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Palo Alto Networks WildFire vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Jun 3, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Palo Alto Networks WildFire
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
72
Ranking in other categories
No ranking in other categories
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
23rd
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of June 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Palo Alto Networks WildFire is 7.3%, down from 11.3% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.0%, up from 1.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Palo Alto Networks WildFire7.3%
Trellix Advanced Threat Defense2.0%
Other90.7%
Advanced Threat Protection (ATP)
 

Featured Reviews

RK
Engineer at Taalumgroup
Achieve effective threat prevention and seamless integration with powerful technical support
Integration with third-party products is possible. For example, connecting a mail gateway with Palo Alto Networks WildFire allows them to handle prevention. Palo Alto Networks WildFire is a cloud-based sandboxing solution. The firewall is connected to WildFire, and XDR performs sandboxing from the cloud. WildFire conducts malware scanning and emulation, then informs the firewall to block threats based on the response. It also generates reports regarding malware and other issues. The sandboxing process involves sending sample files to the cloud for scanning, checking file authenticity, certificates, and detecting malicious code. WildFire performs multiple checks and informs the XDR agent about file status. This automatic process occurs within minutes or seconds. For unknown or suspicious files, immediate blocking occurs while samples are sent to WildFire for identification. I rate Palo Alto Networks WildFire a 9 out of 10.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The cloud-based services are a nice feature."
"I value the massive usage of artificial intelligence and machine learning technologies."
"The most valuable feature is the cloud-based protection against zero-day malware attacks."
"It is a stable solution...It is a scalable solution."
"WildFire has been instrumental in blocking a number of new threats, before common desktop anti-virus tools were able to detect them."
"For example, if a security Intel threat talks about an IOC. We can then go to our MSP and say, "Is there a signature for this particular type of malware that just came out?" And if they'll say yes, then we'll say, "Okay. Does it apply to these firewalls? And have we seen any hits on it?" There's absolutely value in it."
"Palo Alto Networks WildFire is a very comprehensive device."
"Palo Alto's firewall is the best firewall right now."
"If a system admin can put in the patience to read and constantly update the ePO system in terms of rules, enforcing them at regular intervals, you can safely go to sleep every night."
"It was easy to set up initially."
"The features I find most valuable are: the management, the ability for automatic remediation of threats and it can successfully detect a threat, and to act upon it."
"I recommend this solution because of its ease of use."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"It is stable and reliable."
"Provides good exfiltration, and is an all-in-one product."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
 

Cons

"The threat intelligence that we receiving in the reporting was not as expected. We were expecting more. Additionally, we should be able to whitelist a specific file based on a variety of attributes."
"Palo Alto Networks WildFire is quite expensive, and this is what puts people off."
"The free version does not have real-time updates. It is slow."
"The system uptime data is unavailable"
"Improving detection on non-Windows formats would be beneficial as there are many samples, such as Linux or ransomware for macOS."
"Palo Alto doesn't do much to support the on-premise version. It wants too much self-support for the on-premise version of WildFire."
"​They provide a medium level of technical support."
"The support is quite difficult to access promptly. I rate it as seven out of ten."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"We'd like them to be better at dealing with script threats."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"This product does the job, but it is not flexible enough to do new environments yet."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
 

Pricing and Cost Advice

"It's pretty expensive but with respect to value for money, it's okay."
"We pay between $3,000 and $4,000 CAD ($2,200 - $3,000 USD) per year to maintain this solution."
"The pricing and licensing option should be categorized for various countries such as for Bangladesh."
"The solution is a bit expensive."
"I rate the pricing an eight out of ten since it can be pretty expensive."
"The price is fair and comparable to other solutions."
"The physical appliance is around €3,000 or €4,000, and then, you have the licensing for a year for around €3,000."
"The pricing is affordable and fixed."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
report
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Comparison Review

it_user206346 - PeerSpot reviewer
Security Consultant at Webernetz.net - Network Security Consulting
Mar 11, 2015
Cisco ASA vs. Palo Alto Networks
Cisco ASA vs. Palo Alto: Management Goodies You often have comparisons of both firewalls concerning security components. Of course, a firewall must block attacks, scan for viruses, build VPNs, etc. However, in this post I am discussing the advantages and disadvantages from both vendors concerning…
 

Top Industries

By visitors reading reviews
Manufacturing Company
11%
Computer Software Company
9%
Financial Services Firm
8%
Comms Service Provider
8%
Construction Company
17%
Financial Services Firm
12%
Comms Service Provider
10%
Outsourcing Company
10%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business38
Midsize Enterprise15
Large Enterprise29
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How does Cisco Firepower NGFW Firewall compare with Palo Alto Networks Wildfire?
The Cisco Firepower NGFW Firewall is a very powerful and very complex piece of anti-viral software. When one considers that fact, it is all the more impressive that the setup is a fairly straightf...
Which is better - Wildfire or FortiGate?
FortiGate has a lot going for it and I consider it to be the best, most user-friendly firewall out there. What I like the most about it is that it has an attractive web dashboard with very easy nav...
How does Cisco ASA Firewall compare with Palo Alto's WildFire?
When looking to change our ASA Firewall, we looked into Palo Alto’s WildFire. It works especially in preventing advanced malware and zero-day exploits with real-time intelligence. The sandbox featu...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

No data available
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Novamedia, Nexon Asia Pacific, Lenovo, Samsonite, IOOF, Sinogrid, SanDisk Corporation
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Palo Alto Networks WildFire vs. Trellix Advanced Threat Defense and other solutions. Updated: June 2026.
902,270 professionals have used our research since 2012.