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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
7th
Average Rating
8.2
Reviews Sentiment
6.6
Number of Reviews
42
Ranking in other categories
Anti-Malware Tools (12th)
 

Mindshare comparison

As of January 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 4.4%, down from 7.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Exchange Online Protection (EOP)4.4%
Cisco Secure Email Threat Defense1.1%
Other94.5%
Email Security
 

Featured Reviews

reviewer2541525 - PeerSpot reviewer
Principal Cyber Prevent and Defense Engineer at a comms service provider with 1,001-5,000 employees
Clawback feature performs well but analytics and integration capabilities need improvement
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty in sending logs to our SIEM. Cisco Secure Email Threat Defense's flexibility could be enhanced while it mostly integrates with cloud solutions, but not on-premise. The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious. Regarding room for improvement, the significant number of false positives should be addressed. The solution does not adapt to behavioral analytics and does not make changes when it sees a pattern.
NancyHartman - PeerSpot reviewer
Business Process Manager/ Educational Technologist at a educational organization with 1,001-5,000 employees
Layered email security has protected sensitive research and still flags phishing in real time
The valuable features of Microsoft Exchange Online Protection (EOP) include providing an additional layer of protection, as it builds on the basic Exchange level of security that allows us to get our work done. Another feature I appreciate is the ability to question things, as our Exchange server allows us to identify in real-time if an email is a phishing email or spam email. It really helps us identify risks, especially through our external exchanges via email or through our cloud-based platforms. Our Exchange system blocks any embedded AI from all our applications and products, so we cannot use embedded AI in our daily work from our official laptops because we have secure information. The system is quite locked down.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It's very easy to deploy and configure."
"It has an efficient email filtering feature."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"This solution is easy to use."
"The solution is stable."
"Cisco Secure Email Threat Defense's best features include user management of graymail, enhancing security awareness by allowing users to manage cold calls, sales-based items, and ensuring email compliance."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"We use the solution in all our environments. We use it for remedy tickets and give them updates. It was our main communication point."
"The security features provided by Microsoft are robust."
"The most valuable feature of Microsoft Exchange Online Protection is the accidental release of information protection capabilities. Additionally, the solution is easy to use."
"Microsoft Exchange Online Protection (EOP) is used essentially for email filtering, acting as an anti-spam and security product for email."
"The threat management feature includes policies and alerts that are valuable."
"The email policy configuration options in Microsoft EOP are satisfactory."
"It is scalable."
"The solution's stability is very, very good. I didn't face any problems in the last year."
 

Cons

"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The solution is a bit expensive."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The physical appliance has been discontinued, although the platform still exists."
"The pricing could always be better."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"The tool is not 100% stable."
"The product's end-of-life cycle could be extended."
"It wasn't easy or intuitive enough for me to start using it. So, the reason was that the solution changed."
"Microsoft 365 Defender and EOP policies are stable with the proper license. However, with the basic policy, it's hard to say it's stable due to configuration limitations."
"I would like to get reports about vulnerable connections from our clients with information about domains, public IPs, etc. That would be highly useful."
"Having orchestration features added to Microsoft Exchange Online Protection, particularly automation and remediation, would be quite useful."
"The tool's classification for bulk email is cumbersome."
"Some of the searchability when looking for specifics in Exchange logs is tedious."
 

Pricing and Cost Advice

"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution should reduce the cost."
"The tool's pricing is excellent."
"The pricing of the solution is reasonable."
"The product is bundled with Microsoft 365."
"The solution falls on the higher or more expensive side of the spectrum."
"Microsoft Exchange Online Protection's pricing is a little bit more because its price has recently increased."
"Apart from the license fee for the solution, there are no additional costs."
"The pricing for the solution depends on what you are trying to achieve with the use of the product, but I know that it is not a cheaply priced product. Yearly payments have to be made towards the licensing fees of the solution."
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Marketing Services Firm
8%
Manufacturing Company
8%
Healthcare Company
7%
Computer Software Company
11%
Financial Services Firm
10%
Manufacturing Company
8%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise7
Large Enterprise11
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
The user interface of Microsoft Exchange Online Protection (EOP) has room for improvement, as at times it doesn't make sense where to go to access certain features.
What is your primary use case for Microsoft Exchange Online Protection?
My use case for Microsoft Exchange Online Protection (EOP) is basically to protect ourselves from phishing emails and to improve our email security.
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: December 2025.
881,082 professionals have used our research since 2012.