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Palo Alto Networks WildFire vs Trellix Advanced Threat Defense comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Jun 3, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Palo Alto Networks WildFire
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
72
Ranking in other categories
No ranking in other categories
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
21st
Average Rating
7.8
Reviews Sentiment
5.6
Number of Reviews
9
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of November 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Palo Alto Networks WildFire is 6.6%, down from 9.4% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 2.1%, up from 1.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Palo Alto Networks WildFire6.6%
Trellix Advanced Threat Defense2.1%
Other91.3%
Advanced Threat Protection (ATP)
 

Featured Reviews

reviewer2695164 - PeerSpot reviewer
IT Security Specialist at a tech services company with 11-50 employees
Advanced threat detection has protected critical document workflows and checks suspicious files
I would say the setup and putting together the hierarchy within the devices was not straightforward. There were many reboots and reconfigurations while the optimal setup was established. However, we were happy with the device. The setup process could be easier to establish the cluster. It should be easier to establish the Palo Alto Networks WildFire cluster between the devices. We had some difficulty with it, but it was not catastrophic. The operation and usability itself is what I was happy with.
PP
RSSI at SDIS49
Ensuring long-term reliability while seeking internal email management enhancements
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it's a cloud product, so we don't really know the version as it's always updated. We have not had any problem, but it's difficult to report on what's going on because some days they can wash out perhaps 100 mails, and then it's difficult to say how many attacks you have reached. The right email has been washed out and then nobody has complained. We do not use the Threat Visualization feature; as we are in MX, the mail is washed out before it is in the mail inbox of the user, thus avoiding any problem requiring a reservation. In fact, there is no integration with existing security frameworks. The only problem we can have is that as we have no API interface, there is no inspection of internal mail. I rate Trellix Advanced Threat Defense a nine out of ten.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable feature is the improved security that it offers."
"The analysis is very fast."
"The cloud-based services are a nice feature."
"Palo Alto Networks WildFire is a good solution and it has been able to mitigate a lot of threats and attacks."
"They have many different options with Palo Alto WildFire and the set-up is quick. If you have all the details in hand, it does not take more than 15 minutes to deploy a firewall."
"The automated scanning capabilities integrated with Palo Alto's XDR are crucial for detecting and responding to potential environmental threats."
"After implementing the Palo Alto firewalls, they have achieved more than what is expected, and we are able to control the number of applications; who gets to have access, and what is flowing inside the network."
"Technical support is excellent and it is a promising option."
"The fact that in 10 years, we have had no problem is the most valuable feature for us; it's really a washing machine, but the only problem we face is that it's difficult to report on this product."
"The most valuable features are the administration console and its detection and response module."
"It is very scalable."
"I recommend this solution because of its ease of use."
"I see ROI, as it stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"This solution is very easy to use and requires little to no training."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"Provides good exfiltration, and is an all-in-one product."
 

Cons

"In the future, Palo Alto could reduce the time it takes to process the file."
"The initial setup was a little bit complex, mainly due to the GUI console and management challenges."
"​They provide a medium level of technical support."
"The cost of this solution could still be improved, in particular, giving product discounts for charitable causes."
"The product's false positive logs could be more user-friendly to understand. They could provide examples of precious cases to learn."
"The system performance degrades after the solution has been deployed for some time. The data that it gives us becomes a little bit slow. When you try to get some data for troubleshooting, it seems like it's working hard to extract that data."
"The free version does not have real-time updates. It is slow."
"The size of Palo Alto's cloud is big but it could be easier to use from a product management perspective."
"It was not complex, but there are things to look out for, because it's an intense product. It scans intensely and there are major obstacles to overcome if it scans while users are using a network, then it is not a good thing."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"The only problem we can have is that as we have no API interface, there is no inspection of internal mail."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"This product does the job, but it is not flexible enough to do new environments yet."
"Some of our customers have mentioned the lack of a tool that would allow for remote capabilities without being attached to the internet."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"Make the ATD appliance a part of the whole product offering and take the whole thing onto the cloud."
 

Pricing and Cost Advice

"It's pretty expensive but with respect to value for money, it's okay."
"Palo Alto Networks solutions are typically on the higher end of pricing, but considering the value and integration with our existing infrastructure, it is worth the investment."
"The physical appliance is around €3,000 or €4,000, and then, you have the licensing for a year for around €3,000."
"The pricing is highly expensive."
"It is a reasonable price compared to other solutions on the market."
"The price is expensive but is reasonable considering overall functionality."
"This solution is very pricey and it depends on the package that you implement."
"Palo Alto Networks WildFire is quite expensive, and this is what puts people off."
"Our licensing fees for this solution are approximately one million dollars per year."
"The product is expensive, but it is better than the rest of them in the industry."
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Comparison Review

it_user206346 - PeerSpot reviewer
Security Consultant at Webernetz.net - Network Security Consulting
Mar 11, 2015
Cisco ASA vs. Palo Alto Networks
Cisco ASA vs. Palo Alto: Management Goodies You often have comparisons of both firewalls concerning security components. Of course, a firewall must block attacks, scan for viruses, build VPNs, etc. However, in this post I am discussing the advantages and disadvantages from both vendors concerning…
 

Top Industries

By visitors reading reviews
Manufacturing Company
12%
Outsourcing Company
9%
Comms Service Provider
9%
Financial Services Firm
7%
Construction Company
15%
Outsourcing Company
15%
Financial Services Firm
13%
Manufacturing Company
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business38
Midsize Enterprise15
Large Enterprise30
By reviewers
Company SizeCount
Small Business3
Midsize Enterprise4
Large Enterprise5
 

Questions from the Community

How does Cisco Firepower NGFW Firewall compare with Palo Alto Networks Wildfire?
The Cisco Firepower NGFW Firewall is a very powerful and very complex piece of anti-viral software. When one considers that fact, it is all the more impressive that the setup is a fairly straightf...
Which is better - Wildfire or FortiGate?
FortiGate has a lot going for it and I consider it to be the best, most user-friendly firewall out there. What I like the most about it is that it has an attractive web dashboard with very easy nav...
How does Cisco ASA Firewall compare with Palo Alto's WildFire?
When looking to change our ASA Firewall, we looked into Palo Alto’s WildFire. It works especially in preventing advanced malware and zero-day exploits with real-time intelligence. The sandbox featu...
What needs improvement with McAfee Advanced Threat Defense?
I would like to see an API interface for internal email and control of outgoing email to make it closer to 10. It's necessary; today we have an MX interface, and it would be interesting to have an ...
What is your primary use case for McAfee Advanced Threat Defense?
We are working with Palo Alto products, specifically firewalls. We are only using Palo Alto Firewalls and not Cortex. With FireEye and Trellix, we only work with ETP now because the NDR function wh...
What advice do you have for others considering McAfee Advanced Threat Defense?
Prisma is a commercial name of the firewall now, but we don't work with the cloud product. Only our company is using it and we do not recommend it to customers. For us, it's transparent because it'...
 

Also Known As

No data available
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Novamedia, Nexon Asia Pacific, Lenovo, Samsonite, IOOF, Sinogrid, SanDisk Corporation
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Palo Alto Networks WildFire vs. Trellix Advanced Threat Defense and other solutions. Updated: September 2026.
920,769 professionals have used our research since 2012.