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Cisco Secure Email Threat Defense vs Proofpoint Email Protection comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
27th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Proofpoint Email Protection
Ranking in Email Security
3rd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
53
Ranking in other categories
Security Awareness Training (2nd), Digital Risk Protection (3rd), Office 365 Protection (2nd), Secure Email Gateway (SEG) (3rd)
 

Mindshare comparison

As of October 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 0.9% compared to the previous year. The mindshare of Proofpoint Email Protection is 8.2%, down from 9.0% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Proofpoint Email Protection8.2%
Cisco Secure Email Threat Defense1.1%
Other90.7%
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
AhmedRamadan - PeerSpot reviewer
Optimize email security with effective sandboxing and auto Pull for quarantine
Proofpoint is used as an email security gateway for big enterprises, primarily for their on-premises servers. Many customers also use it alongside Office 365 Proofpoint offers a complete solution for email security with features like DLP, email archiving, and encryption. The most valuable…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"It's very easy to deploy and configure."
"Secure Email Threat Defense's scalability is good."
"It has an efficient email filtering feature."
"This solution is easy to use."
"I highly recommend it as one of the best choices."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"The most valuable features of Proofpoint Email Protection are the performance from being on the cloud."
"Proofpoint is the main tool for blocking spam because it denies the connection altogether."
"The spam filter for email is good."
"The solution blocks malicious emails containing viruses and malware and reduces them out of spam."
"Compared to other products, Proofpoint's real-time threat intelligence makes it less noisy; they collect and share threat information effectively, which benefits all customers."
"The solution scales quite well."
"The Tap and Trap features. They are the best features."
"I like all the features with Proofpoint, such as how it filters the spam and marketing mail, lost reality mail, blocks phishing attacks, blocks malicious attachments, and stops phishing links. Also it can defend against the business email compromise impersonation technique. It is a complete solution for all email attacks. It filters for the bad, malicious attachments. If there is any executable file, it can be deleted. It is a good, complete solution."
 

Cons

"The pricing could always be better."
"We encounter issues while searching for missing emails."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The solution is a bit expensive."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"This solution could be improved by integration with Sandbox."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"Proofpoint Email Protection could improve the Mail Trace feature and make navigation easier."
"The support team was a bit slow."
"The setup requires expertise. It needs someone with experience on managing it, and I would rate the implementation as needing someone experienced."
"We'd like to have the ability to create more customized reports."
"I believe they still need to improve by consolidating some portals, as currently, you have to log in separately to a few of them."
"I would want better spear phishing protection in the essentials package."
"The solution could be improved with the addition of PLP and email encryption features."
"Proofpoint should have better integration with complex environments that need more than one instance of Proofpoint, as there are issues with nested instances."
 

Pricing and Cost Advice

"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"I rate the price of Proofpoint Email Protection a four out of five."
"It is expensive."
"Annually, it costs us about $92,000. This is pretty much what it costs us. There is no additional cost."
"They are competitively priced, but I have been forced to get quotes for other solutions now because they haven't been responding to requests to do the work that we would like them to do."
"I rate the product price a seven on a scale of one to ten, where one is low price and ten is high price."
"The licensing is basically $8/user."
"The price is reasonable."
"It is multiple times more expensive, which made it very much less attractive."
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Top Industries

By visitors reading reviews
Computer Software Company
20%
Manufacturing Company
8%
Healthcare Company
8%
Government
7%
Computer Software Company
14%
Financial Services Firm
10%
Manufacturing Company
8%
Government
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise13
Large Enterprise17
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What is your experience regarding pricing and costs for Proofpoint Email Protection?
In terms of pricing, it is okay compared to others. I would say it is normal. Additional costs do come in, but it enhances security.
What needs improvement with Proofpoint Email Protection?
I believe they still need to improve by consolidating some portals, as currently, you have to log in separately to a few of them.
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Proofpoint Enterprise Protection, Cofense PhishMe, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Proofpoint Email Protection and other solutions. Updated: September 2025.
868,787 professionals have used our research since 2012.