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Cortex Cloud by Palo Alto Networks vs Microsoft Defender Vulnerability Management comparison

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Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
5.5
Qualys TotalCloud boosts efficiency, reduces manual effort, decreases risk, and offers significant cost savings with a notable ROI.
Sentiment score
3.7
Cortex Cloud by Palo Alto Networks boosts efficiency and ROI with XSOAR integrations, though ROI quantification can be challenging.
Sentiment score
4.4
Microsoft Defender's financial benefits are unclear, best within E5 suite, and difficult to assess against AWS for mixed solution users.
It has saved about 90% of our time.
Senior Consultant at a consultancy with 10,001+ employees
TotalCloud has generated overall savings of 30 to 40 percent across various departments.
Security Manager at a consultancy with 10,001+ employees
CallStream helps us integrate and automate tasks.
Senior Security Consultant at CyberNxt Solutions LLP
The solution provides a good ROI, especially for regular customers, offering discounts for three-year licenses.
Senior Consultant at a tech vendor with 10,001+ employees
I don't think the tool in itself is very capable of doing that, but we have XSOAR and other tool integrations done on the platform, so this can be accomplished.
Technical Solutions Architect at IBM
Organizations typically do not rely solely on Microsoft products to avoid putting all eggs in one basket, which presents a challenge for maximizing ROI.
Cloud Security Engineer at a computer software company with 51-200 employees
As a Microsoft partner, we receive significant discounts, making the solution affordable for us.
COO at Floating-Dot Technology LTD
 

Customer Service

Sentiment score
7.4
Qualys TotalCloud support is praised for efficiency and staff knowledge but criticized for delays and inconsistent quality.
Sentiment score
6.6
Cortex Cloud's customer service is praised for prompt, knowledgeable support and effective troubleshooting, earning high user ratings.
Sentiment score
6.1
Microsoft Defender Vulnerability Management receives mixed reviews, highlighting expertise gaps and communication delays but valued for friendly assistance.
They are helpful, respond to my queries, and can answer any question.
Developer at a consultancy with 10,001+ employees
Qualys's tech support is highly responsive, providing multiple ways to interact with them.
Service Manager, Security Operations at CDA IT SOLUTIONS
Qualys' customer service provides quality answers, but the response time is long, even though it is within the SLA.
Works at a consultancy with 10,001+ employees
If I make it a high priority, they have resolved one query within 20 minutes.
Assistant Security Architect at Cloudnomics
If local Indian support cannot resolve an issue, global tech support aligns promptly within the agreed SLA.
Senior Consultant at a tech vendor with 10,001+ employees
Fast response times and knowledgeable staff who understand the intricacies of the system.
Principle Cloud Architect at a tech services company with 11-50 employees
They are sometimes responsive, however, often issues cannot be reproduced on their end, making it challenging.
Security Specialist at Prudential Systems Japan
The support we receive from Microsoft is declining, and for example, after taking advanced support, we have not received satisfactory answers.
Microsoft Solutions Manager at Self-Employed
They are familiar with Microsoft products but are not direct Microsoft staff, which is an area needing improvement.
Cloud Security Engineer at a computer software company with 51-200 employees
 

Scalability Issues

Sentiment score
7.8
Qualys TotalCloud excels in scalability, efficiently supporting diverse environments and business sizes, though it may require skilled management.
Sentiment score
4.5
Palo Alto's Cortex Cloud is scalable and efficient, with easy onboarding, but can be costly for higher licenses.
Sentiment score
7.0
Microsoft Defender Vulnerability Management is lauded for scalability and integration across environments, though some users seek improved documentation.
We started our organization about nine months back. We started with about 30 users, and we now have more than 100 users.
CIO at a venture capital & private equity firm with 11-50 employees
Our organization currently uses it to manage over 1200 web applications.
Analyst, Information Security at Infosys
It is absolutely scalable, and I would rate its scalability as nine out of ten.
retired at a consultancy with 10,001+ employees
For stability, scalability, mean time to response, and potential incident investigation improvements, I would give it a nine or probably even a ten.
Business Development Team Lead at a tech vendor with 201-500 employees
Onboarding endpoints and assets on Cortex Cloud by Palo Alto Networks is very easy.
Assistant Security Architect at Cloudnomics
The platform is able to auto-shut certain resources that are not in use through the agentless scan feature.
Technical Solutions Architect at IBM
The integration is straightforward for those who understand it, though documentation needs improvement.
Cloud Security Engineer at a computer software company with 51-200 employees
It is scalable; I evaluated the product and decided to use Defender on over 700 of our company servers.
Security Specialist at Prudential Systems Japan
 

Stability Issues

Sentiment score
8.3
Qualys TotalCloud is highly stable with reliable support, 99.9% uptime, minimal bugs, and effective maintenance communication.
Sentiment score
7.8
Cortex Cloud by Palo Alto Networks is praised for its stability, reliability, and seamless security performance without latency or issues.
Sentiment score
6.7
Microsoft Defender Vulnerability Management is appreciated for stability and ease despite resource intensity and occasional compatibility issues.
Overall, the support provided has been excellent.
Analyst, Information Security at Infosys
It is a stable solution, which is why we chose it.
CIO at a venture capital & private equity firm with 11-50 employees
Continuous monitoring is crucial to ensure system stability and avoid vulnerabilities or threats.
Developer at a consultancy with 10,001+ employees
My impression of Cloud Runtime Security in stopping attacks in real-time is that I have never had an issue where it has let something through, causing an outage or concerns to the customer.
Business Development Team Lead at a tech vendor with 201-500 employees
However, now in Cortex Cloud, I have not seen any lag or buffer.
Assistant Security Architect at Cloudnomics
My evaluation of how stable and reliable Cortex Cloud by Palo Alto Networks is very positive.
Technical Solutions Architect at IBM
There are compatibility issues occasionally arising with false positives when other security tools are not whitelisted in Microsoft Defender.
information Security and IT Manager at Discover Dollar Technologies Pvt Ltd.
It is very resource-intensive, consuming a lot of memory and CPU.
Security Specialist at Prudential Systems Japan
If Microsoft experiences downtime, this solution goes down as it is a SaaS-based solution where we have no control.
Cloud Security Engineer at a computer software company with 51-200 employees
 

Room For Improvement

Users suggest enhancing Qualys TotalCloud with clearer reports, better integration, intuitive UI, AI risk assessments, and improved documentation.
Cortex Cloud's interface and costs challenge users, with needs for improved integration, efficiency, and identity management features.
Microsoft Defender Vulnerability Management needs simplified configuration, better integration, faster updates, and advanced features for improved security and efficiency.
Ideally, the scanner should automatically detect and scan all subdomains, even if not explicitly defined, ensuring comprehensive vulnerability assessment.
Analyst, Information Security at Infosys
Ideally, updates should be more immediate, enabling quicker implementation of solutions.
Project Lead at Persistent Systems
Our goal is to integrate all these functions into Qualys, creating a single dashboard for comprehensive security monitoring and management.
Senior Information Security Engineer at a consultancy with 10,001+ employees
Regarding the generative AI security tool, I know for sure it's Agentic.
Cybersecurity Analyst at a tech services company with 11-50 employees
The solution is quite premium in cost compared to alternatives such as Wiz.
Principle Cloud Architect at a tech services company with 11-50 employees
There is not a clear MSP model compared to other vendors such as CrowdStrike.
Business Development Manager For Palo Alto Networks at a tech services company with 1,001-5,000 employees
This scoring should be for specific industries as well. If I belong to the healthcare industry using Microsoft Defender Vulnerability Management, it should provide me with a risk score and show how I fare against the risk score of my industry.
DGM. Technical Security at a tech services company with 10,001+ employees
A vulnerability I patch within 15 minutes takes 24 additional hours for an update.
information Security and IT Manager at Discover Dollar Technologies Pvt Ltd.
The product is not stable; it often uses excessive memory and CPU, which makes it slow.
Security Specialist at Prudential Systems Japan
 

Setup Cost

Qualys TotalCloud's pricing is high yet justified by comprehensive features and flexibility, benefiting larger enterprises seeking robust security.
Microsoft Defender Vulnerability Management offers competitive pricing in industry, though costs can be complex, especially for non-partners.
Qualys TotalCloud's pricing is currently acceptable, it is becoming increasingly expensive.
Senior Manager at a financial services firm with 10,001+ employees
Pricing is managed by our finance team; however, Qualys TotalCloud offers cost-effective licensing flexibility.
IT Manager at a consultancy with 10,001+ employees
Qualys TotalCloud is expensive, but it offers a premier solution with no headaches.
Vice President at Inspira Enterprise
The solution is costly, with high-end capabilities suitable for enterprises.
Senior Consultant at a tech vendor with 10,001+ employees
Today, it is smart and easy to calculate the licenses.
Cloud Security Manager at T-Systems International GmbH
Overall, every organization wishes for cheaper options, but we look at the security side as well, so we are good for now.
Senior Cloud Security Consultant at MetLife
For non-partners, however, the cost could be seen as higher, between seven to ten.
COO at Floating-Dot Technology LTD
The pricing is reasonable, and it's included in the whole Microsoft E5 bundle, so it's all-inclusive.
Corporate Planner at MISC Berhad
 

Valuable Features

Qualys TotalCloud offers comprehensive vulnerability detection, cloud security management, and automation with insightful dashboards for efficient threat management.
Cortex Cloud enhances security management with AI-driven threat detection, automation, and seamless CI/CD integration, reducing response times significantly.
Microsoft Defender offers asset discovery, real-time intelligence, seamless integration, risk prioritization, continuous monitoring, and proactive remediation with AI capabilities.
This view of risk helps reduce the work we would have to do to combine multiple sources to prioritize risk.
Works at a consultancy with 10,001+ employees
It will help cybersecurity professionals monitor the cloud and find vulnerabilities.
Developer at a consultancy with 10,001+ employees
We are enjoying the new feature, FlexScan, which is valuable for Internet-facing VMs.
Senior Consultant at a consultancy with 10,001+ employees
AI/ML aids in anticipating remediation for misconfigurations and vulnerabilities, and automatic remediation can be easily configured.
Senior Consultant at a tech vendor with 10,001+ employees
Cortex Cloud by Palo Alto Networks has reduced the time spent on incident investigations, and if I had to estimate, I would say it has cut our investigation time in half.
Sr. Compliance Analyst at a computer software company with 51-200 employees
This simplifies the management of shared responsibility among different people and entities, allowing you to use one single tool instead of having dozens of different tools to orchestrate and integrate.
Business Development Manager For Palo Alto Networks at a tech services company with 1,001-5,000 employees
The main advantage of Microsoft Defender Vulnerability Management is that it can locate and prevent most threats even when the endpoints are not connected to the corporate network, as long as the internet is available.
DGM. Technical Security at a tech services company with 10,001+ employees
The feature for customizing to region-specific and domain-specific requirements in healthcare is particularly beneficial.
Cloud Security Engineer at a computer software company with 51-200 employees
The most valuable aspect is the kind of assessment results I get, and the recommendations provided in Microsoft products really help in taking care of the resources.
Senior Cloud Security Consultant at MetLife
 

Categories and Ranking

Qualys TotalCloud
Sponsored
Ranking in Vulnerability Management
11th
Average Rating
8.6
Reviews Sentiment
7.3
Number of Reviews
39
Ranking in other categories
Container Security (11th), Cloud Workload Protection Platforms (CWPP) (8th), Cloud Security Posture Management (CSPM) (8th), SaaS Security Posture Management (SSPM) (1st), Cloud-Native Application Protection Platforms (CNAPP) (6th)
Cortex Cloud by Palo Alto N...
Ranking in Vulnerability Management
29th
Average Rating
8.6
Reviews Sentiment
5.7
Number of Reviews
11
Ranking in other categories
Cloud Workload Protection Platforms (CWPP) (13th), Cloud Security Posture Management (CSPM) (16th), Cloud-Native Application Protection Platforms (CNAPP) (11th), Data Security Posture Management (DSPM) (11th), Software Supply Chain Security (6th), Cloud Infrastructure Entitlement Management (CIEM) (7th), Application Security Posture Management (ASPM) (7th), Cloud Detection and Response (CDR) (6th)
Microsoft Defender Vulnerab...
Ranking in Vulnerability Management
13th
Average Rating
8.2
Reviews Sentiment
6.4
Number of Reviews
18
Ranking in other categories
Advanced Threat Protection (ATP) (20th), Microsoft Security Suite (17th), Risk-Based Vulnerability Management (6th)
 

Mindshare comparison

As of June 2026, in the Vulnerability Management category, the mindshare of Qualys TotalCloud is 1.0%, up from 0.9% compared to the previous year. The mindshare of Cortex Cloud by Palo Alto Networks is 1.1%, up from 0.2% compared to the previous year. The mindshare of Microsoft Defender Vulnerability Management is 1.6%, down from 3.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Vulnerability Management Mindshare Distribution
ProductMindshare (%)
Qualys TotalCloud1.0%
Microsoft Defender Vulnerability Management1.6%
Cortex Cloud by Palo Alto Networks1.1%
Other96.3%
Vulnerability Management
 

Featured Reviews

RO
IT Security Expert at Alior Bank S.A.
Unified risk scoring has improved our cloud visibility and simplifies remediation priorities
Qualys TotalCloud provides unified vulnerability and threat assessment across both IAS and SaaS. This solution provides a single prioritized view of risk, which helps reduce the work I would have to do. We are no longer based on CVSS; we are based on Qualys risk scoring, which is based on CVSS plus internal findings made by Qualys, and then assigns its own score. The TruRisk insight feature has found a small number of assets with high vulnerability scores, though I am cautious since some information is classified. Qualys TotalCloud has positively impacted our bank's performance, and we have definitely seen benefits after implementing this solution.
SJ
Technical Solutions Architect at IBM
Cloud security has improved as AI-driven runtime protection detects threats and reduces incidents
In my opinion, Cortex Cloud by Palo Alto Networks could be improved or enhanced in various ways. I don't have an idea about that yet because for that you actually need to use two or three different other tools to make a basic comparison. If you ask me how good the tool is, I would fairly rate it quite high. The tool is very popular, and customers can already see that it is one of the cloud leaders in the security space. The platform had a very good feature which provides documentation links about how to use a specific feature on the UI. It takes you to the proper documentation page where it suggests what to do and tells you about the steps that need to be done for a resource deployment. My thoughts about improving the product which I believe could greatly aid vendors is that it used to be a very user-friendly tool, but now they have incorporated everything under one umbrella. It has XDR, XSOAR, and Cortex Cloud by Palo Alto Networks. Before, we used to have separate modules and separate environments for each of these capabilities or features. Right now, it is a little complex and users would take their own time to know the tool better. This is something that would have been way better, but I would say there would be different opinions on this. Talking about user-friendliness, it has decreased now.
reviewer2770602 - PeerSpot reviewer
Cloud Security Engineer at a computer software company with 51-200 employees
Has helped with regional threat monitoring but needs better documentation and real-time capabilities
The documentation from Microsoft needs significant improvement. The documents are disorganized, with one document linking to another, making the steps unclear and difficult to follow. Regarding updates, it is not truly real-time as it takes between eight to twelve hours for updates to occur. It would be beneficial if updates could happen more quickly, perhaps within 10 minutes to half an hour. Support for integration and documentation needs to be more straightforward. The pricing is expensive, even though it is part of the E5 package.
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Top Industries

By visitors reading reviews
Manufacturing Company
18%
Financial Services Firm
14%
Construction Company
7%
Comms Service Provider
7%
Manufacturing Company
17%
Construction Company
11%
Financial Services Firm
8%
Outsourcing Company
7%
Financial Services Firm
12%
Manufacturing Company
10%
Computer Software Company
7%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise3
Large Enterprise29
By reviewers
Company SizeCount
Small Business7
Midsize Enterprise1
Large Enterprise4
By reviewers
Company SizeCount
Small Business9
Midsize Enterprise2
Large Enterprise8
 

Questions from the Community

What needs improvement with Qualys TotalCloud?
Areas that need improvement in every solution include the remediation part. The remediation steps should be simple en...
What is your primary use case for Qualys TotalCloud?
Our use case involves the assets that we have under cloud, the assets exposed to the internet, and the internal appli...
What is your experience regarding pricing and costs for Cortex Cloud by Palo Alto Networks?
I am not fully aware of the pricing and licensing of Cortex Cloud by Palo Alto Networks. The pricing is also based on...
What needs improvement with Cortex Cloud by Palo Alto Networks?
In my opinion, Cortex Cloud by Palo Alto Networks could be improved or enhanced in various ways. I don't have an idea...
What is your primary use case for Cortex Cloud by Palo Alto Networks?
The usual use cases for Cortex Cloud by Palo Alto Networks that I have been working with mostly are as simple as dete...
What needs improvement with Microsoft Defender Vulnerability Management?
Configuration of Microsoft Defender Vulnerability Management is something that needs improvement. In future updates o...
What is your primary use case for Microsoft Defender Vulnerability Management?
I can control the applications using Microsoft Defender Vulnerability Management, which are its best features for me ...
 

Also Known As

Qualys TotalCloud with FlexScan
No data available
No data available
 

Overview

Find out what your peers are saying about Cortex Cloud by Palo Alto Networks vs. Microsoft Defender Vulnerability Management and other solutions. Updated: June 2026.
900,747 professionals have used our research since 2012.