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Cisco Secure Email Threat Defense vs Kiteworks comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Apr 20, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Kiteworks
Ranking in Email Security
31st
Average Rating
8.6
Reviews Sentiment
6.9
Number of Reviews
13
Ranking in other categories
Enterprise Content Management (14th), Managed File Transfer (MFT) (10th), Content Collaboration Platforms (15th), Secure Email Gateway (SEG) (11th)
 

Mindshare comparison

As of May 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.9%, down from 18.3% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, down from 1.2% compared to the previous year. The mindshare of Kiteworks is 0.3%, up from 0.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
Sukkanta Banerjee - PeerSpot reviewer
Two-factor authentication and .ZIP format make large file transfers very secure
The most valuable feature is the ability to send a large file of 30 GB in size and more. In Outlook and other email applications, you cannot send files that are larger than 20 MB. But with Kiteworks, 30 GB is transferable by default and, with the proper approval, a file of up to 100 GB can be sent. It makes file transfer very easy and smooth. Also, only the .ZIP format is supported because it is a very secure mode of file transfer, and that is why it is recommended. It also has built-in antivirus, so if it detects any malware it will quarantine the file and it won't be delivered. This is really important to keep the service up and running in a proper and secure manner. With people working from home, the data needs to be checked to see what kind of data is being sent. It has a two-factor authentication mechanism. For example, if a person with a particular domain is using Kiteworks and sends a file to a party outside of his domain, that external party has to go through two-factor authentication. The receiver gets a link that takes them to the setup of a temporary account, which will be valid for three days. The recipient will also receive a customized password separately. Only after all these steps will they be able to access the file. That access is only available to a person with the mail ID to which the file was sent. In addition, admins can see who is sending sensitive content, what that content is, and to whom it is being sent, and can track emails. One week of good training will give a user complete knowledge for using the solution. The system is very easy to use. You just click on "Compose," attach a file, and send it. It's very easy compared to Outlook or Teams. It's quite simple, even for someone logging in for the first time. It is very smooth and easy to send files.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."
"The good part is that you don't have to configure it, which is very convenient."
"The product's scalability is good."
"Does a thorough job of examining email and URLs for malicious content."
"The ability to respond to threats if very important."
"Scalability-wise, I do not think there are any issues so far."
"The product is not resource-intensive."
"The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"I highly recommend it as one of the best choices."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Secure Email Threat Defense's scalability is good."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"It has an efficient email filtering feature."
"It's very easy to deploy and configure."
"We could see whether the customer with whom we shared a file had downloaded it, which was not available with GitHub."
"The solution removes the limitations with file attachment size that is found with regular email."
"I like Kiteworks or Accellion because it's continuously upgraded. I also know that it probably works with a lot of clients."
"The top two features are the two-factor authentication, which is pretty good. It's easily understood by the users. And their API is rather robust. We have numerous integrations that work off the API."
"The benefits that Kiteworks has provided to its customers in terms of data sovereignty."
"The most valuable feature is the ability to send a large file of 30 GB in size and more. In Outlook and other email applications, you cannot send files that are larger than 20 MB. But with Kiteworks, 30 GB is transferable by default and, with the proper approval, a file of up to 100 GB can be sent. It makes file transfer very easy and smooth."
"The most valuable feature is the ability to allow end-users to manage their own information and data with minimal administration. That's the best feature from my perspective."
"I can identify from which region our users are uploading or downloading files."
 

Cons

"We still see many false positives from time to time with Microsoft Defender for Office 365, so it would be good if we can reduce those false positives and provide better workflows for our end users, as sometimes they may not know what to do when they encounter a false positive."
"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"Configuration requires going to a lot of places rather than just accessing one tab."
"Microsoft Defender for Office 365 should be more proactive."
"The phishing and spam filters could use some improvement."
"The XDR dashboard has room for improvement."
"Microsoft wants its well-paying customers to finish testing some of its half-baked products, find bugs, and report bugs back to Microsoft's team, which is a little frustrating for those who have to manage it and roll it up to thousands of people across the organization."
"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"The pricing could always be better."
"The physical appliance has been discontinued, although the platform still exists."
"The solution is a bit expensive."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"This solution could be improved by integration with Sandbox."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"It could be more stable. In the next release, it would be better if it was more stable with improved performance."
"There is no offboarding process for end-users in Kiteworks. It's a manual process. There is no automated syncing with LDAP and checking to see if the account is still active. It's a manual process to get people out of here, which isn't the best way."
"I noticed the Kiteworks login UI is very basic, lacking customization. Allowing more HTML tags to add hyperlinks or user-friendly information on the home page would be very useful."
"In my experience, their technical support can be a little slow."
"We have experienced a few hiccups and bugs when using the admin console and from a user perspective."
"There are always issues when there are bugs or upgrades. The challenge with upgrading is getting more storage from the customer. Every time we have a new version, it requires additional storage. This means that the customer would need to procure more storage for their server, which they don't like because it means additional cost to them. So, I think my request would be that the version upgrades don't require any significant storage requirement."
"The one feature, which I have also requested directly to Kiteworks, is to have a scheduled upgrade function. Currently, one of my engineers logs in after hours for the upgrade. We're a hospital, and we're 24/7, but the primary users are seven to five. So, we log in the early evening just to push a button to tell it to do the update. It would be nice if that could be very easily scheduled."
"Kiteworks could benefit from enhancing the proposal knowledge base section, specifically regarding the type of work involved. Currently, the knowledge base seems insufficiently dedicated to this topic, making it challenging for new users to access the relevant administrative law. Improving the visual aids and providing clearer explanations could alleviate this issue."
 

Pricing and Cost Advice

"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"I know that the product is incredibly expensive."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"The license is expensive because the cost is based on the number of users."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"The product is very expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"The solution is very expensive because we are buying with Malaysian Ringgit and it's sold in US dollars."
"The license management is changing and confusing. If I could make one change to it, it would be better license management through the API."
"The price of Kiteworks is reasonable."
"It is not really expensive. I mean, to me it's obviously expensive, but it's worth it."
"I believe it's a little costly, but given the faith that we put into it from a security perspective to maintain the integrity of our patient information that is being transferred through this system, that's a small price to pay. So, on the surface, it might look like a lot of money, but depending on the need for security, which is where we feel it shines, it's okay price-wise."
"They changed it midstream. We were being charged a certain flat rate for SFTP traffic. For whatever reason, at the beginning of the year, our pricing changed, and we are now being charged more for using a feature of the product than we were when we first bought it. That has been our experience with billing. It turned out to be more expensive than when we started with it."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
34%
Financial Services Firm
6%
Government
5%
Healthcare Company
5%
Government
14%
Financial Services Firm
13%
Computer Software Company
8%
Manufacturing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What is Kiteworks?
Kiteworks is a secured file sharing platform that enables users to collaborate with different parties across a robust...
What do you like most about Kiteworks?
The benefits that Kiteworks has provided to its customers in terms of data sovereignty.
What needs improvement with Kiteworks?
I'm not a network expert, however, there must be some room for improvement. Perhaps there could be a notification to ...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Accellion
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
United States Securities and Exchange Commission, National Health Service, Husch Blackwell LLP, NYC Health + Hospitals, Viatris, MITRE Corporation, Chubb, Kraft Heinz, KPMG, Kohler, National Institute of Standards and Technology, Purdue Pharma, AVL
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Kiteworks and other solutions. Updated: April 2025.
851,604 professionals have used our research since 2012.