core technical aspects of it are quite good, but it would be good if they can better support non-Microsoft solutions in terms of putting the agents directly into VMware and other virtualization solutions. There should be more emphasis on RHEL and other operating systems that we use, other than Windows, in the server category."
"There is definitely scope for improvement in the automation area. Because the solution is a SaaS platform, we don't have the overall ability to automate stuff.... There is no direct way to go ahead because it's a SaaS platform."
"The abundance of sub-dashboards and sub-areas within the main dashboard can be confusing, even if it all technically makes sense."
"It would be helpful if the solution could scan faster when it comes to scanning attachments to emails."
"I do think that maybe having a feature within my organization where there are three different domains within which we have to operate would be helpful, as there is currently no unified view within the domains."
"Areas that have room for improvement include user interface and integration."
 

Pricing and Cost Advice

"Its pricing is kind of in line with its competitors and everybody else out there."
"Traps pays for itself within the first 16 months of a three-year subscription. This is attributed to OPEX savings, as security teams spent less time trying to identify and isolate malware for analysis as a result of a reduction in malware incidents, false positives, and breach avoidance."
"It has a higher cost than other solutions, like CrowdStrike or Microsoft’s EDR tools, but it reduces the cost of our operations because it’s a new generation antivirus tool."
"It is present, but when compared to other competitive products, I would say it is not less expensive; however, when all of the other added values are considered, the price is reasonable."
"If one wishes to work with another team or large number of users at a future point, he must purchase a license for them."
"I don't recall what the cost was, but it wasn't really that expensive."
"The cost of Cortex XDR by Palo Alto Networks is $55 to $90 USD per endpoint per month."
"Our customers have expressed that the price is high."
"We have a lot of problems in Latin America regarding the price of Microsoft 365 Defender, because the relationship between dollars and the money of the different countries, it's is a lot. Many customers that have small businesses say that they would like the solution but it is too expensive. However, large companies do not find the cost an issue."
"I would like to have more security features in the lower licenses because not every customer is able to buy E5 licenses. The bundling isn't always easy for our customers to understand. Compared to other tools, it's a good price."
"Microsoft is not competitive with the pricing of the solution. The competitors are able to offer lower discounts. The price of the solution is higher."
"While Microsoft Defender XDR carries a higher cost, its ease of use compared to Defender may justify the investment."
"It has consistently offered highly appealing academic pricing, with distinct rates for higher education and general educational purposes."
"The most valuable licensing option is expensive, so pricing could be improved. Licensing options for this solution also need to be consolidated, because they frequently change."
"Microsoft Defender XDR is already included in our Office 365 licensing. It is better because we're saving money by using it."
"Purchasing Microsoft Defender XDR as part of a Microsoft 365 bundle can be cost-effective, but acquiring it as a standalone product may be more expensive."
Information not available
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Top Industries

By visitors reading reviews
Construction Company
12%
Financial Services Firm
11%
Manufacturing Company
10%
Comms Service Provider
9%
Computer Software Company
9%
Financial Services Firm
9%
Comms Service Provider
7%
Manufacturing Company
7%
Financial Services Firm
11%
Manufacturing Company
9%
Construction Company
7%
Retailer
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise20
Large Enterprise52
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
What needs improvement with ReliaQuest GreyMatter?
Areas that have room for improvement include user interface and integration.
What is your primary use case for ReliaQuest GreyMatter?
I use ReliaQuest GreyMatter for detection and response, XDR, and SIEM. The best features I like about GreyMatter the ...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Information Not Available
Find out what your peers are saying about Microsoft Defender XDR vs. ReliaQuest GreyMatter and other solutions. Updated: April 2026.
900,747 professionals have used our research since 2012.