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Cisco Secure Email Threat Defense vs Proofpoint Email Protection comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Proofpoint Email Protection
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
55
Ranking in other categories
Advanced Threat Protection (ATP) (4th), Digital Risk Protection (3rd), Office 365 Protection (2nd), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of January 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Proofpoint Email Protection is 7.9%, down from 8.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Proofpoint Email Protection7.9%
Cisco Secure Email Threat Defense1.1%
Other91.0%
Email Security
 

Featured Reviews

reviewer2541525 - PeerSpot reviewer
Principal Cyber Prevent and Defense Engineer at a comms service provider with 1,001-5,000 employees
Clawback feature performs well but analytics and integration capabilities need improvement
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty in sending logs to our SIEM. Cisco Secure Email Threat Defense's flexibility could be enhanced while it mostly integrates with cloud solutions, but not on-premise. The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious. Regarding room for improvement, the significant number of false positives should be addressed. The solution does not adapt to behavioral analytics and does not make changes when it sees a pattern.
Steve Bradbury - PeerSpot reviewer
Consultant at Exelixis Inc
Email defenses have blocked advanced threats and provide deep visibility into risky users
The areas that have room for improvement in Proofpoint Email Protection include their cost of ownership, which is fairly high. To manage and run all their products, I have to list and manage administrators in seven or eight different places. That is too many places to keep track of since for this tool I have to go to one location, and for another tool I have to go to a different location. They need to simplify the administration management of administrators and consolidate that into one place for all their products. Access to all the different products is very scattered. For some products I go to one URL, and for different products I go to a different URL. They have a threat URL that has most of their products in it, but not all. They need to simplify the interface to show all the products I have access to in one location.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Cisco Secure Email Threat Defense's best features include user management of graymail, enhancing security awareness by allowing users to manage cold calls, sales-based items, and ensuring email compliance."
"Secure Email Threat Defense's scalability is good."
"The solution is stable."
"It's very easy to deploy and configure."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Proofpoint Email Protection is the best solution from the perspective of email security."
"The most valuable feature is the option to edit the inbound security."
"A one-stop shop for email protection"
"The anti-spam features are excellent on the email firewalls."
"The solution's technical support is good. I rate the technical support a ten out of ten."
"Its anti-phishing functionality is the most valuable. Certainly, the biggest problem I have is phishing."
"The setup was easy."
"The solution scales quite well."
 

Cons

"This solution could be improved by integration with Sandbox."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"We encounter issues while searching for missing emails."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"It has too many screens. It is kind of a conglomeration of products. In other words, they built product A, product B, and product C, and they are yet to integrate them into a single administrative console. I would certainly like to see a more seamless administrative interface. I would also like to see them include more bang for the buck, by including features like email fraud protection, rather than making their product so piecemeal, where you are buying little pieces. I agree with the idea of having multiple tiers or layers, but maybe as small, medium, and large, as opposed to an a la carte menu."
"Integration for reporting needs to be improved, it's too complex."
"The setup requires expertise. It needs someone with experience on managing it, and I would rate the implementation as needing someone experienced."
"Proofpoint Email Protection could improve the Mail Trace feature and make navigation easier."
"The stability and UI are the two areas of the solution with certain shortcomings that need improvement."
"The scalability can be improved, and the solution can be optimized."
"We find the cost to be prohibitive."
"Sometimes it doesn't detect actual spam emails, and sometimes it catches normal emails."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"I rate the price of Proofpoint Email Protection a four out of five."
"Proofpoint Email Protection has comparable pricing."
"The solution is expensive."
"It is multiple times more expensive, which made it very much less attractive."
"Pricing has recently been increased and the cost is a downside"
"Proofpoint Email Protection is a reasonably priced product, which means that it is neither too low nor too high in terms of price."
"The solution charges per user per month to use it. There are not any additional fees in addition to the standard living fees."
"They are competitively priced, but I have been forced to get quotes for other solutions now because they haven't been responding to requests to do the work that we would like them to do."
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Marketing Services Firm
8%
Manufacturing Company
8%
Healthcare Company
7%
Financial Services Firm
11%
Computer Software Company
10%
Manufacturing Company
8%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise14
Large Enterprise18
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What is your experience regarding pricing and costs for Proofpoint Email Protection?
In terms of pricing, it is okay compared to others. I would say it is normal. Additional costs do come in, but it enhances security.
What needs improvement with Proofpoint Email Protection?
I believe they still need to improve by consolidating some portals, as currently, you have to log in separately to a few of them.
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Proofpoint Enterprise Protection, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Proofpoint Email Protection and other solutions. Updated: December 2025.
881,082 professionals have used our research since 2012.