No more typing reviews! Try our Samantha, our new voice AI agent.

Cisco Secure Email Threat Defense vs Proofpoint Email Protection comparison

Why PeerSpot?
 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
22nd
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Proofpoint Email Protection
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
110
Ranking in other categories
Advanced Threat Protection (ATP) (5th), Digital Risk Protection (5th), Office 365 Protection (1st), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of November 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Proofpoint Email Protection is 5.9%, down from 7.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Proofpoint Email Protection5.9%
Cisco Secure Email Threat Defense1.1%
Other93.0%
Email Security
 

Featured Reviews

GC
Senior Cybersecurity Engineer at a financial services firm with 11-50 employees
Provides robust email security features but requires improved modernization and complexity management
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilities. The initial setup is not straightforward and requires expertise and time to master configurations such as spoofing and DLP. More control over backend functionalities and simplifying rule management could enhance user experience. The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration. Furthermore, the pricing might deter new users who could opt for alternative, more cost-effective solutions.
Siva_Prasad - PeerSpot reviewer
Senior Consultant at a tech vendor with 10,001+ employees
Email defenses have reduced phishing incidents and protect sensitive data across our enterprise
As things are evolving and threats develop in unpredictable ways, Proofpoint must adopt AI solutions and agentic solutions more aggressively and provide them to customers as part of service offerings. Inbuilt AI solutions would add more value and make Proofpoint a more premium choice for customers. With the help of AI solutions, agentic AI, and generative AI capabilities, the product would be more efficient than it currently is. Filtering false positives is highly challenging because it is impossible for humans to identify which emails are genuine and which are spam. Proofpoint should focus more on this area with back-end agents or other tools. Proofpoint should decide which emails are genuine and which are spam so it is not a challenge for end users. When receiving an email, end users should not have to determine whether to respond or not. Proofpoint should not release such spam emails and should strictly block such spam and spoof emails based on connection IPs. Currently, false positives occur in the product, and while this occurs in every product, it is an area where Proofpoint can focus on improving and reducing false positives. One email is enough for an end user to be deceived and lose money, so addressing this area is critical.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It's very easy to deploy and configure."
"This solution is easy to use."
"Currently, the ease of deployment is the low-hanging fruit for Cisco email security."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Cisco Secure Email Threat Defense's best features include user management of graymail, enhancing security awareness by allowing users to manage cold calls, sales-based items, and ensuring email compliance."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The features and functionalities are much better than Microsoft's in-built Defender plan, and this product has helped us to protect our organization from any malware attack in the past."
"Proofpoint Email Protection positively impacts my organization because it is a simpler solution in terms of user interaction compared to my previous email gateway, and its detection capabilities are considerably more advanced."
"Proofpoint Email Protection has positively impacted my organization by simplifying the analysis of emails since it provides segregated statements that highlight the important parameters we need to check, allowing us to efficiently conclude if the alerts are false positives or true positives."
"Proofpoint Email Protection ensures users have clean mailboxes and are not bothered by unwanted email."
"In terms of detection of spam, malware, and virus, the detection is 99.9% accurate."
"The initial implementation is pretty easy to handle."
"From a business perspective, the solution was very helpful as it speeded our business flow and increased email delivery."
"Proofpoint Email Protection has positively impacted our organization in a very fruitful way."
"URL scanning and online relay service are the most valuable features of Proofpoint Email Protection."
 

Cons

"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The solution is a bit expensive. It could be cheaper."
"This solution could be improved by integration with Sandbox."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The search area has room for improvement."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"Proofpoint Email Protection provides a solution for user training, which I did not end up going with because I chose KnowBe4. That is the only part I did not appreciate about it."
"To move to a more sophisticated email security solution was cost-prohibitive. When you compare it to others, it was too expensive."
"While ingesting the logs into our SIEM tool, most organizations don't have the capability to buy the email gateway as it is quite an expensive one."
"It became very expensive due to the nature of local circumstances, and I may advise Proofpoint to adjust marketing solutions based on each country."
"Regarding improvements or enhancements in Proofpoint Email Protection, I find the platform somewhat chaotic. It has too many different sections that perform the same function, which is very confusing."
"We find the cost to be prohibitive."
"The product's deployment is complex and requires technical knowledge."
"The largest complaint that we hear from our customers is that there is no local support."
 

Pricing and Cost Advice

"The solution’s pricing is manageable."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"In general, the pricing is competitive."
"It is expensive."
"Proofpoint Email Protection has comparable pricing."
"The end customer is buying our solution, which can be for monthly or annual usage depending on our payment and business model."
"The licensing is basically $8/user."
"The solution charges per user per month to use it. There are not any additional fees in addition to the standard living fees."
"The solution is expensive."
"The solution uses a licensing model that is reasonable compared to other products."
report
Use our free recommendation engine to learn which Email Security solutions are best for your needs.
920,939 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Marketing Services Firm
11%
Outsourcing Company
9%
Comms Service Provider
9%
Healthcare Company
9%
Financial Services Firm
13%
Outsourcing Company
10%
Manufacturing Company
10%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business31
Midsize Enterprise23
Large Enterprise62
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What needs improvement with Proofpoint Email Protection?
To improve Proofpoint Email Protection, I suggest breaking down the URL into one versus three different GUIs. Regarding Proofpoint Email Protection's AI capabilities, I think its governance and sec...
What is your primary use case for Proofpoint Email Protection?
My main use case for Proofpoint Email Protection includes phishing emails, spam, URL isolation, and training. I utilize the email protect portal to ensure that none of our employees in any of the b...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Proofpoint Enterprise Protection, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Proofpoint Email Protection and other solutions. Updated: November 2026.
920,939 professionals have used our research since 2012.