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ThreatLocker Zero Trust Platform vs Trellix Advanced Threat Defense comparison

Why PeerSpot?
 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 17, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

ThreatLocker Zero Trust Pla...
Ranking in Advanced Threat Protection (ATP)
5th
Average Rating
9.2
Reviews Sentiment
7.1
Number of Reviews
83
Ranking in other categories
Network Access Control (NAC) (3rd), Endpoint Protection Platform (EPP) (5th), Application Control (1st), ZTNA as a Service (5th), ZTNA (6th), Ransomware Protection (1st)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of September 2026, in the Advanced Threat Protection (ATP) category, the mindshare of ThreatLocker Zero Trust Platform is 2.7%, up from 2.3% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
ThreatLocker Zero Trust Platform2.7%
Trellix Advanced Threat Defense2.1%
Other95.2%
Advanced Threat Protection (ATP)
 

Featured Reviews

Santo Joy - PeerSpot reviewer
Head Of Cyber Security at a outsourcing company with 201-500 employees
Security controls have been strengthened with granular application, ringfencing, and access policies
The features of ThreatLocker Zero Trust Endpoint Protection Platform that I like the most are the Ringfencing, elevation control, storage control, and application whitelisting functionality. For examples of how these features benefit my company, we were looking for a solution across various vendors to actually implement application whitelisting controls. ThreatLocker's agent, which is very lightweight and does not use much CPU or RAM, helped us achieve that solution. Ringfencing was an add-on that ticked off a lot of Australian framework security controls, which is the reason we chose it. My impression of the allowlisting feature in terms of managing which software, scripts, and libraries run on my devices is that ThreatLocker's community page has a lot of information around this, which is very helpful. Not only that, the Cyber Hero support that ThreatLocker provides gives us insights and best practices, helping us achieve that solution and guiding us to the right platform. The impact of Ringfencing on controlling the behavior of approved applications has been a big winner for us because it is something that many other platforms do not provide as a functionality. Having that allowed us to identify what applications talk to each other, which is something that many other platforms do not do. The network control feature impacts my ability to manage network traffic across my endpoints and servers. We have not used this widely across all our partners, but wherever required, we use it. It has been an easy solution for those customers to get that control implemented. The elevation feature's role in facilitating just-in-time administrative access for approved applications shows that elevation control helps in many use cases involving remote control platforms, door usage, and security system platforms that require local admins. There are many solutions that provide this functionality, but the licensing cost seems to be expensive, and it also adds another solution into the mix. Rather than doing that, we try to use ThreatLocker Zero Trust Endpoint Protection Platform to achieve that control. Regarding the storage control feature, I have used it. The primary function is USB blocking, which is very widely adopted, and also just locking down and allowing certain users to access certain file locations helps us there. When it comes to enforcing policy-driven access over various storage devices, it depends on the business risk adapted by the companies that we support, but generally the use case is USB and external storage devices where companies know that is a risk, but they do not have appropriate solutions. There are EDR platforms that claim to do this, but ThreatLocker Zero Trust Endpoint Protection Platform does it at an advanced level. My assessment of the efficiency of the real-time threat intelligence and category controls employed by Web Control in blocking malicious and non-compliant sites leads me to think that Web Control is another functionality within ThreatLocker Zero Trust Endpoint Protection Platform that is an add-on on top of the current set. That is another solution that we use based on what is required for the company, but again, that is not widely adapted yet for our partners.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The customer service is excellent, ten out of ten."
"The Zero Trust factor is valuable because it blocks everything. That helps us to stay ahead of bad actors. We do not have to be in recovery mode."
"If all of our vendors would act and support us like ThreatLocker does, we would be happy."
"ThreatLocker Zero Trust Endpoint Protection Platform benefits our company because we can be secure while remaining relaxed, as we are only expecting normal behavior and nothing unusual."
"The interface is clean and well-organized, making it simple to navigate and find what we need."
"I would rate it a ten out of ten."
"The great thing is that if you get a malicious email and you try to run something, ThreatLocker is not going to let it do anything. It is not going to let anything infect your network."
"The unified alerts are useful."
"It was easy to set up initially."
"Provides good exfiltration, and is an all-in-one product."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"This solution is very easy to use and requires little to no training."
"The most valuable features are the administration console and its detection and response module."
"It is very scalable."
"I recommend this solution because of its ease of use."
"The product is expensive, but it is better than the rest of them in the industry."
 

Cons

"I took off one point because sometimes it can be a bit complicated for new engineers, such as my teammates, especially for those who don't have hands-on experience."
"It would be beneficial to have a tighter integration into PSA systems so that approvals can be done directly without having to leave the PSA."
"From one to ten, I would rate the solution overall as a nine out of ten just because the initial setup was a little confusing."
"ThreatLocker Zero Trust Endpoint Protection Platform can be improved by exploring ways of ensuring it is deployed deeper in the device rather than through an extension on the browser and finding ways to integrate all browsers."
"It would be beneficial if it became more recognized in the EU to gain respect."
"Identifying areas of improvement is challenging, however, perhaps adding a few more built-ins could help."
"It has not reduced helpdesk tickets. It has probably increased them by blocking applications and doing its job, resulting in people raising more tickets to know why they cannot use certain things."
"ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"We'd like them to be better at dealing with script threats."
"Lacks remote capabilities not dependent on the internet."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"Make the ATD appliance a part of the whole product offering and take the whole thing onto the cloud."
 

Pricing and Cost Advice

"I can't complain. Cheaper would always be nice, but I think it's reasonable compared to other software in the cybersecurity market."
"The price is very reasonable, and we have been able to integrate ThreatLocker with all of our clients."
"The pricing is pretty fair, considering other solutions. Licensing-wise, it did not take long."
"The pricing is reasonable and normal. I do not have any problems with the cost."
"The pricing works fine for me. It's very reasonably priced."
"I find ThreatLocker's pricing to be reasonable for the services it provides."
"Considering what this product does, ThreatLocker is very well-priced, if not too nicely priced for the customer."
"I believe ThreatLocker's pricing model is fair and flexible, allowing account managers to offer customized deals based on our specific needs."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Manufacturing Company
11%
Financial Services Firm
11%
Computer Software Company
11%
Outsourcing Company
9%
Construction Company
16%
Outsourcing Company
14%
Comms Service Provider
11%
Financial Services Firm
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business59
Midsize Enterprise14
Large Enterprise13
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
I am not sure about operational or cost expenses because we have not really experienced that.
What needs improvement with ThreatLocker Allowlisting?
When it comes to ThreatLocker Zero Trust Platform's policy making, it is very granular, but the moment you zoom out, you have a lot of information or a lot of alerts. However, the moment you zoom i...
What is your primary use case for ThreatLocker Allowlisting?
ThreatLocker Zero Trust Platform's main use case for us was data storage access control.We used ThreatLocker Zero Trust Platform for identifying the most critical and sensitive information of the o...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

Protect, Allowlisting, Network Control, Ringfencing
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Information Not Available
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about ThreatLocker Zero Trust Platform vs. Trellix Advanced Threat Defense and other solutions. Updated: September 2026.
913,806 professionals have used our research since 2012.