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Cisco Secure Email Threat Defense vs Fortra's Agari comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
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Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
25th
Average Rating
8.0
Reviews Sentiment
7.1
Number of Reviews
14
Ranking in other categories
No ranking in other categories
Fortra's Agari
Ranking in Email Security
38th
Average Rating
8.6
Reviews Sentiment
7.2
Number of Reviews
4
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of July 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.3%, down from 16.9% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Fortra's Agari is 0.7%, up from 0.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
TF
Helps to detect and generate reports on phishing emails and saves from email compromises
We use the solution for marketing and brand protection.  I am impressed with the tool's discovery capabilities which help me find out who is sending the emails on the company's behalf. I also find the ability to detect and generate reports on phishing emails a valuable feature.  The product's…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The product's scalability is good."
"The DLP feature of Microsoft Defender for Office 365 is valuable, and we also use the DLP feature for email real-time detection."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"Does a thorough job of examining email and URLs for malicious content."
"Microsoft Defender for Office 365 helps people to work remotely. It is a secure solution. We don't need to use our company's computers or get VPN connections to the networks. I can control how they share screens and what they send to the devices. It keeps our organizations confidential and sensitive information safe."
"It has significantly decreased my time to detection and response."
"The initial setup was easy."
"The two main features that prove most beneficial for us are URL scanning and attachment scanning."
"The product offers protection, email security, anti-spam, and antivirus."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"It's very easy to deploy and configure."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"The solution is stable."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"If spam or some kind of malicious email gets past Mimecast and gets into our email environment, we can go into Agari and we can search for it."
"It comes with a lot of helpful tips for complicated areas."
"It is really important for large companies to have the brand protection that is provided by Agari."
"I am impressed with the tool's discovery capabilities which help me find out who is sending the emails on the company's behalf. I also find the ability to detect and generate reports on phishing emails a valuable feature."
 

Cons

"The UI needs to be more user-friendly."
"The phishing and spam filters could use some improvement."
"Too many false positives and lacks an accurate capability to detect malicious SharePoint sites."
"Microsoft Defender for Office 365 should improve the troubleshooting tools. It's unclear whether the device is blocked at the firewall level or at the device itself. The granularity needed for troubleshooting is currently lacking. From my perspective, Microsoft should address this issue to benefit many users who likely share the same sentiment."
"There's room for improvement regarding the time frame for retrieving emails."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"We need a separate license and we don't know how to get the license that is required."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The pricing could always be better."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The physical appliance has been discontinued, although the platform still exists."
"The solution is a bit expensive."
"We encounter issues while searching for missing emails."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"Some customers in the financial sector do not like the cloud solution because they don't want data to be transferred to a US-based cloud."
"The protocol is quite complicated, which may not be something that could be improved, but it would be better if it was simplified."
"The product's user interface is clunky. We have difficulty in finding what we need. I would also like to see automation in the onboarding processes."
 

Pricing and Cost Advice

"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"It's a user-base subscription."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"The license is expensive because the cost is based on the number of users."
"The pricing has become expensive."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The price of the licensing is based on the volume of email."
"The tool is not expensive and I would rate its pricing a four out of ten."
"The pricing depends on the number of users; per how many mailboxes you have, but they're pretty negotiable with that, too."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
29%
Healthcare Company
7%
Government
6%
Manufacturing Company
6%
Financial Services Firm
15%
Computer Software Company
13%
Media Company
11%
Manufacturing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty ...
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Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
No data available
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
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Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Fortra's Agari and other solutions. Updated: June 2025.
860,592 professionals have used our research since 2012.