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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.9
Number of Reviews
15
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
6th
Average Rating
8.2
Reviews Sentiment
6.8
Number of Reviews
40
Ranking in other categories
Anti-Malware Tools (9th)
 

Mindshare comparison

As of August 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 6.0%, down from 8.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Amber Worth - PeerSpot reviewer
Retrieves data from quarantines and easy to read logs with robust security features
Some of the searchability when looking for specifics in Exchange logs is tedious. Although eventually the information is located, it can be difficult if detailed information is lacking. Improving the search process by allowing searches with different types of parameters and facilitating searches within emails would be advantageous. Simplifying interfaces would also be appreciated.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Secure Email Threat Defense's scalability is good."
"It has an efficient email filtering feature."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"This solution is easy to use."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"What I like most about Microsoft Exchange Online Protection is its integration with Windows, so we have one central view for all alerts and incidents."
"We use the solution to receive emails. We do not use the calendar function as our clients are slow adaptors to the latest features."
"The most valuable feature of Microsoft Exchange Online Protection is the accidental release of information protection capabilities. Additionally, the solution is easy to use."
"The initial setup of Microsoft Exchange Online Protection was easy."
"The initial setup was easy. The configuration process is very straightforward."
"It is scalable."
"It is easy to configure, easy to use, easy to add exclusions, easy to track, and easy to add anything else if you want."
"The most valuable feature is the ease of administration. Other solutions require complex administration, but Microsoft Exchange Online Protection is easier."
 

Cons

"The solution is a bit expensive."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The physical appliance has been discontinued, although the platform still exists."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"We encounter issues while searching for missing emails."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The product could be more stable. Microsoft products could be more stable because sometimes, even though they are updating some things, we cannot find those updates."
"Performance and speed should continue to be improved."
"It wasn't easy or intuitive enough for me to start using it. So, the reason was that the solution changed."
"The biggest issue that I experience is that Microsoft keeps moving things around, and it's very inconsistent as to where you find the information when you're trying to work on different pieces."
"When you're using a Microsoft product solution, you can scale it, but if you're not, there are limitations."
"The reporting needs a little bit of improvement."
"Microsoft has some training portals, but more could be developed."
"If a company wants to put in line back-to-back anti-spam solutions, they need to work on that part because Microsoft recommends either you use EOP as a front line or you don't use it."
 

Pricing and Cost Advice

"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution’s pricing is manageable."
"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"Regarding the price, it's comparable to other service providers. We've also looked at Check Point's offerings, and the pricing doesn't seem to be an issue."
"The pricing for the solution depends on what you are trying to achieve with the use of the product, but I know that it is not a cheaply priced product. Yearly payments have to be made towards the licensing fees of the solution."
"The tool's pricing is excellent."
"The price could be lower."
"The product is expensive."
"On a scale of one to ten, where one is cheap, and ten is very expensive, I rate the pricing a six. For licensing, we can make monthly or yearly payments. Right now, we pay 5 USD per month to secure a person's license."
"Microsoft Exchange Online Protection is a good solution at an affordable price. It is a good investment."
"Apart from the license fee for the solution, there are no additional costs."
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Top Industries

By visitors reading reviews
Computer Software Company
23%
Healthcare Company
8%
Government
6%
Manufacturing Company
6%
Computer Software Company
14%
Financial Services Firm
9%
Government
8%
Manufacturing Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
The pricing for Cisco Secure Email Threat Defense is relatively high. For an organization that already has the legacy system, it makes sense to continue hosting it. However, new organizations might...
What needs improvement with Secure Email Threat Defense?
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilitie...
What is your primary use case for Secure Email Threat Defense?
The main use case for Cisco Secure Email Threat Defense is as a gateway for email traffic into and out of the organization. It serves as the primary conduit for emails, providing content filtering,...
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
Reporting could be one of the areas for improvement, as they could put more reporting into Microsoft Exchange Online Protection (EOP) natively rather than requiring additional licensing or connecti...
What is your primary use case for Microsoft Exchange Online Protection?
The company does work with this technology, but not me personally. I manage some other products currently, mainly in the modern workplace space, such as Azure Virtual Desktop and Microsoft 365. I d...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: July 2025.
865,295 professionals have used our research since 2012.