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Microsoft Defender XDR vs ReliaQuest GreyMatter comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cortex XDR by Palo Alto Net...
Sponsored
Ranking in Extended Detection and Response (XDR)
4th
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
118
Ranking in other categories
Endpoint Protection Platform (EPP) (4th), Endpoint Detection and Response (EDR) (5th), Ransomware Protection (2nd), AI-Powered Cybersecurity Platforms (1st)
Microsoft Defender XDR
Ranking in Extended Detection and Response (XDR)
5th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
108
Ranking in other categories
Endpoint Detection and Response (EDR) (9th), Microsoft Security Suite (4th)
ReliaQuest GreyMatter
Ranking in Extended Detection and Response (XDR)
30th
Average Rating
9.6
Reviews Sentiment
8.1
Number of Reviews
2
Ranking in other categories
Digital Risk Protection (11th), Managed Detection and Response (MDR) (16th)
 

Mindshare comparison

As of September 2026, in the Extended Detection and Response (XDR) category, the mindshare of Cortex XDR by Palo Alto Networks is 4.8%, down from 6.1% compared to the previous year. The mindshare of Microsoft Defender XDR is 3.7%, down from 6.1% compared to the previous year. The mindshare of ReliaQuest GreyMatter is 0.9%, up from 0.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Extended Detection and Response (XDR) Mindshare Distribution
ProductMindshare (%)
Cortex XDR by Palo Alto Networks4.8%
Microsoft Defender XDR3.7%
ReliaQuest GreyMatter0.9%
Other90.6%
Extended Detection and Response (XDR)
 

Featured Reviews

ABHISHEK_SINGH - PeerSpot reviewer
Senior Process Expert at A.P. Moller - Maersk
Gained full visibility and streamlined threat detection through behavior-based insights and AI integration
Initially, we got to have a lot of false positives when we onboarded, but nowadays it's quite smooth. We have fine-tuned our security policies and allowed different levels of policies to get rid of those false positives. Currently, we are getting a fairly good amount of incidents that are not false positives or benign, but actionable items. The process is streamlined. In the initial days, the operations used to get involved in a lot of benign and other activities, but now the process is streamlined. We are leveraging the auto-detection and remediation plans. The operations teams are now more involved in other business roles as well, not just looking into the logs and fetching out what's happening there. They have fixed a lot of things. Initially, they didn't have IAC code drift detection, cloud posture management, or security posture management, but they have those now. They purchased different vendors and did a merger with that. They have now Prisma Cloud that gets integrated and now they are working with Cortex Cloud. Everything that was negative has now been addressed, and the product altogether looks to be in a very better and mature shape now. Currently, it's more or less detecting the workloads with AI-based best practices. Since most organizations are consuming AI agents and other things, we are looking forward to seeing what other feature enhancements Palo Alto can support in that.
reviewer2812758 - PeerSpot reviewer
Infosec at a government with 10,001+ employees
Integrated defenses have unified threat hunting, phishing simulations, and identity investigations
I appreciate Microsoft Defender XDR's MDE, Microsoft Defender tool, which has Attack Simulator. Instead of doing a phishing campaign and getting a separate tool, Microsoft Defender XDR does it all. These features of Microsoft Defender XDR have helped us conduct a phishing campaign quarterly, which has been beneficial. I also appreciate the fact that it has Defender for Office integrated, Defender for Identity, and everything integrated together. I would describe the process of using Microsoft Defender XDR to prioritize incidents in my security operations as quite decent. I appreciate the automatic alerting system where any incidents or alerts we receive come directly to our email. From there, we can open the email, go directly to Microsoft Defender XDR, and start our investigations and remediations. I perceive the integration of security and identity access management in Microsoft Defender XDR as affecting my identity protection strategies very well because it is well integrated with Purview, integrated well with Entra ID, and integrated well with Exchange. I especially appreciate MDO, the Office product. If anything happens and I want to conduct an investigation, it takes me directly to Exchange, where I can also investigate any emails or phishing incidents. Instead of going to different portals, everything can be done from Microsoft Defender XDR. If necessary for further investigation, Microsoft Defender XDR then directs me to that environment. I would assess the integration of AI in guiding security actions within Microsoft Defender XDR as quite positive. Recently, Security Copilot went big, and it is beneficial that I can use that, especially to write KQL. I can do threat hunting features and intelligence all within using Microsoft's Security Copilot. It also has a nice AI feature for threat hunting. I know that all the Defender logs go to Sentinel, and I can pull it up from Microsoft Defender XDR or from Sentinel. The fact that I can actually do all that within Microsoft Defender XDR is a nice feature. In the top module, I can do threat lookups, and I can actually type KQLs in Microsoft Defender XDR and look up incidents. Predictive shielding has had a nice impact on my proactive security measures. It is beneficial that it has, similar to Entra ID, a secure score. For me to improve the product, the secure score helps me out. If I rate it from highest to lowest, I can see what things I can improve. Secure score helps me see what areas I can improve in Microsoft Defender XDR to increase my score and bring it to 80 or more. Knowing Microsoft Defender XDR from using it since 2019, before COVID days, I know that they have improved significantly. It is much more user-friendly and has a very nice vulnerability feature that I find handy and useful. The fact that this feature integrates into Intune is also very decent.
MK
Senior Security Analyst at Tata Consultancy
Unified security monitoring has reduced alert fatigue and improves proactive threat hunting
I use real-time monitoring in ReliaQuest GreyMatter, which significantly improves my security posture. The unified interface helps reduce alert fatigue. I would estimate it saves around 20% in alert fatigue reduction. The automated threat hunting capabilities in ReliaQuest GreyMatter help me stay ahead of threats. The machine learning algorithm benefits my threat intelligence by providing deeper insights and predictions. I use various metrics to rate the success of the predictive threat intelligence in ReliaQuest GreyMatter.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution helps find bugs, and it is safe to use to prevent attacks by hackers."
"It detected stuff that other things wouldn't detect."
"The tool is designed to scale for large enterprises and handle large volumes of data."
"Since they've done their most recent update, the ease to isolate endpoints is valuable. If we find one where there is a virus on it, we can easily isolate it. We don't even have to contact the user. We don't have to manually take them off the network. We can easily isolate them."
"I can highlight that we have not faced any security incidents with Cortex XDR by Palo Alto Networks, and even though our environment is quite dynamic, we have not faced any security incident with Cortex XDR by Palo Alto Networks until now."
"The anti-exploit is impenetrable."
"Cortex XDR by Palo Alto Networks has helped lighten the load of our security analysts because it was the major tool that we were using and the one we utilized most."
"The initial setup is easy."
"Microsoft Defender XDR is scalable."
"Based on my experience, I rate Microsoft Defender XDR as nine out of ten."
"The portal is quite user-friendly. There is integration with Office, Intune, and other products from the same portal. From there, we can see which policies are installed on a particular machine. We also can manage devices, groups, and tagging."
"The integration between all the Defender products is the most valuable feature."
"We are able to consolidate licences and make use of many Microsoft products using this solution, and if we have any Microsoft customers, we encourage them to use this solution for enterprise defence."
"Vulnerability assessment and just-in-time access are some valuable features of Defender for server plans."
"The Email Explorer feature has proven invaluable, offering a broader perspective than automated alerts and incidents alone."
"365 Defender saves us a lot of money because we don't have to recover data or hire outside lawyers to help us with legal trouble."
"ReliaQuest GreyMatter saves around 60% of time or resources."
"ReliaQuest GreyMatter has helped us to reduce security incidents by 89%, which is a significant amount of incidents we have seen."
 

Cons

"This is a very costly product."
"Cortex XDR by Palo Alto Networks is a strong tool, but it is true that digesting information sometimes makes the tool go a little bit slower."
"For Cortex XDR by Palo Alto Networks, if I had to point out improvements, I would say the UI is still somewhat difficult for beginners."
"Being able to filter the events to see those that are related to the actual alert would save time spent by the engineer."
"The server sometimes stops continuously to check things so it would be helpful to receive access updates or technical reasons."
"I have seen lagging with Cortex XDR by Palo Alto Networks. There was one time when we faced a threat actor trying to gain access to our system. When our team utilized the tool, we were all on the same dashboard and we faced a lag issue at that time of around five minutes, which was quite significant."
"The solution should force customers to integrate with network traffic to see the full benefits of XDR."
"It's not an ideal choice for smaller businesses, as you need a minimum of 200 endpoints to even use the solution at all."
"The cost can be high if you want to build custom license packages. Another area for improvement is the policies. In Azure, we need to implement policies in JSON format, but in 365 Defender 365, it would be helpful to use a different format so we can customize the platform."
"The price could be better. It'll also help if they can continuously update and upgrade the solution. Every day there's a new virus uploaded into the network, and we have to keep updating it to identify all these things."
"There are a few technical issues with Defender XDR that can be improved. Sometimes, the endpoint devices are not reporting properly to the Defender 365 portal. When you're getting all the information from the Microsoft portal, the devices are sometimes not in sync. We have hundreds of endpoint devices, some needing to be onboarded again."
"When we do investigations, it would be better if Microsoft could populate the host dashboard more. When we open any host for investigation, we want the entire timeline of what is happening on the host, including all the users logging in, their hardware, Windows version, etc."
"The support could be more knowledgable to improve their offering."
"Every now and then, Microsoft Defender XDR seems to go through and aggregates almost a week's worth of incidents and wraps them up, indicating a huge problem."
"Defender also lacks automated detection and response. You need to resolve issues manually. You can manage multiple Microsoft security products from a single portal, and all your security recommendations are in one place. It's easy to understand and manage. However, I wouldn't say Defender is a single pane of glass. You still need to switch between all of the available Microsoft tools. You can see all the alerts in one panel, but you can't automate remediation."
"Microsoft Defender XDR could be improved in terms of speed, especially backend speed."
"Areas that have room for improvement include user interface and integration."
 

Pricing and Cost Advice

"The price was fine."
"Cortex XDR by Palo Alto Networks is an expensive solution."
"In terms of the cost Cortex XDR by Palo Alto Networks is very expensive because we are a Mexican company and when you translate dollars to pesos the cost is very high. The solution is very expensive for Mexican companies. I understand that they have international prices, but I do not think it offsets the price enough for many companies in countries, such as Mexico. The amount it is reduced is not a massive percentage."
"I don't like that they have different types of licenses."
"It's about $55 per license on a yearly basis."
"It has a higher cost than other solutions, like CrowdStrike or Microsoft’s EDR tools, but it reduces the cost of our operations because it’s a new generation antivirus tool."
"I am using the Community edition."
"Cortex XDR’s pricing is very reasonable."
"Understanding the subscription model has been a bit challenging, as every feature or requirement comes with an additional cost."
"Its licensing and pricing are handled by someone else. My role is limited to incidents or issues with the portal, but you get what you pay for. It is worth the cost."
"I find the pricing to be quite competitive, especially considering its inclusion in our E5 subscription, which provides a comprehensive set of functionalities."
"They have moved from a licensing model to pay-per-use... The question is: What happens if, for any reason, there's not enough budget to accept this model? That could be a great problem."
"Purchasing Microsoft Defender XDR as part of a Microsoft 365 bundle can be cost-effective, but acquiring it as a standalone product may be more expensive."
"Microsoft Defender XDR's licensing is complicated."
"On average, we pay around 55 euros per user for the services and features we receive."
"The solution is affordable, and we haven't been hit with any hidden costs. The subscription model is straightforward, and it's easy to understand how much additional features cost. If we need to cancel a license or feature, we do that well in advance to avoid being charged for it, but overall, the pricing and licensing are simple and easy."
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Top Industries

By visitors reading reviews
Outsourcing Company
12%
Comms Service Provider
12%
Construction Company
11%
Financial Services Firm
9%
Financial Services Firm
9%
Computer Software Company
8%
Outsourcing Company
8%
Comms Service Provider
8%
Financial Services Firm
10%
Manufacturing Company
9%
Construction Company
8%
Retailer
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise21
Large Enterprise55
By reviewers
Company SizeCount
Small Business46
Midsize Enterprise28
Large Enterprise41
No data available
 

Questions from the Community

Cortex XDR by Palo Alto vs. Sentinel One
Cortex XDR by Palo Alto vs. SentinelOne SentinelOne offers very detailed specifics with regard to risks or attacks. ...
Comparing CrowdStrike Falcon to Cortex XDR (Palo Alto)
Cortex XDR by Palo Alto vs. CrowdStrike Falcon Both Cortex XDR and Crowd Strike Falcon offer cloud-based solutions th...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface,...
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with the pricing, setup costs, and licensing of Microsoft Defender XDR is that we are on an E5 license,...
What needs improvement with Microsoft 365 Defender?
From my perspective, Microsoft Defender XDR can be improved with better visibility in certain areas where I can trigg...
What is your primary use case for Microsoft 365 Defender?
My main use cases for Microsoft Defender XDR are telemetry, advanced hunting, and the ability to perform host isolati...
What needs improvement with ReliaQuest GreyMatter?
Areas that have room for improvement include user interface and integration.
What is your primary use case for ReliaQuest GreyMatter?
I use ReliaQuest GreyMatter for detection and response, XDR, and SIEM. The best features I like about GreyMatter the ...
 

Also Known As

Cyvera, Cortex XDR, Palo Alto Networks Traps
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
No data available
 

Overview

 

Sample Customers

CBI Health Group, University Honda, VakifBank
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Information Not Available
Find out what your peers are saying about Microsoft Defender XDR vs. ReliaQuest GreyMatter and other solutions. Updated: August 2026.
913,924 professionals have used our research since 2012.