Try our new research platform with insights from 80,000+ expert users

Cisco Secure Email Threat Defense vs Proofpoint Email Protection comparison

Sponsored
 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Proofpoint Email Protection
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
51
Ranking in other categories
Security Awareness Training (2nd), Digital Risk Protection (3rd), Office 365 Protection (3rd), Secure Email Gateway (SEG) (2nd)
 

Mindshare comparison

As of May 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.9%, down from 18.3% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, down from 1.2% compared to the previous year. The mindshare of Proofpoint Email Protection is 8.1%, down from 11.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
AhmedRamadan - PeerSpot reviewer
Optimize email security with effective sandboxing and auto Pull for quarantine
Proofpoint is used as an email security gateway for big enterprises, primarily for their on-premises servers. Many customers also use it alongside Office 365 Proofpoint offers a complete solution for email security with features like DLP, email archiving, and encryption. The most valuable…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Our customers are satisfied with Defender for 365 because Microsoft products are easy to use and customize to meet the client's needs. Everything is in one place, so we can adjust policies as needed for phishing, DLP, ATP, or any other security features that our clients want to apply."
"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"It also gives the vulnerability status according to the versions you have selected. Let's say you have Google Chrome. It mentions the versions it has, and it updates. Within two hours of an update, it is reflected in the dashboard. That's really nice to have."
"Defender enables us to secure all 365-related activity from a single place. It gives us visibility into everything happening in Outlook, protecting us against phishing and other email-based threats. Defender helps us detect any suspicious behaviors."
"The most valuable feature of Microsoft Defender for Office 365 is its spam filter."
"The initial setup was easy."
"The product's scalability is good."
"The most valuable aspect of Microsoft Defender for Office 365 is its ability to protect us from malware."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"The product offers protection, email security, anti-spam, and antivirus."
"The solution is stable."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"Secure Email Threat Defense's scalability is good."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The solution scales quite well."
"The archive feature is valuable."
"The solution scales well."
"The solution has very strong detection for most of the phishing and malicious emails received from the outside."
"The anti-spam features are excellent on the email firewalls."
"The most valuable feature of Proofpoint Email Protection is the blocking capabilities, it blocks a lot of potential threats."
"The solution offers very good flexibility. You can blacklist or whitelist with ease."
"They have customized security rules, mature rules, anti-virus protection, as well as email authentication similar to SPF, DKIM, and DMARC."
 

Cons

"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"Microsoft sometimes has downtime, and we'll get several incidents coming in back to back. We have a huge backlog of notifications, many of which may be false positives. However, there might be serious alerts, so we can't risk dismissing all of them at once."
"In the areas of improvement for Microsoft Defender for Office 365, the console is the biggest challenge for me."
"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help."
"There's room for improvement regarding the time frame for retrieving emails."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"The phishing and spam filters could use some improvement."
"We encounter issues while searching for missing emails."
"The physical appliance has been discontinued, although the platform still exists."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"This solution could be improved by integration with Sandbox."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The email DLP portion could be a bit easier."
"In terms of improvement, the price could be better. Additionally, more security could be implemented."
"It has too many screens. It is kind of a conglomeration of products. In other words, they built product A, product B, and product C, and they are yet to integrate them into a single administrative console. I would certainly like to see a more seamless administrative interface. I would also like to see them include more bang for the buck, by including features like email fraud protection, rather than making their product so piecemeal, where you are buying little pieces. I agree with the idea of having multiple tiers or layers, but maybe as small, medium, and large, as opposed to an a la carte menu."
"Proofpoint Email Protection is an expensive solution."
"The scalability can be improved, and the solution can be optimized."
"The support team was a bit slow."
"We find the cost to be prohibitive."
"The stability and UI are the two areas of the solution with certain shortcomings that need improvement."
 

Pricing and Cost Advice

"The license is expensive because the cost is based on the number of users."
"It's a user-base subscription."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The product is very expensive."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"The solution charges per user per month to use it. There are not any additional fees in addition to the standard living fees."
"It is expensive."
"Clients pay for an annual subscription of Proofpoint Email Protection. Every client always finds it expensive."
"The licensing model for Proofpoint Email Protection is simple. It's based on the number of users. Price-wise, Proofpoint Email Protection is a five out of ten because it's a pretty expensive solution."
"Proofpoint Email Protection is a reasonably priced product, which means that it is neither too low nor too high in terms of price."
"I rate the product price a seven on a scale of one to ten, where one is low price and ten is high price."
"The licensing cost of Proofpoint Email Protection is a lot higher than other solutions, such as Barracuda."
"I rate the price of Proofpoint Email Protection a four out of five."
report
Use our free recommendation engine to learn which Email Security solutions are best for your needs.
851,604 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
34%
Financial Services Firm
6%
Government
5%
Healthcare Company
5%
Educational Organization
26%
Computer Software Company
12%
Financial Services Firm
8%
Manufacturing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What is your experience regarding pricing and costs for Proofpoint Email Protection?
In terms of pricing, it is okay compared to others. I would say it is normal. Additional costs do come in, but it enh...
What needs improvement with Proofpoint Email Protection?
In terms of improvement, the price could be better. Additionally, more security could be implemented.
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Proofpoint Enterprise Protection, Cofense PhishMe, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Proofpoint Email Protection and other solutions. Updated: April 2025.
851,604 professionals have used our research since 2012.